Results 151 to 160 of about 228,053 (289)

Capillary Electrophoresis as a Useful Tool to Separate Isomeric Opioid-Neurotensin Hybrid Peptides. [PDF]

Molecules
Zdunek J, Kleczkowska P, Szeleszczuk Ł, Kamysz W, Sikora K, Grodner B.   +5 more
europepmc   +1 more source

Decoding temporal miRNA signatures of semen under in vitro exposure for forensic time since deposition estimation using machine learning‐driven modeling

Interdisciplinary Medicine, EarlyView.
This study develops a novel miRNA‐based framework for estimating the time since deposition of semen stains, combining small RNA sequencing with machine learning. Time‐dependent miRNA modules were identified using Mfuzz clustering and WGCNA, followed by a multi‐stage feature selection pipeline that reduced 261 candidate miRNAs to a minimal 7‐miRNA panel.
Meiming Cai, Qiong Lan, Tong Xie, Qinglin Liu, Ming Zhao, Xiaolian Wu, Xin Shi, Ruonan Shen, Yiman Wu, Chen Mao, Bin Cong, Bofeng Zhu   +11 more
wiley   +1 more source

Machine learning-based cfDNA fragmentation profiling using automated capillary electrophoresis for early detection of hepatocellular carcinoma. [PDF]

Commun Med (Lond)
Udomruk S, Sutthitthasakul S, Bunsermvicha N, Pinyopornpanish K, Pruksakorn D, Charoenkwan P, Yongpitakwattana P, Khounkaew K, Jaimalai T, Duangsan T, Orrapin S, Moonmuang S, Noisagul P, Pasena A, Suksakit P, Gamngoen R, Teeyakasem P, Charoentum C, Kongkarnka S, Lapisatepun W, Chaiyawat P.   +20 more
europepmc   +1 more source

A dendrimer enhanced CRISPR/Cas12a performance for the evaluation of acidogenic capacity in cariogenic bacteria

Interdisciplinary Medicine, EarlyView.
A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang, Yining Zhao, Murtaza Sayed, Feng Chen, Juan Zhang   +4 more
wiley   +1 more source

Screening method for detection of genetically modified soybean and maize events using multiplex PCR combined with capillary electrophoresis. [PDF]

GM Crops Food
Park S, Lee SG, Shin K.
europepmc   +1 more source

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez, Sefa Küçükler, Selim Çomaklı, Hasan Şimşek, Özge Kandemir, Fatih Mehmet Kandemir, Şaban Maraşlı   +6 more
wiley   +1 more source

Tuning Apparent Peak Efficiency in Capillary Electrophoresis Using Backscatter Interferometry Detection. [PDF]

Electrophoresis
De Silva M, Kariuki SM, Dunn RC.
europepmc   +1 more source

Novel Laboratory Approaches in Heavy Chain Disease With Discordant Immunoglobulin Quantitation: A Case Report and Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
In this study, we investigated a rare case of γ‐heavy chain disease (γ‐HCD) through an integrated laboratory approach. Routine protein analyses (serum protein electrophoresis, immunotyping, and serum/urine immunofixation) identified an IgG monoclonal component without detectable light chains.
Eleonora Longhi, Artan Çeka, Fabiola Olivieri, Marco Moretti, Jacopo Sabbatinelli   +4 more
wiley   +1 more source

Determination of AAV Capsid Protein Ratios by Sodium Dodecyl Sulfate Capillary Electrophoresis (CE-SDS)-UV Absorption Method. [PDF]

Electrophoresis
Li Y, Sun Y, Li X, Bi H, Pei D, Fu Z, Ding Y, Pan Y, Qin X, Liang C, Wang L.   +10 more
europepmc   +1 more source

UGT1A1 Fragment Analysis: Genotyping the (TA)n Variable Repeat Polymorphism for Clinical Applications

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a PCR‐based fragment analysis assay for UGT1A1 rs3064744 targeting TA5 (*36), TA6 (*1), TA7 (*28), and TA8 (*37). The assay was CLIA validated with data showing 100% concordance and a sensitivity of 0.5 ng/uL. The assay was then implemented in a patient cohort of n = 940 and the results compared with PharmacoScan.
Ryan N. Baugher, Kristen M. Pike, Teri M. Plona, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Stephen M. Hewitt   +6 more
wiley   +1 more source