Results 81 to 90 of about 5,483,316 (290)

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

open access: yesAdvanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin   +18 more
wiley   +1 more source

Plan of Canberra, the federal capital of the Commonwealth of Australia [cartographic material] /

open access: yes, 1920
Street map of Canberra, Australian Capital Territory, showing constructed roads, bus routes, bus numbers in red, existing and proposed railway, division boundaries and city district boundaries. Relief shown by spot heights.; Possibly a base map overlayed
Australia. Federal Capital Commission.
core  

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou   +14 more
wiley   +1 more source

Cultural Capital and Cultural Participation

open access: yes, 2016
U radu se navode i analiziraju teorijski pristupi i istraţivački radovi kojima se pokušavaju objasniti trendovi u participaciju u kulturi u današnjim društvima.
Šljivečka, Ivan
core   +1 more source

Australian Capital Territory feature map [cartographic material] /

open access: yes, 1961
[Rev. ed.]. Blueline skeleton map on a cadastral base of Australian Capital Territory.; "Revised to April 61."; Based on Federal Territory feature map originally compiled by the Dept. of Home Affairs Lands and Surveys Branch, ca.
Australia. National Capital Development Commission.
core  

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun   +9 more
wiley   +1 more source

Leveraging organisational cultural capital

open access: yesSA Journal of Industrial Psychology, 2007
Organisational culture discourse mandates a linear approach of diagnosis, measurement and gap analysis as standard practice in relation to most culture change initiatives. Therefore, a problem solving framework geared toward “fixing ?
R Scheel, F Crous
doaj   +1 more source

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation

open access: yesAdvanced Science, EarlyView.
Phenylboronic acid‐functionalized gold nanoparticles reversibly attach to cell‐surface glycans, enhancing photoporation‐mediated intracellular delivery. After irradiation, ATP competitively disrupts the boronic ester interactions and removes cell‐associated nanoparticles, markedly reducing residual gold.
Tao Lu   +15 more
wiley   +1 more source

UN ESTUDIO ETNOGRÁFICO DE LAS PRÁCTICAS DE RESISTENCIA HACIA LA CULTURA ESCOLAR EN TRES INSTITUCIONES EDUCATIVAS DE BÁSICA SECUNDARIA EN LA CIUDAD DE CALI

open access: yesEntramado, 2010
El artículo tiene como objetivo general describir desde un enfoque cualitativo los comportamientos y actitudes de resistencia a la cultura escolar de los estudiantes de tres instituciones educativas de básica secundaria, de estratos uno, dos y tres en la
Holbein Giraldo Paredes
doaj  

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song   +6 more
wiley   +1 more source

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