Results 61 to 70 of about 938 (119)
Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
Advanced Science, Volume 12, Issue 34, September 11, 2025.These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.Xikai Liu, Xinran Liu, Mei Xue, Yushuo Xiao, Yuchen Chen, Rong Qiu, Di Wu, Yihao Zhou, Jiao Wang, Yan Yuan, Linwei Yu, Tianyi Shi, Yangkai Li, Hua Su, Hong Chen, Yong Liu, Kun Huang, Ling Zheng +17 morewiley +1 more sourceRecent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid
Chemistry – A European Journal, Volume 31, Issue 34, June 17, 2025.This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...Concetta Avitabile, Maria Teresa Cerasa, Antonia D'Aniello, Michele Saviano, Maria Moccia +4 morewiley +1 more sourceToward Design Principles for Biomolecular Condensates for Metabolic Pathways
Advanced Biology, Volume 9, Issue 5, May 2025.Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard +3 morewiley +1 more sourceSignatures of Selection for Resistance/Tolerance to Perkinsus olseni in Grooved Carpet Shell Clam (Ruditapes decussatus) Using a Population Genomics Approach
Evolutionary Applications, Volume 18, Issue 5, May 2025.ABSTRACT
The grooved carpet shell clam (Ruditapes decussatus) is a bivalve of high commercial value distributed throughout the European coast. Its production has suffered a decline caused by different factors, especially by the parasite Perkinsus olsenii. Improving production of R.Inés M. Sambade, João Estêvão, Marina Pampín, Andreia Cruz, Eric Guévélou, Andrés Blanco, Francisco Câmara, Jessica Gómez‐Garrido, Fernando Cruz, Luca Bargelloni, Stefano Carboni, Tyler Alioto, Benjamin Costas, Sergio Fernández‐Boo, Paulino Martínez +14 morewiley +1 more sourceOpinion and report of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) relating to an analysis of the health risks associated with exposure to caterpillars with stinging hairs and the development of management recommendations
Food Risk Assess Europe, Volume 3, Issue 2, April 2025.Abstract
Several species of Lepidoptera with caterpillars bearing urticating hairs are increasing their range in metropolitan France from year to year, such as the pine processionary (Thaumetopoea pityocampa Denis et Schiffermüller 1775) whose presence was historically limited to the south of France, and which is gradually being observed in the north ...Nicolas Desneux, Andrea Battisti, Anne‐Sophie Brinquin, Rudy Caparros‐Megido, Gilbert Gault, Carole Kerdelhué, Stéphane Krebs, Myriam Mérad, Catherine Pecquet, Tina Rambonilaza, Thomas Le Bourgeois, Philippe Castagnone, Thierry Candresse, Nicolas Desneux, Sandrine Eveillard, Florence Fontaine, Pascal Gentit, Martin Godefroidd, Lucia Guerin, Bruno Hostachy, Hervé Jactel, Eleni Kazakou, Christophe Le May, Eric Lombaert, David Markowski, Charles Manceau, Arnaud Monty, Maria Navajas, Céline Robin, Aurélien Sallé, Frédéric Suffert, Stéphan Steyer, Pierre‐Yves Teycheney, Eric Verdin, François Verheggen, Gilles Meyer, Xavier Bailly, Catherine Belloc, Stéphane Bertagnoli, Alain Boissy, Séverine Boullier, Henri‐Jean Boulouis, Eric Cardinale, Aurélie Courcoul, Alice De Boyer Des Roches, Barbara Dufour, Veasna Duong, Emmanuelle Gilot‐Fromont, Etienne Giraud, Lionel Grisot, Claire Guinat, Nadia Haddad, Elsa Jourdain, Hervé Juin, Sophie Le Bouquin‐Le Neveu, Caroline Le Maréchal, Sophie Le Poder, Yves Millemann, Pierre Mormède, Carole Peroz, Claire Ponsart, Céline Richomme, Claude Saegerman, Jean‐François Valarcher, Isabelle Vallée, Agnès Waret‐Szkuta, Natacha Woronoff‐Rehn, Georges De Sousa, Olivier Adam, Alain Aymard, Jean‐Christophe Cahuzac, Pierre Greve, Philippe Hartemann, Claire Hellio, Dominique Pessel, Vincent Richard, Christophe Soumet, Laura Maxim, Louis‐Georges Soler, Bénédicte Apouey, Luc Baumstark, Céline Bonnet, Thierry Brunelle, France Caillavet, Alain Carpentier, Thomas Coutrot, Cécile Detang‐Dessendre, Serge Garcia, Julien Gauthey, Emmanuelle Lavaine, Christine Le Clainche, Marc Leandri, Youenn Loheac, Sélim Louafi, Eric Plottu, Elodie Rouviere, Maïder Saint‐Jean, Denis Salles, Léa Tardieu, Jean‐Christophe Vergnaud, Jens Abildtrup, Catherine Collignon, Karine Fiore, Emeline Hily, Sandra Sinno‐Tellier, Emmanuel Gachet +105 morewiley +1 more sourceOpinion and report of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the assessment of the impact of fox population dynamics on public health
Food Risk Assess Europe, Volume 3, Issue 2, April 2025.ABSTRACT
The Red Fox (Vulpes vulpes) can be hunted as a game species. It may also be listed as a “species likely to cause damage” (ESOD – the acronym in French), for public health reasons among others. Conversely, benefits linked to the presence of foxes are also put forward, such as the predation of rodents carrying zoonotic agents.Emmanuelle Gilot‐Fromont, Isabelle Villena, Elsa Bonnaud, Claude Fischer, Etienne Giraud, Annick Linden, François Meurens, Carine Paraud, Francis Raoul, Céline Richomme, Sandrine Ruette, Michel Trommetter, Isabelle Vallée, Gilles Meyer, Xavier Bailly, Catherine Belloc, Stéphane Bertagnoli, Alain Boissy, Séverine Boullier, Henri‐Jean Boulouis, Eric Cardinale, Aurélie Courcoul, Alice De Boyer Des Roches, Barbara Dufour, Veasna Duong, Lionel Grisot, Claire Guinat, Nadia Haddad, Elsa Jourdain, Hervé Juin, Sophie Le Bouquin‐Le Neveu, Caroline Le Maréchal, Sophie Le Poder, Yves Millemann, Pierre Mormède, Carole Peroz, Claire Ponsart, Claude Saegerman, Jean‐François Valarcher, Isabelle Vallée, Agnès Waret‐Szkuta, Natacha Woronoff‐Rehn, Laura Maxim, Louis‐Georges Soler, Bénédicte Apouey, Luc Baumstark, Céline Bonnet, Thierry Brunelle, France Caillavet, Alain Carpentier, Thomas Coutrot, Cécile Detang‐Dessendre, Serge Garcia, Julien Gauthey, Emmanuelle Lavaine, Christine Le Clainche, Marc Leandri, Youenn Loheac, Sélim Louafi, Eric Plottu, Elodie Rouviere, Maïder Saint‐Jean, Denis Salles, Léa Tardieu, Jean‐Christophe Vergnaud, Philippe Fravalo, Frédéric Auvray, Mickaël Boni, Frédéric Borges, Gilles Bornert, Frédéric Carlin, Catherine Chubilleau, Monika Coton, Georges Daube, Noémie Desriac, Florence Dubois‐Brissonnet, Michel Federighi, Michel Gautier, Michèle Gourmelon, Sandrine Guillou, Stéphane Guyot, Didier Hilaire, Nathalie Jourdan‐da Silva, Claire Le Henaff‐Le Marrec, Sandra Martin‐Latil, Jeanne‐Marie Membré, Eric Oswald, Nadia Oulahal, Pascal Piveteau, Sabine Schorr‐Galindo, Régine Talon, Isabelle Villena, Emmanuelle Robardet, Nathalie Arnich, Karine Fiore, Florence Etoré, Véronique Raimond, Catherine Collignon +97 morewiley +1 more sourceTranscriptomic Profiles and Functional Correlates of Cancer‐Related Fatigue: A Cross‐Sectional Study in Women Undergoing Cancer Treatment
European Journal of Cancer Care, Volume 2025, Issue 1, 2025.Background and Objectives: Cancer‐related fatigue is a multifactorial condition that affects most people undergoing chemotherapy. To elucidate potential biological underpinnings of fatigue, this study tested correlations between patient‐reported fatigue and (1) functional measures and (2) transcriptomics of whole blood.Amber S. Kleckner, Evelina Mocci, Carin L. Clingan, Shari M. Youngblood, Paula Y. Rosenblatt, Katherine H. R. Tkaczuk, Ian R. Kleckner, Susan G. Dorsey, Pranshu Sahgal +8 morewiley +1 more sourcePeptide Nucleic Acids: From Origami to Editing
ChemPlusChem, Volume 89, Issue 11, November 2024.Peptide nucleic acids (PNAs) combine the programmability of native nucleic acids with the robustness and ease of synthesis of a peptide backbone. These designer biomolecules have demonstrated tremendous utility across a broad range of applications, from the formation of bespoke biosupramolecular architectures to biosensing and gene regulation.Liam M. Carson, Emma E. Watsonwiley +1 more sourceCell dehydration enables massive production of engineered membrane vesicles with therapeutic functions
Journal of Extracellular Vesicles, Volume 13, Issue 7, July 2024.Abstract
Extracellular vesicles (EVs) have emerged as promising biomaterials for the treatment of different disease. However, only handful types of EVs with clinical transformation potential have been reported to date, and their preparation on a large scale under biosafety‐controlled conditions is limited. In this study, we characterize a novel type of Jie Liu, Tingting Shen, Yu Zhang, Xiaojian Wei, Yuting Bao, Rui Ai, Shaoju Gan, Dachi Wang, Xin Lai, Libo Zhao, Wei Zhou, Xiaohong Fang +11 morewiley +1 more source
