Results 11 to 20 of about 7,894 (243)

MicroRNA-181a Functions as an Oncogene in Gastric Cancer by Targeting Caprin-1

open access: yesFrontiers in Pharmacology, 2019
MicroRNA-181a (miRNA-181a) is a multifaceted miRNA implicated in various cellular processes, particularly in cell fate determination and cellular invasion.
Yanchun Chen, Fenghua Zhou
exaly   +4 more sources

Structural insights into the Caprin-2 HR1 domain in canonical Wnt signaling [PDF]

open access: yesJournal of Biological Chemistry
The canonical Wnt signaling pathway plays crucial roles in cell fate decisions as well as in pathogenesis of various diseases. Previously, we reported Caprin-2 as a new regulator of canonical Wnt signaling through a mechanism of facilitating LRP5/6 ...
Lin Li
exaly   +3 more sources

Fission yeast Caprin protein is required for efficient heterochromatin establishment. [PDF]

open access: yesPLoS Genet
Heterochromatin is a key feature of eukaryotic genomes that serves important regulatory and structural roles in regions such as centromeres. In fission yeast, maintenance of existing heterochromatic domains relies on positive feedback loops involving ...
Zhang H   +5 more
europepmc   +3 more sources

Defining the Caprin-1 Interactome in Unstressed and Stressed Conditions

open access: yesJournal of Proteome Research, 2021
Cytoplasmic stress granules (SGs) are dynamic non-membranous foci containing translationally arrested mRNA and RNA binding proteins that form in response to a variety of cellular stressors.
Lucas Vu, Asmita Ghosh, Hadjara Sidibé
exaly   +2 more sources

Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice [PDF]

open access: yesBiochimica Et Biophysica Acta - Molecular Basis of Disease, 2013
Osteosarcoma (OS) is the most common primary bone malignancy in children and adolescents. More than 30% of patients develop lung metastasis, which is the leading cause of mortality.
Josefine Bertz, Urs Ziegler
exaly   +2 more sources

Productivité des caprins dans les systèmes de production agricole du Delta du fleuve Sénégal [PDF]

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996
A travers l'analyse de la productivité, les auteurs présentent les principaux paramètres zootechniques de cheptel caprin du Delta du fleuve Sénégal, et les comparent aux références disponibles pour la même et quelques autres grandes zones agro ...
Jean-François Tourrand, Etienne Landais
doaj   +3 more sources

Caprin‑1 promotes HepG2 cell proliferation, invasion and migration and is associated with poor prognosis in patients with liver cancer

open access: yesOncology Letters, 2020
The present study aimed to investigate the role of caprin-1 in liver cancer and its association with the clinicopathological features and prognosis of liver cancer, as well as the underlying mechanism of caprin-1 function. Caprin-1 expression levels in a
Xin-Min Guo
exaly   +2 more sources

Expression and tumor-promoting effects of caprin-1 in human glioma

open access: yesGlioma, 2018
Background: Cytoplasmic activation/proliferation-associated protein-1 (caprin-1) is a newly discovered RNA-binding protein and is now recognized as one of the putative oncogenes.
Li Zhang   +9 more
doaj   +2 more sources

Crystal structure of a dimerization domain of human Caprin-2: similar overall dimeric fold but different molecular surface properties to that of human Caprin-1

open access: yesJournal of Biomolecular Structure and Dynamics, 2019
Human Caprin-1 and Caprin-2 are prototypic members of the caprin (cytoplasmic activation/proliferation-associated protein) protein family. Vertebrate caprin proteins contain two highly conserved homologous regions (HR1 and HR2) and C-terminal RGG motifs.
Xiaolan Huang, Xia Zhou, Zhihua Du
exaly   +2 more sources

Chemoimmunotherapy in Advanced, PD-1 Refractory Cutaneous Squamous Cell Carcinoma: Insights From Two Immunocompromised Patient Cases. [PDF]

open access: yesCase Rep Oncol Med
Cutaneous squamous cell carcinoma (cSCC) is one of the most prevalent malignancies worldwide, and a subset of patients, particularly immunocompromised individuals, will face heightened risks of metastasis and mortality. This report examines two cases of immunocompromised patients treated with a combination of platinum‐ and taxane‐based chemotherapy ...
Rahimi G, In GK.
europepmc   +2 more sources

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