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Development of a double-antigen sandwich ELISA for rapid and accurate detection of antibodies against Capripoxvirus [PDF]

open access: yesMicrobiology Spectrum
Lumpy skin disease, goatpox, and sheeppox have rapidly spread in many countries, leading to the emergence of new mutant strains that have caused substantial damage and posed significant threats to animal husbandry in endemic areas. Effective surveillance
, Hong Tian, Haixue Zheng
exaly   +4 more sources

Capripoxvirus Infections in Ruminants: A Review

open access: yesMicroorganisms, 2021
Lumpy skin disease, sheeppox, and goatpox are notifiable diseases of cattle, sheep, and goats, respectively, caused by viruses of the Capripoxvirus genus. They are responsible for both direct and indirect financial losses.
Jihane Hamdi   +2 more
exaly   +3 more sources

BelloStageā„¢-3000 Bioreactor Versus Conventional Cultivation of Recombinant Capripoxvirus Expressing Brucella Antigens in Vero Cells: A Step Towards the Development of a New Human Brucellosis Vaccine [PDF]

open access: yesCells
Brucellosis remains one of the most significant zoonotic diseases, posing a serious threat to both human health and livestock. This issue is particularly relevant for Kazakhstan, which is among the countries endemic for brucellosis with a high incidence ...
Zhanat Amanova   +10 more
doaj   +2 more sources

Exploring the evolutionary journey of the lumpy skin disease virus through the phylogenetic and phylo-geo network analysis [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
IntroductionLumpy Skin Disease Virus (LSDV), an emerging pathogen from the Capripoxvirus genus, continues to challenge global livestock health with its expanding host range and genetic adaptability.Materials and methodsIn this study, we report the first ...
Manjunatha Reddy Gundallahalli Bayyappa   +8 more
doaj   +2 more sources

Harnessing Attenuation-Related Mutations of Viral Genomes: Development of a Serological Assay to Differentiate between Capripoxvirus-Infected and -Vaccinated Animals

open access: yesViruses, 2023
Sheeppox, goatpox, and lumpy skin disease caused by the sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV), respectively, are diseases that affect millions of ruminants and many low-income households in endemic countries ...
Angelika Loitsch   +2 more
exaly   +3 more sources

Which Proteins? The Challenge of Identifying the Protective Antigens for Next-Generation Capripoxvirus Vaccines [PDF]

open access: yesVaccines
Sheeppox, goatpox, and lumpy skin disease continue to negatively impact the sheep, goat, and cattle industries in countries where these diseases are present and threaten to spread into new regions. Effective vaccines are available for disease control and
Mahder Teffera   +3 more
doaj   +2 more sources

Development and Optimization of Indirect ELISAs for the Detection of Anti-Capripoxvirus Antibodies in Cattle, Sheep, and Goat Sera

open access: yesMicroorganisms, 2022
Sheeppox (SPP), goatpox (GTP), and lumpy skin disease (LSD) are economically significant pox diseases of ruminants, caused by sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV), respectively.
Esayas Gelaye   +2 more
exaly   +3 more sources

Development and evaluation of an experimental inactivated vaccine against lumpy skin disease [PDF]

open access: yesVeterinary World
Background and Aim: Lumpy skin disease (LSD), caused by the LSD virus (LSDV), results in severe economic losses, reduced productivity, and restricted livestock trade. Although live attenuated vaccines are available, they pose risks such as viral shedding,
Adil Shahzad   +4 more
doaj   +2 more sources

In Silico Analysis of Honey Bee Peptides as Potential Inhibitors of Capripoxvirus DNA-Directed RNA Polymerase

open access: yesAnimals, 2023
The genus Capripoxvirus belongs to the Poxviridae family. The sheeppox, goatpox, and lumpy skin disease viruses are three species of this genus with 96% identity in their genomes.
Ghulam Mustafa   +2 more
exaly   +3 more sources

Different Neutralizing Antibody Responses of Heterologous Sera on Sheeppox and Lumpy Skin Disease Viruses [PDF]

open access: yesViruses
Sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV) are the three members of the genus Capripoxvirus within the Poxviridae family and are the etiologic agents of sheeppox (SPP), goatpox (GTP), and lumpy skin disease (LSD ...
Francisco J. Berguido   +6 more
doaj   +2 more sources

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