Different Neutralizing Antibody Responses of Heterologous Sera on Sheeppox and Lumpy Skin Disease Viruses [PDF]
VirusesSheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV) are the three members of the genus Capripoxvirus within the Poxviridae family and are the etiologic agents of sheeppox (SPP), goatpox (GTP), and lumpy skin disease (LSD ...
Richard T Kangethe +2 more
exaly +4 more sources
Risk expression using likelihood ratios and natural frequencies in Bayesian inference tasks—a preregistered randomized-controlled crossover trial [PDF]
BMC Medical EducationBackground To make reasonable future medical decisions, medical students need to be sufficiently educated to interpret diagnostic tests. Natural frequencies are considered the gold standard for understanding single diagnostic test results.
Philipp Schulz +2 more
doaj +4 more sources
Isolation of Lumpy Skin Disease Virus Isolated from SPPV Vaccinated Cattle [PDF]
Journal of Veterinary Medical Research, 2021 Massive outbreaks of suspected LSDV in cattle population were observed during 2017 and 2018 at Beni-Suef governorate. Samples from diseased cattle, previously SPPV vaccinated with SPPV, were inoculated in embryonated chicken eggs (ECE) using chorio-allantoic membrane (CAM) route.
Hanafy M Madbouly
exaly +2 more sources
Cross-Protection of an Inactivated and a Live-Attenuated Lumpy Skin Disease Virus Vaccine against Sheeppox Virus Infections in Sheep [PDF]
Vaccines, 2023 Sheeppox virus (SPPV) (genus Capripoxvirus, family Poxviridae) infections are a highly virulent and contagious disease of sheep with a high morbidity and mortality, especially in naïve populations and young animals.
Janika Wolff +2 more
doaj +3 more sources
Frontiers in Immunology, 2021 Sheeppox (SPP) is a highly contagious disease of small ruminants caused by sheeppox virus (SPPV) and predominantly occurs in Asia and Africa with significant economic losses. SPPV is genetically and immunologically closely related to goatpox virus (GTPV)
Richard T Kangethe +2 more
exaly +3 more sources
Humoral Response in Cattle Vaccinated with the Heterologous Sheeppox Virus Vaccine for Protection Against Lumpy Skin Disease: A Field Study [PDF]
VaccinesBackground/Objectives: Lumpy skin disease (LSD) is a notifiable disease due to a marked potency for rapid spread and a significant negative economic impact on agriculture worldwide. As such, vaccination is considered the most effective way to control the
Anna M. Lyapina +6 more
doaj +2 more sources
Establishment of a Challenge Model for Sheeppox Virus Infection
Microorganisms, 2020 Sheeppox virus (SPPV) together with goatpox virus and lumpy skin disease virus form the genus Capripoxvirus of the Poxviridae family. Due to their great economic importance and major impact on livelihood of small-scale farmers, OIE guidelines classify ...
Janika Wolff +2 more
exaly +3 more sources
Molecular Determinants of Species-Specific Interactions Between Protein Kinase R and Poxvirus K3 Orthologs [PDF]
VirusesProtein kinase R (PKR) is an antiviral protein that is involved in molecular “arms races” with viral antagonists. As a result, some PKR inhibitors, including the vaccinia virus (VACV) protein K3 and its orthologs from other poxviruses only inhibit PKRs ...
Chorong Park +6 more
doaj +2 more sources
Identification of a novel monoclonal antibody derived from the lumpy skin disease virus ORF123 that confers cross-binding and cross-neutralizing activity against Capripoxvirus members [PDF]
Veterinary ResearchCapripoxviruses cause diseases (e.g., lumpy skin disease, sheep pox, and goat pox) that significantly hinder the growth of livestock production in endemic areas.
Shanhui Ren +12 more
doaj +2 more sources
BelloStage™-3000 Bioreactor Versus Conventional Cultivation of Recombinant Capripoxvirus Expressing Brucella Antigens in Vero Cells: A Step Towards the Development of a New Human Brucellosis Vaccine [PDF]
CellsBrucellosis remains one of the most significant zoonotic diseases, posing a serious threat to both human health and livestock. This issue is particularly relevant for Kazakhstan, which is among the countries endemic for brucellosis with a high incidence ...
Zhanat Amanova +10 more
doaj +2 more sources