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A GTPV-Based Murine Model Recapitulating Key Features of Lumpy Skin Disease for Preclinical Vaccine Evaluation [PDF]

open access: yesAnimals
The global spread of lumpy skin disease (LSD), a devastating cattle disease caused by the lumpy skin disease virus (LSDV), is hampered by the lack of a practical small animal model for vaccine evaluation. Here, we established a mouse model by challenging
Sen Zhang, Aizhen Guo, Yingyu Chen
exaly   +5 more sources

Use of an Alignment-Free Method for the Geographical Discrimination of GTPVs Based on the GPCR Sequences [PDF]

open access: yesMicroorganisms, 2021
Goatpox virus (GTPV) belongs to the genus Capripoxvirus, together with sheeppox virus (SPPV) and lumpy skin disease virus (LSDV). GTPV primarily affects sheep, goats and some wild ruminants.
Jacqueline Kasiiti Lichoti   +2 more
exaly   +7 more sources

Goatpox virus Hrf-063 interacts with host eIF4A1 and is associated with altered expression of antiviral signaling-related factors [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
Goatpox virus (GTPV) is an important capripoxvirus that causes severe disease in goats, yet the functions of many GTPV-encoded proteins remain unclear. In this study, eukaryotic translation initiation factor 4A1 (eIF4A1) was identified as a host protein ...
Baoqin Long   +32 more
doaj   +2 more sources

Identification of a novel monoclonal antibody derived from the lumpy skin disease virus ORF123 that confers cross-binding and cross-neutralizing activity against Capripoxvirus members [PDF]

open access: yesVeterinary Research
Capripoxviruses cause diseases (e.g., lumpy skin disease, sheep pox, and goat pox) that significantly hinder the growth of livestock production in endemic areas.
Shanhui Ren   +12 more
doaj   +2 more sources

Experimental Infection and Genetic Characterization of Two Different Capripox Virus Isolates in Small Ruminants

open access: yesViruses, 2020
Capripox viruses, with their members “lumpy skin disease virus (LSDV)”, “goatpox virus (GTPV)” and “sheeppox virus (SPPV)”, are described as the most serious pox diseases of production animals.
Janika Wolff   +2 more
exaly   +3 more sources

A novel triplex real-time PCR assay for the differentiation of lumpy skin disease virus, goatpox virus, and sheeppox virus

open access: yesFrontiers in Veterinary Science, 2023
IntroductionThree members of Capripoxvirus (CaPV) genus, including lumpy skin disease virus (LSDV), goatpox virus (GTPV), and sheeppox virus (SPPV), are mentioned as notifiable forms by World Organization for Animal Health.
Wenlong Nan, Chunju Liu, Faxing Wu
exaly   +3 more sources

Exploring the function and pathogenicity of Goatpox virus N1L gene using recombinant vaccinia virus Tiantan strain [PDF]

open access: yesFrontiers in Veterinary Science
The N1L gene is a well-characterized virulence factor in the poxvirus family; however, its functional role in Goatpox virus (GTPV) remains poorly understood.
Jialiang Xin   +12 more
doaj   +2 more sources

Optimal immunization strategies for Saanen goats against goatpox [PDF]

open access: yesBMC Veterinary Research
Background Goatpox is a highly contagious disease caused by the Capripoxvirus, primarily affecting sheep and goats. Breeds like the Saanen are particularly vulnerable, especially in enzootic areas, and face risks not only from the disease itself but also
Hossein Esmaeili   +6 more
doaj   +2 more sources

Live attenuated goatpox vaccination in pregnant Murcia-Granada goats: dosage implications and outcomes [PDF]

open access: yesBMC Veterinary Research
Background Infectious diseases, particularly the Goatpox virus (GTPV) from the Poxviridae family, significantly impact livestock health and agricultural economies, especially in developing regions.
Hossein Esmaeili   +4 more
doaj   +2 more sources

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