Research Review on Inhibitors of Lumpy Skin Disease Virus: From Biological Characteristics, Drug Repurposing, to Computer-Aided Drug Design. [PDF]
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct‐acting poxvirus inhibitors and host‐directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and ...
Zhao L +6 more
europepmc +2 more sources
Phylogenetic Analysis, Morphological Characteristics, and Cellular Tropism of Vaccine-Like Recombinant Strains of Lumpy Skin Disease Virus in China. [PDF]
Lumpy skin disease virus (LSDV) causes lumpy skin disease (LSD), a highly contagious cattle disease that leads to substantial economic losses to the global cattle industry. Currently, it is imperative to further elucidate its biological characteristics and analyze the global epidemiological dynamics.
Gong Z +12 more
europepmc +2 more sources
A Genome-Wide Screening of Novel Immunogenic TrLSDV103 Protein of Lumpy Skin Disease Virus and Its Application for DIVA. [PDF]
Using the VirScan platform covering 4522 LSDV protein sequences, sera from 20 LSDV‐infected and 20 GTPV‐vaccinated cattle were used to screen phage libraries. Sequencing and bioinformatics analyses revealed peptides covering the TrLSDV103 protein. The candidate antigen was subsequently expressed, confirmed for its DIVA capability, and used to develop ...
Yuan X +5 more
europepmc +2 more sources
Epidemiological Study and Molecular Characterization of Lumpy Skin Disease in Cattle in Egypt. [PDF]
Lumpy skin disease virus (LSDV) constitutes one of the most significant poxvirus infections impacting livestock and has a high morbidity rate and a comparatively low mortality rate. This study was designed to elucidate the epidemiology and the molecular analysis of LSDV using conventional polymerase chain reaction (PCR) to amplify the extracellular ...
El-Nady HH +8 more
europepmc +2 more sources
Development of a Multi-Locus Real-Time PCR with a High-Resolution Melting Assay to Differentiate Wild-Type, Asian Recombinant, and Vaccine Strains of Lumpy Skin Disease Virus. [PDF]
Lumpy skin disease virus (LSDV) affects cattle and causes significant economic damage. The live vaccine derived from an attenuated strain is effective but is associated with mild disease and skin lesions in some vaccinated cattle.
Bhakha K +11 more
europepmc +3 more sources
Genetic Evolutionary Analysis of Lumpy Skin Disease Virus Strain Under Immune Pressure Exerted by Heterologous Goat Poxvirus Vaccines. [PDF]
Lumpy skin disease (LSD) is an important infectious disease that threatens the global cattle industry. Recently, LSD has occurred frequently in Asia. The attenuated goat poxvirus (GTPV) vaccine is widely used to prevent LSD in cattle in China; however, sporadic cases of LSD still occur in immunized cattle.
Chang W +9 more
europepmc +2 more sources
Development of a potential vaccine against Capripox virus implementing reverse vaccinology and pan-genomic immunoinformatics. [PDF]
CPXV is responsible for animal diseases affecting cattle (Lumpy Skin Disease), sheep (Sheeppox), and goats (Goatpox). During outbreaks, these diseases have huge socio-economic effects.
Md Mohaimenul Islam Tareq +9 more
doaj +2 more sources
Development of a cost-effective method for capripoxvirus genotyping using snapback primer and dsDNA intercalating dye [PDF]
Sheep pox virus (SPPV), goat pox virus (GTPV) and lumpy skin disease virus (LSDV) are very closely related viruses of the Capripoxvirus (CaPV) genus of the Poxviridae family.
Diallo, Adama +5 more
core +9 more sources
The genus Capripoxvirus belongs to the Poxviridae family. The sheeppox, goatpox, and lumpy skin disease viruses are three species of this genus with 96% identity in their genomes.
Ghulam Mustafa +6 more
doaj +1 more source
Contribution of the practice of resistance exercises and the type of delivery to the diastasis of the rectus abdominis muscles in primiparous women [PDF]
El cuerpo materno sufre cambios fisiológicos ybiomecánicos durante el embarazo, entre los cuales se destacael alejamiento de los músculos rectos abdominales (MRA).Los objetivos de este estudio transversal fueron: comparar ladistancia entre los MRA entre ...
Aquino, Cecília Ferreira de +14 more
core +2 more sources

