Results 11 to 20 of about 554 (134)

Molecular Chain Elongation Mechanism for n-Caproate Biosynthesis by Megasphaera Hexanoica. [PDF]

Adv Sci (Weinh)
The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Jeon BS, Kim EJ, Seo H, Kim H, Shin S, Schlaiß C, Angenent LT, Kim KJ, Sang BI.   +8 more
europepmc   +2 more sources

Impact of conductive magnetite nanoparticles and anode polarization on glucose fermentation

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Electrically conductive materials and electrochemical stimulation strategies are increasingly explored to steer microbial fermentation towards desired metabolic outputs. These approaches also hold remarkable potential to couple wastewater treatment (WWT) to the production of value‐added compounds, in turn enhancing environmental ...
Clara Marandola, Silvia Bolognesi, Matteo Tucci, Marco Resitano, Carolina Cruz Viggi, Sebastià Puig, Marianna Villano   +6 more
wiley   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source

A Scoping Review of Certified Nurse‐Midwife and Certified Midwife Care in the United States: Assessing Outcomes Across Six Patient Care Domains

The Milbank Quarterly, EarlyView.
Policy Points Certified nurse‐midwife (CNM)/certified midwife (CM) care is associated with outcomes that are comparable or improved compared to physician care across multiple domains of health care quality, especially safety and effectiveness. CNM/CM care is consistently associated with lower rates of intrapartum interventions and improved birth ...
EMMA VIRGINIA CLARK, ROBYN SCHAFER, RACHEL LANE WALDEN, JULIE BLUMENFELD, CARRIE E. NEERLAND, KATIE PAGE, MAVIS N. SCHORN, SANJANA CHIMATA, HEATHER M. BRADFORD   +8 more
wiley   +1 more source

Prenatal 17‐Alpha‐Hydroxyprogesterone Caproate Exposure in Twins and Childhood Outcomes: 14‐Year Follow‐Up of a Randomised Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Long‐term child outcomes after intra‐uterine exposure to 17‐alpha‐hydroxyprogesterone caproate (17‐OHPC) versus placebo. Design Follow‐up of the AMPHIA randomised controlled trial assessing neonatal outcomes after weekly 17‐OHPC injections compared to placebo in multiple pregnancies. Setting Multicentre. Population or Sample Children
Emilie V. J. van Limburg Stirum, Marjon A. de Boer, A. C. J. Ravelli, Rik van Eekelen, Aleid G. Leemhuis, Martijn J. J. Finken, Cornelieke S. H. Aarnoudse‐Moens, Anneloes L. van Baar, Noor E. Simons, Rebecca C. Painter, Arianne C. Lim, Ben W. Mol, Eva Pajkrt, Martijn A. Oudijk, Janneke van 't Hooft   +14 more
wiley   +1 more source

Forage Level and Methane Inhibitor Effects on In Vitro Fermentation Products Using Forage Rape or Ryegrass as Substrates

New Zealand Journal of Agricultural Research, Volume 69, Issue 2, April 2026.
Dietary approaches that decrease ruminal pH may be combined with anti‐methanogenic feed additives that prevent methane formation and consequently increase the dissolved hydrogen concentration. To evaluate the effect of pH and the effect of dissolved hydrogen concentration, two forages (forage rape and ryegrass) were incubated in vitro at two forage ...
Maria M. Della Rosa, Stefan Muetzel, Peter H. Janssen, David Pacheco, Arjan Jonker   +4 more
wiley   +1 more source

Exploring the Controllability of Microbial Metabolism on the Flavor of Chinese Baijiu

eFood, Volume 7, Issue 1, February 2026.
Regulation of flavor compounds by core functional microorganisms. ABSTRACT The flavor and quality of Baijiu are closely related to the environment and microbial metabolism. The microbial community structure is highly dynamic in time and space, making it trouble to control the flavor and quality of Baijiu. Therefore, this paper reviewed the role of core
Hang Ying, Xing Guo, Yifan Cheng, Qinglin Sheng, Yane Luo, Yahong Yuan, Tianli Yue   +6 more
wiley   +1 more source

Microbial metabolites in tumor epigenetic regulation

iMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Ensiling and Fermentation of Rice Hulls With Ruminal Fluid for Medium‐Chain Carboxylate Production

Asia-Pacific Journal of Chemical Engineering, Volume 21, Issue 1, January/February 2026.
ABSTRACT Large quantities of rice hulls are common at milling sites in Nigeria. They are a by‐product of rice processing and can contribute to environmental degradation if not properly managed. In this study, rice hulls were pretreated by ensiling at ambient temperature and then used as substrate for medium‐chain carboxylates (MCCs) production ...
Jerome Undiandeye, Silas Kiman, Ebenezer Leke Odekanle, Peter Anyin   +3 more
wiley   +1 more source

Comparative Analysis of the Effects of Mogroside V, Epigallocatechin Gallate, and Resveratrol on Growth Performance, Blood Parameters, Rumen Microbiota, and Short‐Chain Fatty Acid Metabolism in Heat‐Stressed Hu Sheep

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Comparative effects of Mogroside V, EGCG, and resveratrol in heat‐stressed Hu sheep. ABSTRACT Hu sheep are highly prized for their tender meat, but heat stress (HS) caused by the high temperature and humidity in southern China severely impacts their performance.
Yirong Wei, Jun Lu, Shaoqiang Wu, Zhihua Mo, Haien He, Yulong Shen, Jianwei Zou, Cheng Xing, Yanna Huang, Qinyang Jiang   +9 more
wiley   +1 more source