Results 161 to 170 of about 40,616 (253)

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

Neurourology and Urodynamics, Volume 45, Issue 5, Page 929-936, June 2026.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk, Michel Wyndaele, Ana Charrua, Christopher Fry, Paul Abrams, Gommert A. van Koeveringe, Anthony J. Kanai, Marcus J. Drake   +7 more
wiley   +1 more source

Quantitative profiling of capsaicin content in seven chili pepper cultivars using optimized HPLC. [PDF]

Front Plant Sci
Pandey P, Huo J, Zhang Q.
europepmc   +1 more source

Capsaicin ameliorates glycemic levels via gut microbiota-derived 5-aminolevulinic acid in mice. [PDF]

Microbiome
Fang Q, Huang S, Zhang C, Li M, Ye Z, Guo H, Xiao M, Wang S, Yu L, Zhang H, Zhao J, Tian F, Chen W, Zhai Q.   +13 more
europepmc   +1 more source

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner, Alina Ilie, Léo Han, Annie Boucher, Rebecca Anne McKinney, Reza Sharif‐Naeini, John Orlowski   +6 more
wiley   +1 more source

Loading Capsaicin onto Lipid Bilayers: A Molecular Dynamics Study. [PDF]

ACS Omega
Kerdkaen N, Nisoh N, Kitjanon J, Dias C, Karttunen M, Wong-Ekkabut J.   +5 more
europepmc   +1 more source

Clarifying Terminology in Chronic Cough: The Evolving Role of Cough Hypersensitivity Syndrome

The Clinical Respiratory Journal, Volume 20, Issue 6, June 2026.
This review clarifies the definitions and relationships among ICC, UCC, and RCC, and introduces cough hypersensitivity syndrome (CHS) as an important pathophysiological framework for understanding chronic cough. Within this framework, CHS provides a mechanism‐based perspective that may complement existing terminology, guide future research, and improve
Zihang Wang, Yaxing Zhou, Yingchun Ren, Jiaying Yuan, Tongyangzi Zhang, Shengyuan Wang, Wanzhen Li, Li Yu, Xianghuai Xu   +8 more
wiley   +1 more source

Cerebrospinal Fluid and Plasma Concentrations of Atogepant in Humans

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT The aim of this study was to determine the cerebrospinal fluid (CSF) to plasma concentration ratio of atogepant. Healthy adult participants (N = 28) were enrolled into this phase 1, open‐label study and received atogepant 60 mg once daily for 8 days. Steady‐state atogepant concentrations were determined from CSF samples collected on Day 6 at 2
Ramesh R. Boinpally, Joel M. Trugman
wiley   +1 more source

Effectiveness of the P2X₃ Antagonist Gefapixant for Refractory Atopic Cough: A Retrospective Cohort Study. [PDF]

J Asthma Allergy
Ishiura Y, Nomura S, Ohkura N, Hara J, Fujimura M, Ito T.   +5 more
europepmc   +1 more source

Effects of capsaicin and monensin on ruminal fermentation, intake, nutrient digestibility, and ruminal dynamics of grazing bulls. [PDF]

Arch Anim Breed
Santiago MR, Madrigal-Valverde M, Silva APGD, Araújo MLGML, Carvalho GGP, Pina DDS, Pires AJV, Menezes AA, Dantas LL, Chaves MLO, Brant LMS, Freitas Júnior JE.   +11 more
europepmc   +1 more source

Kidney supportive care in Australia and New Zealand: an Australian and New Zealand Society of Nephrology (ANZSN) and Australian and New Zealand Society of Palliative Medicine (ANZSPM) guidance document

Internal Medicine Journal, Volume 56, Issue S2, Page 4-48, June 2026.
The purpose of this document is to provide a summary of the current expert opinion and recent literature for clinicians, Indigenous health workers and patient advocates interested in Kidney Supportive Care (KSC) in Australia and New Zealand. Our purpose is not to duplicate the recently released International Society of Nephrology (ISN) KSC/Conservative
Kathryn Ducharlet, Frank Brennan, Rajesh Raj, Charlotte Ogivly, Elizabeth Stallworthy, Kelly Chenlei Li, Alice Kennard, Selina Bob, Nicole Scholes‐Robertson, Riona Pais, Jenny Chen, Kirsten Hepburn, Lisa Jeffs, Ilse Berquier, Jacquelyne Hughes, Christine Sanderson, Sara Rendo, Gowri Raman, Erin Vaughan, Sarah So, Curtis Walker, Suetonia Green, Rangimarie Nadia Glavish, Mark Brown   +23 more
wiley   +1 more source