In Silico and In Vitro Investigation of Apoptosis-Mediated Antiproliferative Activity of Capsaicin and Alpha-Lipoic Acid Against Prostate Cancer Cells. [PDF]
Meral O +9 more
europepmc +1 more source
The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley +1 more source
Loss of TRPV1 may shift capsaicin response from MAPK-CASC11-MYC protection to mitochondrial apoptosis in glioblastoma U87 cells. [PDF]
Chinreddy SR +7 more
europepmc +1 more source
ABSTRACT Object To explore the clinical efficacy of a narrow‐band intense pulsed light (DPL) with different energy density in the treatment of erythematotelangiectatic rosacea (ETR). Methods A retrospective study was conducted on patients diagnosed with erythema telangiectatic rosacea who received 5 DPL treatment sessions in the laser cosmetology ...
Lingling Yang +2 more
wiley +1 more source
Modulation of corneal sensory processing and pain responses by dry eye and corneal wounding. [PDF]
Yaman E +11 more
europepmc +1 more source
ABSTRACT Background Effective and safe skin penetration enhancers are highly valuable for improving the efficacy of topical drug and cosmetic formulations. Objective This study aimed to develop and validate novel synergistic combinations of tetrahydropiperine (THP), 2,3‐butanediol (2,3‐BD), and hydrolyzed glycosaminoglycans (hGAGs) as effective skin ...
Bei Wang +4 more
wiley +1 more source
Xenin-25 improves indomethacin-induced acute gastric injury in rats. [PDF]
Arabacı Tamer S +3 more
europepmc +1 more source
Neural mechanisms of cough: insights from multimodal magnetic resonance imaging-a narrative review. [PDF]
Liu X +7 more
europepmc +1 more source
Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction. [PDF]
Gao X +20 more
europepmc +1 more source
Capsaicin Mitigates Insulin Resistance-Driven Prostate Hyperplasia Via IGF-1 Signalling Modulation in HFD + STZ Rat Model. [PDF]
Kotaru M, Ranjan Das N.
europepmc +1 more source

