Results 121 to 130 of about 71,965 (172)

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Understanding of endo/lysosomal escape of nanomaterials in biomedical application

Smart Molecules, EarlyView.
This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang, Haoyu Li, Chen Chen, Zhihui Liang   +3 more
wiley   +1 more source

Biohybrid Microrobots Based on Jellyfish Stinging Capsules and Janus Particles for In Vitro Deep‐Tissue Drug Penetration

Small Science, EarlyView.
This study introduces a biohybrid microrobot utilizing jellyfish‐stinging capsules as nanoinjectors, integrated onto Janus particles. Controlled by magnetic and electric fields, these microrobots achieve deep tissue penetration and precise drug delivery.
Sinwook Park, Noga Barak, Tamar Lotan, Gilad Yossifon   +3 more
wiley   +1 more source

Enhanced Discriminability of Viral Vectors in Viscous Nanopores

Small Methods, EarlyView.
Solid‐state nanopore sensing in high‐viscosity organic‐water mixture enables enhanced discriminability of full, intermediate, and empty AAV vectors at the single particle level, paving the way for enhanced quality control of AAV products for their wide applications in gene therapy.
Makusu Tsutsui, Yuji Tsunekawa, Mikako Wada, Akihide Arima, Azusa Onodera, Masumi Nishina, Miho Nagoya, Yoshinobu Baba, Tomoji Kawai, Takashi Okada   +9 more
wiley   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Construction of digital databases of crop‐growing calendars for Japanese crops

Ecological Research, EarlyView.
This study digitized the Japanese government's paper‐based statistical data on crop‐growing calendars, creating a comprehensive database. The target crops encompassed a cumulative total of 157 different crops across Japan. The database is expected to enhance accessibility to this information, improve understanding of agroecosystems, address pest ...
Atsushi Wakai, Eri Tanaka, Gen Sakurai
wiley   +1 more source

On the field: Race, gender and sports in colonial Ghana

Gender &History, EarlyView.
Abstract This article analyses Ghanaian women's sport practice from the late nineteenth century to the late 1950s, from games intertwined with displays of colonial authority to school competitions, physical education and tennis. The article argues that their performances played with changing categorisations of African girlhood and womanhood, especially
Claire Nicolas
wiley   +1 more source

Differences in within‐plant oviposition preferences and immature survival between Orius predators and the importance of spatial availability of prey

Insect Science, EarlyView.
Orius predators oviposit endophytically, and plant characteristics play an important role in their oviposition choices. In this study, we show that oviposition preferences differ between species, and that these differences may correlate with juvenile performance.
Angelos Mouratidis, Christiaan Bootsma, Marcel Dicke, Gerben J. Messelink   +3 more
wiley   +1 more source

Identification and characterisation of Zucchini yellow fleck virus and a novel Nepovirus from next‐generation sequencing of mixed virus infections in cucumbers (Cucumis sativus) from Crete

Annals of Applied Biology, Volume 186, Issue 3, Page 248-261, May 2025.
High‐throughput sequencing from cucumber leaf samples collected in Crete, Greece, revealed mixed infections including a cucumber‐infecting isolate of Zucchini yellow fleck virus and a novel nepovirus, provisionally named cucumber nepovirus A (CuNVA).
Anthony James, Nikoleta Kryovrysanaki, Christos Andronis, Polyxeni G. Pappi, Kriton Kalantidis, Konstantina Katsarou   +5 more
wiley   +1 more source