Results 101 to 110 of about 214,858 (192)

Residues 27T and 297A in VP2 contribute to the enhanced replication and pathogenicity of raccoon dog parvovirus

Journal of Virology
Raccoon dog parvovirus (RDPV) is a highly contagious pathogen causing severe hemorrhagic enteritis that is fatal in young raccoon dogs. Since 2016, epidemiological investigations have documented recurrent outbreaks of RDPV, exhibiting heightened ...
Liwen Xu, Wenyu Cao, Yawen Liu, Bo Hu, Chengqi Zhang, Shuangshuang Li, Jiajia Liu, Jianhai Fu, Zichuang Zhang, Yajie Sun, Guanyu Zhao, Xiaoyu Deng, Rongguang Lu, Xue Bai   +13 more
doaj   +1 more source

HIV-1 infection regulates gene expression by altering alternative polyadenylation correlated with CPSF6 and CPSF5 redistribution

mBio
HIV-1 viral core transport to the nucleus, an early infection event, triggers the redistribution of cleavage and polyadenylation specificity factors (CPSF) 5 and CPSF6 to nuclear speckles, forming puncta-like structures.
Charlotte Luchsinger, Annie Zhi Dai, Hari Yalamanchili, Aiswarya Balakrishnan, Kai-Lieh Huang, Cinzia Bertelli, Bin Cui, Ramon Lorenzo-Redondo, Eric J. Wagner, Felipe Diaz-Griffero   +9 more
doaj   +1 more source

The apical region of the herpes simplex virus major capsid protein promotes capsid maturation

, 2018
The herpesvirus capsid assembles in the nucleus as an immature procapsid precursor built around viral scaffold proteins. The event that initiates procapsid maturation is unknown, but it is dependent upon activation of the VP24 internal protease. Scaffold
James F. Conway, Laura L. Ruhge, Alexis G. E. Huet, Gregory A. Smith   +3 more
core   +1 more source

Structures of HIV-1 capsid, hexamer, pentamer, and capsid protein.

, 2018
(A) The whole structure of an HIV-1 capsid. Hexamers and pentamers are colored light-orange and red, respectively. (D) Structure of the capsid protein. A hexamer structure is shown in (B) the top view and (E) the front view. A pentamer structure is shown
Hyuntae Na (814472), Guang Song (733747)
core   +1 more source

From the Cytoplasm into the Nucleus—Hepatitis B Virus Travel and Genome Repair

Microorganisms
Hepatitis B virus (HBV) is a major global health concern, affecting millions of people worldwide. HBV is part of the hepadnaviridae family and one of the primary causes of acute and chronic liver infections, leading to conditions such as cirrhosis and ...
Johan Ringlander, Gustaf E. Rydell, Michael Kann   +2 more
doaj   +1 more source

HIV-1 Capsid Rapidly Induces Long-Lived CPSF6 Puncta in Non-Dividing Cells, but Similar Puncta Already Exist in Uninfected T-Cells

Viruses
The HIV-1 capsid (CA) protein forms the outer shell of the viral core that is released into the cytoplasm upon infection. CA binds various cellular proteins, including CPSF6, that direct HIV-1 integration into speckle-associated domains in host chromatin.
Anabel Guedán, Megan Burley, Eve R. Caroe, Kate N. Bishop   +3 more
doaj   +1 more source

Self-assembled Artificial Viral Capsid Decorated with Gold Nanoparticles [PDF]

The decoration of a peptide-based artificial viral capsid with gold nanoparticles (AuNPs) is reported. β-Annulus GGGCG-bearing peptide as a binding site of AuNPs self-assembled into nanocapsules with a diameter of 50 nm.
Matsuura, Kazunori, Ueno, Genki, 100000881, 4763, 60283389, 27315, Fujita, Seiya, 27316, 27317, 27318   +9 more
core   +1 more source

Stoichiometric Binding of Cyclophilin-A to The HIV-1 Capsid Modulates Its Mechanoelastic Properties. [PDF]

Small
Rey JS, Bryer AJ, Perilla JR.
europepmc   +1 more source

DNA ejection and AAV capsid degradation under thermal stress: Insights from CDMS and native digestion strategies. [PDF]

Mol Ther Adv
Du C, Tang S, Nie S, Yan Y, Cotham VC, Shi W, Zhao Y, Lai KY, Zhi L, Luo L, Cao Y, Wang S, Liu D, Shameem M, O'Grady G, Liu N, Rosconi MP, Pyles EA, Wang S, Li N.   +19 more
europepmc   +1 more source

Small viruses reveal bidirectional evolution between HK97-fold viruses and encapsulins via procapsids. [PDF]

Nat Commun
Aguilar A, Miranda Perez I, Nadel O, Nayfach S, Ruiz Pestana L, Segall AM, Rohwer FL, Roux S, White S, Luque A.   +9 more
europepmc   +1 more source