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Impact of multiplicity of infection and baculovirus co-infection ratio on recombinant adeno-associated virus vector production in insect cells. [PDF]
Schrama M +8 more
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Nuclear pore passage of the HIV capsid is driven by its unusual surface amino acid composition. [PDF]
Fu L +5 more
europepmc +1 more source
Characterization of a Sabin-like type 2/3 recombinant poliovirus with a triple nucleotide deletion in the VP1 region isolated from sewage. [PDF]
Lin J +16 more
europepmc +1 more source
Unravelling the dynamics of the maturation protein in MS2 bacteriophage via molecular simulations. [PDF]
Masirevic S +6 more
europepmc +1 more source
A fully synthetic Golden Gate assembly system for engineering a <i>Pseudomonas aeruginosa</i> phiKMV-like phage. [PDF]
Sikkema AP +13 more
europepmc +1 more source
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Current HIV Research, 2003
HIV Gag assembly is the first and most essential step in the formation of virus particles. Following protein synthesis, Gag relocates from ribosomes and forms a virus particle at the plasma membrane, using host factors and machinery. Early studies focused on mapping the regions within Gag required for assembly and identified three distinct domains (M ...
openaire +2 more sources
HIV Gag assembly is the first and most essential step in the formation of virus particles. Following protein synthesis, Gag relocates from ribosomes and forms a virus particle at the plasma membrane, using host factors and machinery. Early studies focused on mapping the regions within Gag required for assembly and identified three distinct domains (M ...
openaire +2 more sources
2018
The retrovirus capsid core is a metastable structure that disassembles during the early phase of viral infection after membrane fusion. The core is intact and permeable to essential nucleotides during reverse transcription, but it undergoes disassembly for nuclear entry and genome integration.
Wei, Zhang +2 more
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The retrovirus capsid core is a metastable structure that disassembles during the early phase of viral infection after membrane fusion. The core is intact and permeable to essential nucleotides during reverse transcription, but it undergoes disassembly for nuclear entry and genome integration.
Wei, Zhang +2 more
openaire +2 more sources
Deep diversification of an AAV capsid protein by machine learning
Nature Biotechnology, 2021D. Bryant +8 more
semanticscholar +1 more source
2008
Coat proteins (CPs) of all plant viruses have an early function in disassembly of parental virus and a late function in assembly of progeny virus. Depending on the virus, however, CPs may play a role in many steps of the infection cycle in between these early and late functions.
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Coat proteins (CPs) of all plant viruses have an early function in disassembly of parental virus and a late function in assembly of progeny virus. Depending on the virus, however, CPs may play a role in many steps of the infection cycle in between these early and late functions.
openaire +2 more sources
C&EN Global Enterprise, 2017
For most of his career at Gilead Sciences, medicinal chemist Winston Tse has lived and breathed one thing. While his peers at other companies hopped from project to project, Tse has spent the past decade obsessing over a single target: the HIV capsid. HIV’s capsid is a complex, protein-rich shell that protects the genetic payload the virus is trying to
openaire +1 more source
For most of his career at Gilead Sciences, medicinal chemist Winston Tse has lived and breathed one thing. While his peers at other companies hopped from project to project, Tse has spent the past decade obsessing over a single target: the HIV capsid. HIV’s capsid is a complex, protein-rich shell that protects the genetic payload the virus is trying to
openaire +1 more source

