Results 21 to 30 of about 113,851 (300)

A role for LHC1 in higher order structure and complement binding of the Cryptococcus neoformans capsule.

open access: yesPLoS Pathogens, 2014
Polysaccharide capsules are important virulence factors for many microbial pathogens including the opportunistic fungus Cryptococcus neoformans. In the present study, we demonstrate an unusual role for a secreted lactonohydrolase of C.
Yoon-Dong Park   +13 more
doaj   +1 more source

Staphylococcus aureusCapsular Polysaccharides [PDF]

open access: yesClinical Microbiology Reviews, 2004
SUMMARYSerotype 5 and 8 capsular polysaccharides predominate among clinical isolates ofStaphylococcus aureus.The results of experiments in animal models of infection have revealed that staphylococcal capsules are important in the pathogenesis ofS. aureusinfections.
Katherine, O'Riordan, Jean C, Lee
openaire   +2 more sources

Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity

open access: yesCommunications Biology, 2023
Bacterial capsular polysaccharides are important vaccine immunogens. However, the study of polysaccharide-specific immune responses has been hindered by technical restrictions.
Dennis Hoving   +14 more
doaj   +1 more source

Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus

open access: yesNature Communications, 2019
The cell wall of Gram-positive bacteria consists of peptidoglycan modified with other polymers, such as the capsular polysaccharide. Here, the authors reconstitute the biosynthesis of capsular polysaccharide and elucidate its interplay with the cell wall
Marvin Rausch   +14 more
doaj   +1 more source

Transport of Streptococcus pneumoniae capsular polysaccharide in MHC Class II tubules. [PDF]

open access: yesPLoS Pathogens, 2007
Bacterial capsular polysaccharides are virulence factors and are considered T cell-independent antigens. However, the capsular polysaccharide Sp1 from Streptococcus pneumoniae serotype 1 has been shown to activate CD4(+) T cells in a major ...
Tom Li Stephen   +12 more
doaj   +1 more source

Synthesis and Preliminary Immunological Evaluation of a Pseudotetrasaccharide Related to a Repeating Unit of the Streptococcus pneumoniae Serotype 6A Capsular Polysaccharide

open access: yesFrontiers in Molecular Biosciences, 2021
2-Aminoethyl glycoside of the pseudotetrasaccharide α-d-Glcp-(1→3)-α-l-Rhap-(1→3)-d-Rib-ol-(5-P-2)-α-d-Galp corresponding to a repeating unit of the Streptococcus pneumoniae type 6A capsular polysaccharide has been synthesized.
Elena V. Sukhova   +5 more
doaj   +1 more source

In vivo role of capsular polysaccharide in Mycoplasma mycoides [PDF]

open access: yes, 2019
Capsular polysaccharides have been confirmed to be an important virulence trait in many gram-positive and gram-negative bacteria. Similarly, they are proposed to be virulence traits in minimal Mycoplasma that cause disease in humans and animals.
Schieck, Elise G.   +15 more
core   +2 more sources

Anti-biofilm activity of a polysaccharide from marine sponge associated Bacillus licheniformis [PDF]

open access: yes, 2011
Secondary metabolites ranging from furanone to exo-polysaccharides have been suggested to have anti-biofilm activity in various recent studies. Among these,Escherichia coli group II capsular polysaccharides were shown to inhibit biofilm formation in a ...
S. M. Abu, Sayem
core   +1 more source

Characterization of porcine dendritic cell response to Streptococcus suis

open access: yesVeterinary Research, 2011
Streptococcus suis is a major swine pathogen and important zoonotic agent causing mainly septicemia and meningitis. However, the mechanisms involved in host innate and adaptive immune responses toward S. suis as well as the mechanisms used by S.
Lecours Marie-Pier   +6 more
doaj   +1 more source

Non-capsular based immunization approaches to prevent Streptococcus pneumoniae infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Streptococcus pneumoniae is a Gram-positive bacterium and the leading cause of bacterial pneumonia in children and the elderly worldwide. Currently, two types of licensed vaccines are available to prevent the disease caused by this pathogen: the 23 ...
Pedro H. Silva   +14 more
doaj   +1 more source

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