Results 51 to 60 of about 134,019 (273)

Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges

Advanced Robotics Research, EarlyView.
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley   +1 more source

Induction of Susceptibility to Disseminated Infection with IgA1 Protease-Producing Encapsulated Pathogens Streptococcus pneumoniae, Haemophilus influenzae Type b, and Neisseria meningitidis

mBio, 2022
Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae are the principal causes of bacterial meningitis. It is unexplained why only occasional individuals develop invasive infection, while the vast majority remain healthy and ...
Mogens Kilian, Steffen Husby, Jesper Andersen, Zina Moldoveanu, Uffe B. Skov Sørensen, Jesper Reinholdt, Hervé Tettelin   +6 more
doaj   +1 more source

Occurrence of L-iduronic acid and putative D-glucuronyl C5-epimerases in prokaryotes [PDF]

, 2011
Glycosaminoglycans (GAGs) are polysaccharides that are typically present in a wide diversity of animal tissue. Most common GAGs are well-characterized and pharmaceutical applications exist for many of these compounds, e.g. heparin and hyaluronan.
Kengen, S.W.M., Servé W. M. Kengen, Oost, J., van der, Raedts, J.G.J., John van der Oost, John Raedts   +5 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Chemical shift assignments of the type c capsular polysaccharide purified from PYKK60.

, 2016
Chemical shift assignments of the type c capsular polysaccharide purified from PYKK60.
Kimberly F. Starr (464984), Pablo Yagupsky (160677), L. Scott Forsberg (3227367), Eric A. Porsch (464985), Radnaa Naran (3227364), Uri Amit (3227370), Patrick C. Seed (192918), Christian Heiss (446842), Parastoo Azadi (223686), Joseph W. St. Geme III (248201)   +9 more
core   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Distribution of clonal complexes (CC) and capsular polysaccharide (CP) genotypes by ward source.

, 2019
Distribution of clonal complexes (CC) and capsular polysaccharide (CP) genotypes by ward source.
Naglaa Mohamed (1378089), Bing Cai (151199), Shite Sebastian (6205322), Matthew T. G. Holden (130258), Annaliesa S. Anderson (477401), Robert G. K. Donald (6205325), Guy Singh (2525419), Yekaterina Timofeyeva (6205316), Paul Liberator (66366), C. Hal Jones (696213), Dorota Jamrozy (4269490), Eduardo Rojas (696212), Kathrin U. Jansen (477400), Isaac Thomsen (6205328), Li Hao (137452), Julio Hawkins (6205319), Ingrid L. Scully (4436452), Sharon J. Peacock (35782), Julian Parkhill (30393), Natalie C. Silmon de Monerri (5625383), C. Buddy Creech (748289)   +20 more
core   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

High cell density cultivation of Escherichia coli K4 in a microfiltration bioreactor: a step towards improvement of chondroitin precursor production

Microbial Cell Factories, 2011
Background The bacteria Escherichia coli K4 produces a capsular polysaccharide (K4 CPS) whose backbone is similar to the non sulphated chondroitin chain.
De Rosa Mario, Catapano Angela, De Rosa Mario, Cimini Donatella, Restaino Odile, Schiraldi Chiara   +5 more
doaj   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

Advanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan, Soham Maity, Herbert Kavunja, Yuvarani Murali, Ting‐An Chen, Chang‐xin Huo, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source