Results 81 to 90 of about 113,851 (300)

Capsular Polysaccharide Expression in Commensal Streptococcus Species: Genetic and Antigenic Similarities to Streptococcus pneumoniae

mBio, 2016
Expression of a capsular polysaccharide is considered a hallmark of most invasive species of bacteria, including Streptococcus pneumoniae, in which the capsule is among the principal virulence factors and is the basis for successful vaccines ...
Uffe B. Skov Sørensen, Kaihu Yao, Yonghong Yang, Hervé Tettelin, Mogens Kilian   +4 more
doaj   +1 more source

Structure and In Vitro Bioactivity against Cancer Cells of the Capsular Polysaccharide from the Marine Bacterium Psychrobacter marincola

Marine Drugs, 2020
Psychrobacter marincola KMM 277T is a psychrophilic Gram-negative bacterium that has been isolated from the internal tissues of an ascidian Polysyncraton sp. Here, we report the structure of the capsular polysaccharide from P.
Maxim S. Kokoulin, Alexandra S. Kuzmich, Lyudmila A. Romanenko, Irina V. Chikalovets, Oleg V. Chernikov   +4 more
doaj   +1 more source

Revised structure of the polysaccharide from Acinetobacter baumannii LUH5551 assigned as the K63 type capsular polysaccharide

K63 capsular polysaccharide produced by Acinetobacter baumannii isolate LUH5551 (previously designated isolate O24) was re-examined using sugar analysis, Smith degradation, and one- and two-dimensional 1H and 13C NMR spectroscopy.
Kasimova, AA, Perepelov, AV, Shashkov, AS, Knirel, YA, Arbatsky, NP, Shneider, MM, Hall, RM, Kenyon, JJ, Popova, AV   +8 more
core   +1 more source

A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children. [PDF]

, 2010
BACKGROUND: The emergence of drug resistant typhoid fever is a major public health problem, especially in Asia. An oral single dose typhoid vaccine would have major advantages.
Schultsz, C, To, S.D., Vinh Chau Nguyen Van, Dolecek, C., Thi Diem Ha Tran, Dolecek, Christiane, Nguyen, V.M.H., Van Vinh Chau Nguyen, Upton Anthony, Nguyen, T.D., Thi Dung Nguyen, James P May, Marques, F, Nguyen, T.T., Schultsz, Constance, Glover, Clare, Upton, A., Nguyen, Thi Cam Binh, Stockwell, E, Hoang Nguyen Van Minh, Schultsz, C., Farrar, Jeremy, Upton, A, Glover, C., Van Minh Hoang Nguyen, Nguyen, Thanh Truong, Filipe Marques, Nguyen, TCB, James P. May, Pham Van Toi, James I. Campbell, Stockwell, E., Pham, Van Toi, Elaine Stockwell, Nga Tran Thi Thu, Ninh, TTV, Tran, T.D.H., May, James P, James I Campbell, To, Song Diep, Nguyen, T.C.B., Toi Pham Van, Tran, Thi Thu Nga, May, J.P., Tran, TTN, Budhram, R., Tran, T.T.N., Simmons, Cameron P, Van Toi Pham, Tran, N.B.C., Lam, W., Glover Clare, Campbell, J.I., Marques, F., Ha Tran Thi Diem, Bich Chau Tran Nguyen, Tran, TDH, Nguyen, VVC, Campbell, JI, Ninh Thi Thanh Van, To, SD, Schultsz Constance, Dougan, Gordon, Ninh, Tran, Lam, Winnie, Nguyen, V.V.C., Campbell James I., Farrar Jeremy, Dolecek, C, Upton, Anthony, Christiane Dolecek, Cameron P. Simmons, Simmons, Cameron, Stockwell, Elaine, Tran, Tinh Hien, Ninh, Thi Thanh Van, Nguyen Thi Cam Binh, Budhram, Ronald, Nguyen Thi Dung, Dung Nguyen Thi, Hien Tran Tinh, Cao, Thu Thuy, Van Ninh Thi Thanh, Cao, T.T., Simmons, Cameron P., Constance Schultsz, Tran, NBC, Tran Tinh Hien, Stockwell Elaine, Nguyen, Van Minh Hoang, Dolecek Christiane, Tran, TH, Lam Winnie, Campbell, James I, Nguyen, Van Vinh Chau, Tran Thi Diem Ha, Nguyen, Thi Dung, Winnie Lam, Gordon Dougan, May James P., Farrar, J, Nguyen Bich Chau Tran, Nguyen, TC, Nguyen, TD, Jeremy Farrar, Tran, TT, Cao Thu Thuy, Tinh Hien Tran, Thi Thanh Van Ninh, Budhram, R, Pham, V.T., Thu Thuy Cao, Simmons, C.P., Nguyen, TT, Glover, C, Tran, TD, Thuy Cao Thu, Ninh, TT, Simmons, CP, May, James P., Dougan, G., Ronald Budhram, Pham, V.M., Thi Cam Binh Nguyen, Pham, Van Minh, Lam, W, Thanh Truong Nguyen, Nguyen Van Minh Hoang, Farrar, J., Van Minh Pham, Tran, Nguyen Bich Chau, Thi Thu Nga Tran, Song Diep To, Nguyen Thanh Truong, Dougan Gordon, Pham Van Minh, Cao, TT, Clare Glover, Nguyen Van Vinh Chau, To Song Diep, Ninh, T.T.V., Tran, NB, Nguyen, MV, Budhram Ronald, Tran Nguyen Bich Chau, Marques, Filipe, Campbell, James I., Tran, Thi Diem Ha, Simmons Cameron P., Binh Nguyen Thi Cam, Tran, T.H., Cameron P Simmons, Pham, VM, Nguyen, VM, Tran Thi Thu Nga, Marques Filipe, Pham, VT, Nguyen, VV, Minh Pham Van, May, JP, Dougan, G, Anthony Upton, Truong Nguyen Thanh   +162 more
core   +2 more sources

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Structures of some bacterial polysaccharides with focus on pneumococcal polysaccharides and their associated C-polysaccharide

, 1998
This thesis describes the chemical structures of the capsular polysaccharides from Streptococcus pneumoniae types 18B, 32F, and 32A. The structure of the pneumococcal common antigen, C-polysaccharide, from a non-capsulated pneumococcal strain, CSR SCS2 ...
Camilla Karlsson (13749555)
core   +1 more source

In‐line Raman spectroscopy real‐time glucose prediction method for commercial pneumococcal vaccine drug substance fermentation manufacturing process control

Biotechnology Progress, EarlyView.
Abstract Traditional off‐line analysis methods to quantify residual metabolite concentrations in a drug substance fermentation process consume valuable time, require costly resources, and demand potentially hazardous manual operations when working with pathogenic biological organisms.
Griffin P. Thomas, Brian C. Marks, Barbara B. Alvarado‐Hernandez, Matthew Woodling, James O'Connor, Roberto Ortiz, John Higgins, Jon Shanter   +7 more
wiley   +1 more source

Phosphoenolpyruvate phosphotransferase system components positively regulate Klebsiella biofilm formation

Journal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Klebsiella pneumoniae is one of the leading causes of device-related infections (DRIs), which are associated with attachment of bacteria to these devices to form a biofilm.
Yu-Tze Horng, Chi-Jen Wang, Wen-Ting Chung, Huei-Jen Chao, Yih-Yuan Chen, Po-Chi Soo   +5 more
doaj   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Microfluidic production of monodisperse food‐additive polymer capsules for biological applications

Droplet, EarlyView.
Monodisperse TGPR polymer capsules are generated via a robust microfluidic approach exploiting droplet interface transfer across the oil‒water interface. Unlike lipid vesicles, these capsules offer high thermal stability and biocompatibility. They successfully demonstrated utility as robust bioreactors for in‐capsule PCR and bacterial cultivation ...
Yuki Gondo, Daiki Miyashita, Kazu Toyota, Mamiko Tsugane, Taro Toyota, Hiroaki Suzuki   +5 more
wiley   +1 more source