Results 41 to 50 of about 430,330 (312)

A Narrative Review of the W, X, Y, E, and NG of Meningococcal Disease: Emerging Capsular Groups, Pathotypes, and Global Control

open access: yesMicroorganisms, 2021
Neisseria meningitidis, carried in the human nasopharynx asymptomatically by ~10% of the population, remains a leading cause of meningitis and rapidly fatal sepsis, usually in otherwise healthy individuals.
Yih-Ling Tzeng, David S. Stephens
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Capsule Thickness, Not Biofilm Formation, Gives Rise to Mucoid Acinetobacter baumannii Phenotypes That are More Prevalent in Long-Term Infections: A Study of Clinical Isolates from a Hospital in China

open access: yesInfection and Drug Resistance, 2020
Lihua Hu,1,* Yue Shi,2,3,* Qingye Xu,2,3 Linghong Zhang,2,3 Jintao He,2,3 Yan Jiang,2,3 Lilin Liu,2,3 Sebastian Leptihn,4 Yunsong Yu,2,3 Xiaoting Hua,2,3 Zhihui Zhou2,3 1Department of Critical Care Medicine, Hangzhou General Hospital of Chinese People ...
Hu L   +10 more
doaj  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Capsular polysaccharide determines the serotyping of Riemerella anatipestifer

open access: yesMicrobiology Spectrum, 2023
Riemerella anatipestifer (R. anatipestifer) is a Gram-negative pathogen that causes significant economic losses to the farming industry. The polysaccharides that determine serotype are well understood in other bacteria; they have not yet been fully ...
Yanling Liu   +18 more
doaj   +1 more source

Efficacy and Safety of Keluoxin Capsule in the Treatment of Diabetic Kidney Disease [PDF]

open access: green, 2021
Jingxin Zhou   +7 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

An experimental performance verification of continuous mixed P‐norm based adaptive asymmetrical fuzzy logic controller for single stage photovoltaic grid integration

open access: yesIET Renewable Power Generation
This paper deals with a new continuous mixed p‐norm (CMPN) based adaptive asymmetrical fuzzy logic controller (AAFLC) method for single stage grid integrated photovoltaic (PV) system as an inverter control strategy.
Neeraj Priyadarshi   +3 more
doaj   +1 more source

The qualitative determination of oseltamivir phosphate in Tamiflu® capsule by cyclic voltammetry [PDF]

open access: yesHemijska Industrija, 2011
A gold electrode was applied in the voltammetric determination of oseltamivir phosphate standard in 0.05 M NaHCO3. Oseltamivir phosphate as a standard and as a component of Tamiflu® capsule exhibited the identical cyclic voltammogram.
Avramov-Ivić Milka L.   +3 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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