Results 51 to 60 of about 677,582 (318)

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, Volume 19, Issue 7, Page 1968-1978, July 2025.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Rapid Capsular Antigen Immunoassay for Diagnosis of Inhalational Anthrax: Preclinical Studies and Evaluation in a Nonhuman Primate Model

mBio, 2022
Inhalational anthrax is a fatal infectious disease. Rapid and effective treatment is critically dependent on early and accurate diagnosis. Blood culture followed by identification and confirmation may take days to provide clinically relevant information.
Marcellene A. Gates-Hollingsworth, Cari B. Kolton, Alex R. Hoffmaster, Gabriel T. Meister, Addie E. Moore, Heather R. Green, Janice M. Pogoda, Segaran P. Pillai, Thomas R. Kozel   +8 more
doaj   +1 more source

Multifunctional Capsule‐in‐Capsules for Immunoprotection and Trimodal Imaging [PDF]

Angewandte Chemie, 2011
Type I diabetes mellitus (T1DM) is a T-cell-mediated autoimmune disease that results in destruction of insulin-producing β cells and subsequent hyperglycemia.[1,2] The current way of treating T1DM is insulin replacement therapy through repetitive injections of recombinant insulin.
Dian R. Arifin, Assaf A. Gilad, Heechul Kim, Naser Muja, Taeho Kim, Taeho Kim, Jeff W.M. Bulte, Jaeyun Kim, Aravind Arepally, Taeghwan Hyeon, Taeghwan Hyeon   +10 more
openaire   +3 more sources

Ferrofluidic solenoid [PDF]

, 1973
An electromechanical actuator for producing mechanical force and/or motion in response to electrical signals is disclosed. The actuator includes a ferromagnetic fluid and a coil which are contained within an elastomeric capsule.
Sabelman, E. E.
core   +1 more source

Head Capsule Widths as an Indicator of the Larval Instar of Codling Moth (Lepidoptera: Olethreutidae) [PDF]

, 2017
Head capsule width was a reliable indicator of larval instar in a strain of Michigan codling moths, Cydia pomonella. Head capsules were 0.33, 0.50, 0.82, 1.18 and 1.55 mm in width from first to fifth instar respectively.
Weitzner, Peter, Whalon, Mark E
core   +3 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, Volume 19, Issue 7, Page 2014-2037, July 2025.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

AGEs in human lens capsule promote the TGFβ2-mediated EMT of lens epithelial cells:Implications for age-associated fibrosis [PDF]

, 2016
Proteins in basement membrane (BM) are long-lived and accumulate chemical modifications during aging; advanced glycation end-product (AGE) formation is one such modification. The human lens capsule is a BM secreted by lens epithelial cells. In this study,
Glomb, Marcus, Gupta, Pankaj, Howell, Scott, Nagaraj, Ram, Raghavan, Cibin, Singh, Annapurna, Smith, Andrew, Smith, Dawn, Smuda, Mareen, Wormstone, Ian   +9 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Assembly for recovering a capsule Patent [PDF]

, 1964
Assembly for opening flight capsule stabilizing and decelerating flaps with reference to capsule ...
Lawson, B. D., Warren, A. P.
core   +1 more source