Results 71 to 80 of about 33,619 (260)

CapsProm: a capsule network for promoter prediction

open access: yesComputers in Biology and Medicine, 2022
Locating the promoter region in DNA sequences is of paramount importance in the field of bioinformatics. This is a problem widely studied in the literature, however, not yet fully resolved. Some researchers have presented remarkable results using convolution networks, that allowed the automatic extraction of features from a DNA chain.
Lauro Moraes   +3 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Smartphone Handwritten Circuits Solver Using Augmented Reality and Capsule Deep Networks for Engineering Education

open access: yesEducation Sciences, 2021
Resolving circuit diagrams is a regular part of learning for school and university students from engineering backgrounds. Simulating circuits is usually done manually by creating circuit diagrams on circuit tools, which is a time-consuming and tedious ...
Marah Alhalabi   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Capsule GAN Using Capsule Network for Generator Architecture

open access: yesCoRR, 2020
This paper presents Capsule GAN, a Generative adversarial network using Capsule Network not only in the discriminator but also in the generator. Recently, Generative adversarial networks (GANs) has been intensively studied. However, generating images by GANs is difficult. Therefore, GANs sometimes generate poor quality images.
Kanako Marusaki, Hiroshi Watanabe
openaire   +2 more sources

DeepCaps: Going Deeper With Capsule Networks [PDF]

open access: yes2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2019
Capsule Network is a promising concept in deep learning, yet its true potential is not fully realized thus far, providing sub-par performance on several key benchmark datasets with complex data. Drawing intuition from the success achieved by Convolutional Neural Networks (CNNs) by going deeper, we introduce DeepCaps1, a deep capsule network ...
Jathushan Rajasegaran   +5 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Biomedical document triage using a hierarchical attention-based capsule network

open access: yesBMC Bioinformatics, 2020
Background Biomedical document triage is the foundation of biomedical information extraction, which is important to precision medicine. Recently, some neural networks-based methods have been proposed to classify biomedical documents automatically. In the
Jian Wang   +5 more
doaj   +1 more source

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