Results 41 to 50 of about 262,883 (261)

Transmission Capacity Analysis for Vehicular Ad Hoc Networks

open access: yesIEEE Access, 2018
Traditional studies focused on the transmission capacity of vehicular ad hoc network (VANET) contains two deficiencies: the lack of a realistic model mimicking the behaviors of vehicles and the failure to consider the impacts from enhanced distributed ...
Xinxin He, Weisen Shi, Tao Luo
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Dynamic Car-Following Model With Jerk Suppression for Highway Autonomous Driving

open access: yesIEEE Access
This study proposes a dynamic safe car-following strategy that is based on dynamic adjustment of headway time with jerk suppression. Reinforcement learning models trained with this strategy result in enhanced safety and driving comfort, validated using ...
Ke Liu, Jing Ma, Edmund M.-K. Lai
doaj   +1 more source

Development of kinks in car-following models [PDF]

open access: yesPhysical Review E, 2017
Many car-following models of traffic flow admit the possibility of absolute stability, a situation in which uniform traffic flow at any spacing is linearly stable. Near the threshold of absolute stability, these models can often be reduced to a modified Korteweg-deVries (mKdV) equation plus small corrections.
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Modelling Drivers' Behaviour as a Crash Risk Reduction Process

open access: yesPromet (Zagreb), 2008
The evermore widespread use of microscopic traffic simulationin the analysis of road systems has refocused attention onsub models, including car-following and lane-changing models.In this research a microscopic model is developed whichcombines car ...
Seyyed Mohammad Sadat Hoseini   +1 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Critical Data Discovery for Self-Driving: A Data Distillation Approach

open access: yesApplied Sciences
Deep learning models have achieved significant progress in developing self-driving algorithms. Despite their advantages, these algorithms typically require substantial amounts of data for effective training.
Xiangyi Liao, Zhenyu Shou, Xu Chen
doaj   +1 more source

Preoperative C-Reactive Protein-to-Albumin Ratio Predicts Postoperative Pancreatic Fistula following Pancreatoduodenectomy: A Single-Center, Retrospective Study

open access: yesCurrent Oncology, 2022
Postoperative pancreatic fistula (POPF) following pancreatoduodenectomy (PD) is a potentially lethal complication, and it is clinically important to determine its risk preoperatively. Although C-reactive protein-to-albumin ratio (CAR) is reported to be a
Naotake Funamizu   +10 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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