Results 141 to 150 of about 11,024,988 (313)

Preventing trogocytosis by cathepsin B inhibition augments CAR T-cell function

Signal Transduction and Targeted Therapy
Chimeric antigen receptor (CAR) T-cell therapy has shown remarkable efficacy in cancer treatment. Nevertheless, most patients receiving CAR T cells relapse within 5 years of treatment. CAR-mediated trogocytosis (CMT) is a potential tumor escape mechanism
Kenneth A. Dietze, Kiet Nguyen, Aashli Pathni, Frank Fazekas, Wenxiang Sun, Ethan Rosati, Jillian M. Baker, Maday Galeana Figueroa, Etse Gebru, Daniel Yamoah, Rediet Mulatu, Alexander Wang, Aaron P. Rapoport, David H. Lum, Xiaoxuan Fan, Sabarinath V. Radhakrishnan, Djordje Atanackovic, Arpita Upadhyaya, Tim Luetkens   +18 more
doaj   +1 more source

Allogeneic reactions of pre-activated CAR T cells on target-negative cancer cells

T cells were isolated from 2 donor's PBMCs and transduced with HER2-CAR construct. The study evaluated the cytotoxic activity of HER2-CAR T cells against three cell lines: HER2-negative MDA cells and HER2-positive MDA-HER2 and MDA-HER2-231 cells.
Li, Artyom
core  

Revisión y ampliación acueducto de Madrid, Mosquera, Funza. Memorias de cálculo

, 1982
El presente diseño y revisión de los planos y obras construidas del acueducto regional Madrid-Mosquera-Funza han sido elaborados mediante la orden do trabajo impartida por la Corporación Autónoma Regional de la Sabana de Bogotá y de los Valles de Ubaté y
Corporación Autónoma Regional de Cundinamarca - CAR
core  

Transparent Perovskite Light‐Emitting Diodes with Conductive Oxide Top Electrodes

Advanced Materials, EarlyView.
Transparent perovskite light‐emitting diodes (TrPeLEDs) enable simultaneous display and transparency, expanding application possibilities. Using a metal oxide buffer layer and pulsed laser deposition, TrPeLEDs with diverse compositions and architectures are demonstrated.
Michele Forzatti, Sergio Martínez‐Saiz, Morena Cervino, Edoardo Stanzani, Sandra Jenatsch, Qingsen Zeng, Joo Sung Kim, Dong‐Hyeok Kim, Eojin Yoon, Tae‐Woo Lee, Daniel Tordera, Henk J. Bolink   +11 more
wiley   +1 more source

CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude

Journal of Translational Medicine
Background Chimeric antigen receptor (CAR) T cell therapy is associated with high risk of adverse events. Glucocorticoids (GCs) are cornerstone in the management of high-grade cytokine release syndrome (CRS) and immune effector cell-associated ...
Thomas Poiret, Sara Vikberg, Esther Schoutrop, Jonas Mattsson, Isabelle Magalhaes   +4 more
doaj   +1 more source

“Smelltronics”—From Gas to Smell Sensing

Advanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono, Tsunaki Takahashi, Jiangyang Liu, Haruka Honda, Zeng Jing, Wataru Tanaka, Takuro Hosomi, Takeshi Yanagida   +7 more
wiley   +1 more source

Acuerdo 59 de 1987

, 1987
Por el cual se expide la Reglamentación de los Cerros Orientales de Bogotá, la junta directiva de la Corporación Autónoma Regional de las Cuencas de los ríos Bogotá, Ubaté, y Suarez, CAR, en ejercicio de sus atribuciones legales, estatutarias, en ...
Corporación Autónoma Regional de Cundinamarca – CAR
core  

Resonant Domain Wall Dynamics in a Three‐Dimensional Magnetic Nano Double Helix

Advanced Materials, EarlyView.
3D magnetic nanostructures promise exciting possibilities for magnetization dynamics. However, experimental realizations remain scarce. In nanoprinted cobalt double helices, time‐resolved X‐ray microscopy reveals harmonic domain wall dynamics. Simulations identify the mode and additional higher‐frequency resonances, revealing a rich dynamic landscape ...
Pamela Morales‐Fernández, Iason Konstantinos‐Douveas, Claas Abert, Elina Zhakina, Sandra Ruiz‐Gómez, Claudia Fernández‐González, Luke Alexander Turnbull, Sebastian Wintz, Markus König, Simone Finizio, Markus Weigand, Naëmi Leo, Dieter Suess, Aurelio Hierro‐Rodríguez, Amalio Fernández‐Pacheco, Claire Donnelly   +15 more
wiley   +1 more source

Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?

Advanced Materials, EarlyView.
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley   +1 more source

Programa CAR - BID Distrito Sanitario Villapinzón - Chocontá

, 1994
Anteriormente tomábamos muchos recursos, los usábamos dejándolos prácticamente inservibles olvidándonos de que como seres vivos dependemos del aire, del suelo y sus minerales y de todas las formas de vida, puesto que éstos y otros elementos constituyen ...
Corporación Autónoma Regional de Cundinamarca - CAR, Baez, Danilo   +1 more
core