Results 191 to 200 of about 812,191 (301)

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Predictive markers for the efficacy of CAR T-cell therapy: the interplay between CAR T-cell fitness and systemic immunity. [PDF]

Blood Adv
Yoo KH, Szymura S, Dong Z, Kandel A, Cha SC, Kwak LW.   +5 more
europepmc   +1 more source

Universal Gripper for Industrial Manipulation With Enhanced Rigid Mechanics and Self‐Adaptable Fingers

Advanced Robotics Research, EarlyView.
An enhanced universal gripper combining rigid mechanics with self‐adaptable fingers is presented for industrial automation. The novel six‐bar linkage with integrated compliant pad eliminates mechanical interference while enabling passive shape adaptation.
Muhammad Usman Khalid, Nirmal Kumar Ravikumar, Mattia Frascio, Sumanth Nagalakunta, Alessandro Seitone, Benoît Lévesque, Alessandro Zanella, Matteo Zoppi   +7 more
wiley   +1 more source

To modify or not to modify: Rethinking mRNA design for CAR T cell engineering. [PDF]

Mol Ther Nucleic Acids
Thatte AS, Mitchell MJ.
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Junction opener enables CAR T cell treatment of solid tumors. [PDF]

Sci Rep
Reed SJ, Sharma S, Novák C, Kim J, Kim K, Niemi E, Korjeff N, Lieber A, Reed SG, Duthie MS, Carter D.   +10 more
europepmc   +1 more source

Highlighting Recent Progress in Fiber Energy Harvesters: From Working Principles to Future Perspectives

Advanced Science, EarlyView.
Fiber energy harvesters offer unprecedented flexibility and a unique capacity for integration into commercial textiles, overcoming the limitations of bulky and rigid conventional devices. This review summarizes recent advances in fiber‐based energy harvesting and provides strategic outlooks to accelerate technological progress in the field. ABSTRACT As
Hanhwi Jang, Junseong Ahn, Yongrok Jeong, Sohee Jeon, Soon Hyoung Hwang, Min‐Wook Oh, Jun‐Ho Jeong, Inkyu Park, Yeon Sik Jung   +8 more
wiley   +1 more source

Management of hematological toxicities after BCMA-directed CAR-T cell therapy. [PDF]

Blood Cancer J
Cook J, Gupta S, Abdallah N, Rees M, Graham C, Ng LS, Bansal R, De Menezes Silva Corraes A, Helms K, Warsame R, Dingli D, Gonsalves W, Kourelis T, Gertz M, Hayman S, Leung N, Kapoor P, Hwa L, Fonder A, Hobbs M, Bergsagel L, Yadav U, Wiedmeier-Nutor E, Chhabra S, Fonseca R, Ailawadhi S, Parrondo R, Kumar S, Lin Y.   +28 more
europepmc   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Universal high-sensitivity CAR T-cell monitoring by targeting linker sequences. [PDF]

Front Immunol
Schwingen NR, Meretuk L, Aigner M, Kretschmann S, Scholz JK, Gsottberger F, Harrer DC, Dingfelder J, Lutzny-Geier G, Kharboutli S, Mackensen A, Müller F, Völkl S.   +12 more
europepmc   +1 more source