Results 51 to 60 of about 393,681 (269)

Numerical Process Simulation Validation of a Light Electronic Enclosure in Compliance With Required High-Quality Standards by the Automotive Industry

Advances in Materials Science and Engineering
The EU has challenged automotive manufacturers to meet ambitious CO2 reduction targets. To achieve this goal, it is necessary to resort to all types of solutions, including car weight reduction.
Catia Araujo, Silvia Cruz, Ricardo Freitas, Susana Silva, Anibal Portinha, Pedro Bernando   +5 more
doaj   +1 more source

Transforming risk into resilience: a review of insurance strategies for sustainable shrimp aquaculture in India and beyond

Frontiers in Sustainable Food Systems
Shrimp is a key commodity constituting one-third of the global annual seafood trade of USD 171 billion (2024) constituting for approximately 25% of the agricultural trade.
Ravisankar T., Prasanna Kumar Patil, Geetha R., Sairam C. V., Kumaran M., Muralidhar M., Ananda Raja R., Kavibharathi S. M., Testimona A., Venkateswarlu Podili, Kuldeep K. Lal   +10 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Untargeted metabolomic profiling and genome mining of endophytic Stenotrophomonas maltophilia strain 3A reveal a rich source of bioactive secondary metabolites

Frontiers in Microbiology
The changing climate has posed several constraints in agricultural productivity. The losses from the diseases like bacterial wilt caused by Ralstonia solanacearum are a major threat to tomato cultivation, however, the management is still difficult.
Pramod Kumar Sahu, Krishna Nanda Dhal, Nakul Kale, Amrita Gupta, Nidhi Rai, Deepak Singla, Alok Kumar Srivastava   +6 more
doaj   +1 more source

Sensorless Speed Control with Initial Rotor Position Estimation for Surface Mounted Permanent Magnet Synchronous Motor Drive in Electric Vehicles

Energies, 2015
The accurate information of the initial rotor position is very critical for successful starting of the Surface-mounted Permanent Magnet Synchronous Motor (SPMSM).
Xuan Wu, Hui Wang, Shoudao Huang, Keyuan Huang, Li Wang   +4 more
doaj   +1 more source

Expanding the frontier of CAR therapy: comparative insights into CAR-T, CAR-NK, CAR-M, and CAR-DC approaches

Annals of Hematology
Chimeric antigen receptor (CAR) therapies have demonstrated remarkable clinical efficacy in hematological malignancies, validating their therapeutic potential. However, challenges such as therapeutic resistance and limited accessibility hinder their broader application.
Zhang, Yiling, Hu, Rong, Xie, Xiaoling, Li, Yuhua   +3 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Deciphering genotype and geography dependent microbiome composition and its role in disease suppression in Ashwagandha

Frontiers in Microbiology
Ashwagandha, Withania somnifera (L.) Dunal is a perennial evergreen shrub widely used to treat mental health disorders and physical debility, and to enhance overall physiological function.
Samadhan Yuvraj Bagul, Shreedevasena S, Parmeshwar Lal Saran, Ganesh Navnath Khadke, Manish Das   +4 more
doaj   +1 more source