Carbacetam Effect on Behavioral Reactions in Experimental Alzheimer’s Disease [PDF]
Introduction. Considering the inadequate results of the actual treatment, the search for new means of pathogenic therapy of Alzheimer’s disease is important. The objective of the study.
Sergiy V Ziablitsev
exaly +5 more sources
Experimental Assessment of Carbacetam Effect on the Cerebral Mitochondria in Rats With Scopolamine-Induced Alzheimer’s Disease [PDF]
Introduction. One of the pathogenic chains in neurodegenerative diseases, and the Alzheimer’s disease especially, is the disorder of cellular energy supply.
Olga G. KMET +5 more
exaly +5 more sources
Dynamics of Endogenous Intoxication Indicators in Condition of Acute Blood Loss Complicated by Ischemia-Reperfusion of the Limb, and Their Correction by Carbacetam [PDF]
Introduction. In the structure of injuries from gunshot wounds dominate the limb injuries that are often complicated by massive bleeding from the main vessels. The only means of rescue on the battlefield is a timely application of a tourniquet.
I. Strelbytska, A. Hudyma
exaly +9 more sources
Violations of Antioxidant-Prooxidant Spleen Index and Ceruloplasmin Content in Serum During Acute Blood Loss, Complicated by Ischemia-Reperfusion of Limb and the Effectiveness of Its Correction With Carbacetam [PDF]
Antioxidant-prooxidant imbalance is one of the key mechanisms of acute blood loss and ischemic-reperfusion syndrome. Under these conditions, the level of ceruloplasmin (CP) plays an important role, enhancing antioxidant protection and promoting ...
I. V. Iavorska
exaly +7 more sources
Oxygen-Dependent Oxidation of Proteins in the Pathogenesis of Spleen Injury Caused by Acute Blood Loss, Complicated by Ischema-Reperfusion of the Limb and the Efficiency of Their Correction by Carbacetam [PDF]
Activation of free radical processes is one of the key mechanisms of acute blood loss and ischemic-reperfusion syndrome. The spleen plays an important role in adaptive-compensatory processes during the blood loss.
I. V. Iavorska
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The Effect of Acute Blood Loss Complicated by Limb Ischemia-Reperfusion on the Induction of the Apoptosis of Pulmonary Leukocytes and Its Correction by Carbacetam [PDF]
The development of acute lung injury is one of the severe complications of massive blood loss. Under these conditions, the apoptosis which is identified as an informative marker of the severity of the pathological process, enhances in the pulmonary ...
O. V. Stakhiv, A. A. Hudyma
exaly +6 more sources
Comparative Analysis of Histological and Morphometric Changes of the Arterial Bed of the Hind Limbs of the Rats in Acute Ischemia-Reperfusion and Correction With Carbacetam [PDF]
Resume. Ischemic-repefusion injury is a complex multifactorial tissue damage as the result of restoration of blood circulation, after the period of ischemia or lack of the oxygen, accompanied by the local and systemic disorders.
T. Veresiuk, P. Selskyy
exaly +7 more sources
Experimental Investigation on Carbacetam Influence on Hypothalamus Tissue in Brain Injury
Relevance. A key role in the pathogenesis of the brain injury is played by destructive changes in the hypothalamus neuroendocrine cells. For the correction of such disorders, promising is carbacetam, which has antihypoxic, anti-edema and anti-shock ...
T I Panova
exaly +7 more sources
Benzodiazepine Receptor Agonist Carbacetam Modulates the Level of Vascular Endothelial Growth Factor in the Retina of Rats With Streptozotocin-Induced Diabetes [PDF]
One of the primary mechanisms of retinal neurodegeneration in diabetes mellitus is gamma-aminobutyric acid (GABA) deficiency that makes the use of GABA-benzodiazepine receptor modulators a promising option for the correction of this diabetic complication.
S. V. Ziablitsev +3 more
exaly +3 more sources
Protein Peroxide Oxidation in the Cerebral Cortex and Hippocampus of Rats With Type 2 Diabetes Mellitus, Under Carbacetam Effect [PDF]
Introduction. One of medical-social chronic consequences of diabetes mellitus is encephalopathy, with an advancing course and development of neurodegenerative disorders in the central nervous system.
Olga G. KMET +4 more
exaly +3 more sources

