Results 21 to 30 of about 126 (60)

Assessment of Carbacetam Effect on the Mitochondria of Hippocampal Neurons in Rats of Different Sexes With Experimental Metabolic Syndrome

Wiadomości Lekarskie
Aim Metabolic syndrome is a complex and multifactorial disorder affecting a large part of the world’s population. Considering the fact that mitochondria plays an important role in energy metabolism and oxidative stress, which is one of the molecular mechanisms damaging different organs and tissues with metabolic
Olha Hnativna Kmet, Olha Mykolaivna Pryzhbylo, Tamara Ivanivna Hrachova, Natalya Mukolaivna Fundiur, Iryna Dmutrivna Vizniuk   +4 more
exaly   +4 more sources

Significance of lipid peroxidation processes in renal excretory dysfunction in cases of acute blood loss complicated by limb ischemia-reperfusion and its correction [PDF]

Journal of Education, Health and Sport, 2019
Introduction. Activation of lipid peroxidation processes, which are exacerbated in cases of limb ischemia-reperfusion associated with temporary application of a tourniquetis a key mechanism of acute blood loss.
V. V. Shatskyi, A. A. Hudyma
doaj   +2 more sources

Changes of Biochemical Indicators of Blood Serum and the Skeletal Muscle Homogenate of the Hind Limbs of the Rats in Acute Ischemia-Reperfusion and in the Condition of Using of the Carbacetam

Reports of Vinnytsia National Medical University, 2020
Annotation. Simulation of ischemia-reperfusion causes the biochemical disorders and changes in the prooxidant-antioxidant system, both in the serum and skeletal muscles of the affected limb. The severity of local and systemic postischemic imbalance decreases in with correction with medicine from the group of nootropics – carabacetam.
A. T. Televiak, P. R. Selskyy, T. O. Veresiuk   +2 more
exaly   +3 more sources

Analysis of the Neurologic Deficit under the Traumatic Brain Injury and Methods of Its Correction [PDF]

Journal of Education, Health and Sport, 2017
Objective of the research. Provide the analysis of the neurologic deficit in dynamics under the experimental traumatic brain injury and methods of its correction by Carbacetam. Materials and the methods of research. The research was held by means of the
S. V. Ziablitsev, O. O. Starodubska, S. L. Bogza   +2 more
doaj   +4 more sources

Changes in the Glutathione System of Rats of Different Ages During Experimental Scopolamine-Induced Neurodegenerate Process: Therapeutic Potential of Carbacetam

Bukovinian Medical Herald
Хвороба Альцгеймера є провідною причиною деменції у світі та характеризується прогресуючим перебігом із формуванням глибоких когнітивних порушень. Одним із ключових патогенетичних механізмів розвитку нейродегенерації є оксидативний стрес. Центральну роль у підтриманні редокс-гомеостазу відіграє глутатіонова система.Мета дослідження – вивчення вікових ...
Y.P. Dreznal, T.I. Kmet
exaly   +4 more sources

Carbacetam attenuates biphasic neuroendocrine dysregulation and improves neurobehavioral recovery after closedhead traumatic brain injury in rats

Wiadomości Lekarskie
Aim: To elucidate neurohormonal mechanisms underlying the development of higher-order behavioral and cognitive disturbances after traumatic brain injury and to substantiate a pathogenetic approach to their correction using carbacetam. Materials and Methods: We examined neuroendocrine dynamics after closedhead TBI in rats and assessed pathogenetically ...
Sergiy V. Ziablitsev, Nadia O. Aleksandrenko, Volodymyr V. Likhodievsky, Danylo I. Yevstifeiev, Mykola S. Babenko, Serhey O. Khudoley, Liudmyla V. Molodan, Yuliia Ya. Fedulenkova, Diana G. Kiriya, Olena P. Sharmazanova, Viktoriia O. Bibichenko   +10 more
openaire   +2 more sources

Dynamics of violations the absorption function of the small intestine in conditions of acute blood loss complicated by ischemia-reperfusion of the limbs and their correction

Journal of Education, Health and Sport, 2021
Introduction. In the structure of modern injuries in wartime and peacetime the share of gunshot wounds increased significantly. The timeliness of applying a tourniquet is one of the main methods of saving lives on the battlefield.
I. Strelbytska, A. Hudyma
doaj   +1 more source

ВПЛИВ ГОСТРОЇ КРОВОВТРАТИ, УСКЛАДНЕНОЇ ІШЕМІЄЮ-РЕПЕРФУЗІЄЮ КІНЦІВКИ, НА ДИНАМІКУ ПОКАЗНИКІВ ГЛУТАТІОНОВОЇ АНТИПЕРОКСИДАЗНОЇ СИСТЕМИ В СЕЛЕЗІНЦІ ТА ЙОГО КОРЕКЦІЯ КАРБАЦЕТАМОМ [PDF]

, 2021
Introduction. Disruption of the glutathione antiperoxidase system is one of the key mechanisms of acute blood loss and ischemic-reperfusion syndrome. The spleen plays an important role in adaptive-compensatory processes in the conditions of blood loss ...
Яворська , І. В., І. В. Яворська   +1 more
core   +1 more source

ВПЛИВ ГОСТРОЇ КРОВОВТРАТИ, УСКЛАДНЕНОЇ ІШЕМІЄЮ-РЕПЕРФУЗІЄЮ КІНЦІВКИ, НА ДИНАМІКУ ПОКАЗНИКІВ ЕНЗИМНОЇ ЛАНКИ АНТИОКСИДАНТНОГО ЗАХИСТУ В СЕЛЕЗІНЦІ ТА ЙОГО КОРЕКЦІЯ КАРБАЦЕТАМОМ [PDF]

, 2021
Violation of the enzymatic link of antioxidant protection belongs to one of the key pathogenic mechanisms of damage to internal organs in conditions of acute blood loss and ischemic-repefusion syndrome.
Яворська, І. В., І. В. Яворська   +1 more
core   +1 more source

ДИНАМІКА АНТИОКСИДАНТНО-ПРООКСИДАНТНОГО БАЛАНСУ ТОНКОЇ КИШКИ ПІД ВПЛИВОМ ГОСТРОЇ КРОВОВТРАТИ, УСКЛАДНЕНОЇ ІШЕМІЄЮ-РЕПЕРФУЗІЄЮ КІНЦІВКИ, ТА ЙОГО КОРЕКЦІЯ КАРБАЦЕТАМОМ [PDF]

, 2021
Introduction. The spread of terrorism and local armed conflicts has led to an increase in the frequency of gunshot injuries with massive external bleeding from the extremities.
Стрельбицька, В. В., Гудима, А. А., А. А. Гудима, В. В. Стрельбицька   +3 more
core   +1 more source