Low Catalyst Loadings in Olefin Metathesis: Synthesis of Nitrogen Heterocycles by Ring-Closing Metathesis [PDF]
, 2010 A series of ruthenium catalysts have been screened under ring-closing metathesis (RCM) conditions to produce five-, six-, and seven-membered carbamate-protected cyclic amines. Many of these catalysts demonstrated excellent RCM activity and yields with as
Champagne, Timothy M. +8 more
core +2 more sources
Crystals, 2019 Crystal structure elucidations of bio-based polymers provide invaluable data regarding structure−property relationships. In this work, we achieved synthesis and Single Crystal X-ray Diffraction (SCXRD) structural determination of a new furan-based ...
Yves L. Dory +5 more
doaj +1 more source
Synthesis of analogues of (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate, an isoprenoid precursor and human γδ T cell activator [PDF]
, 2008 (E)-1-Hydroxy-2-methyl-but-2-enyl 4-diphosphate (HMBPP) is an intermediate in the non-mevalonate pathway for the biosynthesis of isoprenoids and also serves as a very strong activator of human gamma delta T cells expressing V gamma 9V delta 2 receptors ...
Jomaa, Hassan +5 more
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Acta Crystallographica Section E: Crystallographic Communications, 2015 The title carbamate monohydrates, C13H12N2O2·H2O and C12H9BrN2O2·H2O, form isomorphous crystals that are isostructural in their primary hydrogen-bonding modes.
Pavle Mocilac, John F. Gallagher
doaj +1 more source
Synthesis and Biochemical Evaluation of Baicalein Prodrugs
Pharmaceutics, 2021 Baicalein (5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one), a flavonoid analog from Scutellaria baicalensis, possesses several pharmacological activities including antioxidant, antiproliferative, and anti-inflammatory activities.
Sang-Hyun Son +8 more
doaj +1 more source
Lithium and aluminium carbamato derivatives of the utility amide 2, 2, 6, 6- tetramethylpiperidide [PDF]
, 2010 Insertion of CO2 into the metal-N bond of a series of synthetically-important alkali-metal TMP (2,2,6,6-tetramethylpiperidide) complexes has been studied.
Abram +50 more
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Crystal structure of ethyl N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamate
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C14H17N3O3, the dihedral angle between the benzene ring and the five-membered dihydropyrazole ring is 52.26 (9)°. The ethyl ester group is approximately planar (r.m.s.
Muhammad Danish +3 more
doaj +1 more source
Transfer of electrophilic NH using convenient sources of ammonia: direct synthesis of N–H sulfoximines from sulfoxides [PDF]
, 2016 The transfer of nitrogen atoms is extremely valuable in the preparation of medicinal compounds. Here, a new system for NH transfer is developed to prepare sulfoximines, which are emerging as valuable motifs for drug discovery.
Bentley +43 more
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1-[2-(1H-Pyrrole-2-carbonyl)phenyl]-3-(4-methoxyphenyl)urea
Molbank, 2022 For the synthesis of 1-(2-(1H-pyrrole-2-carbonyl)phenyl)-3-(4-methoxyphenyl)urea, the final product, two different methods were used, in one or two steps, from (2-aminophenyl)(1H-pyrrol-2-yl)methanone.
Antonia G. Sarantou, George Varvounis
doaj +1 more source
Tissue compatibility of poly(hydroxypropylglutamate)-prazosin conjugates [PDF]
, 1992 Biocompatibility of an injectable biodegradable drug delivery system for prazosin was investigated in Sprague-Dawley rats by histological studies after subcutaneous injection ofpoly(hydroxypropyl glutamate)-prazosin (PHPG-prazosin) conjugate particles ...
Anderson, James M. +4 more
core +2 more sources