Results 251 to 260 of about 127,195 (275)

Defluoroalkylation of Trifluoromethane with Organolithium Reagents: Mechanism and Synthesis of Fluoroalkenes

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
We report a rare example of the transformation of HCF3 into a fluoroalkene functional group through defluoroalkylation. We rationalise product formation through DFT calculations, scale‐up the synthesis through continuous flow methods, and show that a fluoroalkene reagent derived from HCF3 is a competent nucleophile for the fluoroethenylation of a range
Hodan R. Warsame, Sarah L. Patrick, James A. Bull, Philip W. Miller, Mark R. Crimmin   +4 more
wiley   +2 more sources

Long-Term Risk of Pancreatic Cancer After Acute Acetylcholinesterase Inhibitor Insecticide Exposure: A Nationwide Cohort Study. [PDF]

Curr Oncol
Moon J, Jung E, Chun B, Kim D, Seong Y.
europepmc   +1 more source

Dual cholinergic modulation in dementia: Quinuclidine carbamates targeting butyrylcholinesterase and α7 nicotinic receptor

Peter Mastnak-Sokolov, Damijan Knez, Anton Meden, Nika Strašek Benedik, Svit Ferjančič Benetik, Martina Hrast Rambaher, Maša Zorman, Florian Nachon, Xavier Brazzolotto, Kent Jardemark, Oscar Jungholm, Joseph D. Bruton, Emilia Strandback, T. Nyman, Mohammed Shahid, Stanislav Gobec   +15 more
openalex   +1 more source

Synthesis and use of polyamine derivatives as internal mass spectrometry standards [PDF]

Dar, Sami Ullah
core  

Characterisation of the N‐Methyltransferase SgPsmC: Application in the Kinetic Resolution of Pyrroloindolines

Angewandte Chemie International Edition, Volume 65, Issue 2, 9 January 2026.
The N‐methyltransferase SgPsmC was characterised and applied in the kinetic resolution (KR) of easily obtainable pyrroloindolines. Substitution at 3a‐position proved to be a principal determinant for the enzyme's enantioselectivity. While moving toward laboratory scale, the reaction was coupled with a methionine adenosyl transferase for in situ ...
Benjamin Panagiotis Chapple, Lia Nitz, Pascal Schneider, Birgit Henßen, Sebastian Myllek, Mona Haase, Thomas Classen, Jörg Pietruszka   +7 more
wiley   +1 more source

Direct Access to Acylboranes via Formal Condensation of Carboxylic Acids with Ligated Boranes

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
A nickel‐catalyzed, radical‐based C(acyl)–B cross‐coupling strategy has been developed for the efficient synthesis of bench‐stable, phosphonite‐ligated acylborane compounds from readily available carboxylic acids. This methodology not only provides access to acylboranes with diverse reactivity profiles but also establishes a versatile platform for the ...
Chen‐Yan Cai, Chao Hu, Katherine E. Colbaugh, Rohan R. Merchant, Shuming Chen, Tian Qin   +5 more
wiley   +2 more sources

Design, Synthesis, and Characterization of Novel, Subtype-Selective Fluorescent Antagonists Targeting the Nociceptin/Orphanin FQ Opioid Peptide Receptor. [PDF]

J Med Chem
Farmer GJ, Sanchez J, Millns A, Antony T, Canals M, Lane JR, Mistry SN.   +6 more
europepmc   +1 more source

Discovery of benzyl carbamate inhibitors of coronavirus M^pro enzymes from a legacy collection of cysteine protease inhibitors

Serafim, Mateus Sá Magalhães, Kronenberger, Thales, Francisco, Karol R., de Sousa Reis, Erik Vinicius, de Oliveira, Ellen Gonçalves, Marcelino e Oliveira, Fernanda Kelly, Fortes, Isadora Serraglio, Fernandes, Thaís Helena Maciel, da Silva, Elany Barbosa, Fajtova, Pavla, Skinner, Danielle E., Syed, Rafay O., de Siqueira-Neto, Jair Lage, Poso, Antti, Mota, Bruno Eduardo Fernandes, Coelho-dos-Reis, Jordana Grazziela Alves, Abrahão, Jônatas Santos, Maltarollo, Vinícius Gonçalves, O’Donoghue, Anthony J., Caffrey, Conor R.   +19 more
openalex   +1 more source

Regulierung der Promiskuitiven Katalyse durch Substratinduzierte Transiente Assemblierung

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
Wir berichten über eine neuartige substratinduzierte transiente Koassemblierung zwischen einem kurzen lysinreichen Peptid und Fmoc‐Gly‐OH. Im aktivierten Zustand zeigt die Assemblierung eine promiskuitive katalytische Aktivität durch die Beschleunigung der Hydrolyse und der C═N‐Kondensationsreaktion.
Ayan Chatterjee, Maximilian Schuler, Marius G. Braun, Christopher V. Synatschke, Qi Lu, Jiyao Yu, David Y. W. Ng, Tanja Weil   +7 more
wiley   +1 more source

Rapidly making biodegradable and recyclable paper plastic based on microwave radiation driven dynamic carbamate chemistry. [PDF]

Nat Commun
Yang X, Yu L, Zhang B, Wang Y, Jia X, Lizundia E, Chen C, Dong F, Qi L, Chen L, Gao E, Xu X, Liu H, Chen C.   +13 more
europepmc   +1 more source