Functionalized cyclic organic carbonates and carbamates are frequently used in a number of transition metal-catalyzed decarboxylative reactions for the construction of interesting molecules.
Linhong Zuo+3 more
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Resveratrol-Based Carbamates as Selective Butyrylcholinesterase Inhibitors: Design, Synthesis, Computational Study and Biometal Complexation Capability [PDF]
Considering our previous experience in the design of new cholinesterase inhibitors, especially resveratrol analogs, in this research, the basic stilbene skeleton was used as a structural unit for new carbamates designed as potentially highly selective ...
Maja Sviben+8 more
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Research Progress on the Reaction of Carbon Dioxide with Hydrazones and Their Derivatives [PDF]
CO2, an abundant and renewable C1 source, presents significant potential for applications in organic synthesis. Hydrazones, recognized for their distinctive properties, exhibit high versatility in synthetic chemistry, facilitating numerous chemical ...
Hong-Xia Sun+12 more
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Heterostilbene Carbamates with Selective and Remarkable Butyrylcholinesterase Inhibition: Computational Study and Physico-Chemical Properties [PDF]
This manuscript reports the synthesis and characterization of 19 novel heterostilbene carbamates, designed as selective butyrylcholinesterase (BChE) inhibitors with potential applications in the treatment of neurodegenerative disorders, particularly ...
Anamarija Raspudić+11 more
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Classification, Chemical, and Toxicological Properties of Carbamate Nerve Agents [PDF]
Nerve agents are usually identified as exceedingly toxic organophosphate compounds like VX and sarin. Nevertheless, although carbamate nerve agents (CNAs) have been developed they constitute the least studied class of nerve agents outside military ...
Georgios Pampalakis
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Norcyanine-Carbamates Are Versatile Near-Infrared Fluorogenic Probes.
Fluorogenic probes in the near-infrared (NIR) region have the potential to provide stimuli-dependent information in living organisms. Here, we describe a new class of fluorogenic probes based on the heptamethine cyanine scaffold, the most broadly used ...
S. Usama+3 more
semanticscholar +1 more source
The ups and downs of alkyl‐carbamates in epilepsy therapy: How does cenobamate differ?
Since 1955, several alkyl‐carbamates have been developed for the treatment of anxiety and epilepsy, including meprobamate, flupirtine, felbamate, retigabine, carisbamate, and cenobamate.
W. Löscher, G. Sills, H. White
semanticscholar +1 more source
Crystal structure of 2-oxo-1,2-diphenylethyl diisopropylcarbamate
The title compound, C21H25NO3, crystallized as a racemic twin in the Sohnke space group P21. In the molecular structure of the title compound, both enantiomers show a highly similar conformation with the urethane function and the benzoyl group showing an
Viktor Martens+2 more
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To reduce anthropogenic carbon dioxide (CO 2 ) emissions, it is desirable to develop reactions that can efficiently convert low concentrations of CO 2 , present in exhaust gases and ambient air, into industrially important chemicals, without involving ...
Hiroki Koizumi+8 more
semanticscholar +1 more source
Potential revival of cholinesterase inhibitors as drugs in veterinary medicine
The cholinergic system is involved in the regulation of all organ systems and has acetylcholine (ACh) as almost its only neurotransmitter. Any substance is called cholinergic if it can alter the action of acetylcholine. Cholinesterases (ChEs) are enzymes
Neža Žnidaršič+3 more
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