Results 21 to 30 of about 74,560 (387)

QSTR Modeling to Find Relevant DFT Descriptors Related to the Toxicity of Carbamates

open access: yesMolecules, 2022
Compounds containing carbamate moieties and their derivatives can generate serious public health threats and environmental problems due their high potential toxicity.
Emma H. Acosta-Jiménez   +8 more
doaj   +1 more source

Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases

open access: yesMolecules, 2021
Neurological and neurodegenerative diseases are debilitating conditions, and frequently lack an effective treatment. Monoacylglycerol lipase (MAGL) is a key enzyme involved in the metabolism of 2-AG (2-arachidonoylglycerol), a neuroprotective ...
Anca Zanfirescu   +4 more
doaj   +1 more source

A Simple and Effective Synthesis of 3- and 4-((Phenylcarbamoyl)oxy)benzoic Acids

open access: yesActa Chimica Slovenica, 2020
Phenserine, posiphen, tolserine and cymserine and its derivatives are experimental Alzheimer’s disease drugs that contain a phenyl phenylcarbamate moiety that is responsible for their anti-Alzheimer activities.
Urban Košak, Stanislav Gobec
doaj   +1 more source

Transition Metal-Free Synthesis of Carbamates Using CO2 as the Carbon Source.

open access: yesChemSusChem, 2020
Utilization of carbon dioxide as a C1 synthon is highly attractive for the synthesis of valuable chemicals. However, activation of CO2 is highly challenging, owing to its thermodynamic stability and kinetic inertness.
Waldemar Schilling, Shoubhik Das
semanticscholar   +1 more source

Crystal structure of 2-oxo-1,2-diphenylethyl diisopropylcarbamate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2021
The title compound, C21H25NO3, crystallized as a racemic twin in the Sohnke space group P21. In the molecular structure of the title compound, both enantiomers show a highly similar conformation with the urethane function and the benzoyl group showing an
Viktor Martens   +2 more
doaj   +1 more source

Synthesis of Amide Enol Carbamates and Carbonates through Cu(OTf)2-Catalyzed Reaction of Ynamides with t-Butyl Carbamates/Carbonates.

open access: yesJournal of Organic Chemistry, 2020
A highly regioselective approach to access amide enol carbamates and carbonates 5a-5c', 7a-7h and 9 was developed through Cu(OTf)2 catalyzed reactions of ynamides 4 with t-butyl carbamates 2, 8 and t-butyl carbonates 6.
Pan Han   +5 more
semanticscholar   +1 more source

Menthol Increases Bendiocarb Efficacy Through Activation of Octopamine Receptors and Protein Kinase A

open access: yesMolecules, 2019
Great effort is put into seeking a new and effective strategies to control insect pests. One of them is to combine natural products with chemical insecticides to increase their effectiveness.
Milena Jankowska   +4 more
doaj   +1 more source

Dithiocarbamates: Properties, Methodological Approaches and Challenges to Their Control

open access: yesToxics, 2023
Dithiocarbamates (DTCs) are a group of chemicals used primarily as fungicides, although they are exploited for various other applications. DTCs represent one of the oldest classes of broad-spectrum fungicides employed worldwide to control fungal diseases
Claudia Campanale   +4 more
doaj   +1 more source

The Experimental Oxime K027—A Promising Protector From Organophosphate Pesticide Poisoning. A Review Comparing K027, K048, Pralidoxime, and Obidoxime

open access: yesFrontiers in Neuroscience, 2019
Poisoning with organophosphorus compounds (OPCs) is a major problem worldwide. Standard therapy with atropine and established oxime-type enzyme reactivators (pralidoxime, obidoxime) is unsatisfactory.
Dietrich E. Lorke   +2 more
doaj   +1 more source

Potential revival of cholinesterase inhibitors as drugs in veterinary medicine

open access: yesFrontiers in Veterinary Science, 2023
The cholinergic system is involved in the regulation of all organ systems and has acetylcholine (ACh) as almost its only neurotransmitter. Any substance is called cholinergic if it can alter the action of acetylcholine. Cholinesterases (ChEs) are enzymes
Neža Žnidaršič   +3 more
doaj   +1 more source

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