Results 21 to 30 of about 74,560 (387)
QSTR Modeling to Find Relevant DFT Descriptors Related to the Toxicity of Carbamates
Compounds containing carbamate moieties and their derivatives can generate serious public health threats and environmental problems due their high potential toxicity.
Emma H. Acosta-Jiménez+8 more
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Neurological and neurodegenerative diseases are debilitating conditions, and frequently lack an effective treatment. Monoacylglycerol lipase (MAGL) is a key enzyme involved in the metabolism of 2-AG (2-arachidonoylglycerol), a neuroprotective ...
Anca Zanfirescu+4 more
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A Simple and Effective Synthesis of 3- and 4-((Phenylcarbamoyl)oxy)benzoic Acids
Phenserine, posiphen, tolserine and cymserine and its derivatives are experimental Alzheimer’s disease drugs that contain a phenyl phenylcarbamate moiety that is responsible for their anti-Alzheimer activities.
Urban Košak, Stanislav Gobec
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Transition Metal-Free Synthesis of Carbamates Using CO2 as the Carbon Source.
Utilization of carbon dioxide as a C1 synthon is highly attractive for the synthesis of valuable chemicals. However, activation of CO2 is highly challenging, owing to its thermodynamic stability and kinetic inertness.
Waldemar Schilling, Shoubhik Das
semanticscholar +1 more source
Crystal structure of 2-oxo-1,2-diphenylethyl diisopropylcarbamate
The title compound, C21H25NO3, crystallized as a racemic twin in the Sohnke space group P21. In the molecular structure of the title compound, both enantiomers show a highly similar conformation with the urethane function and the benzoyl group showing an
Viktor Martens+2 more
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A highly regioselective approach to access amide enol carbamates and carbonates 5a-5c', 7a-7h and 9 was developed through Cu(OTf)2 catalyzed reactions of ynamides 4 with t-butyl carbamates 2, 8 and t-butyl carbonates 6.
Pan Han+5 more
semanticscholar +1 more source
Great effort is put into seeking a new and effective strategies to control insect pests. One of them is to combine natural products with chemical insecticides to increase their effectiveness.
Milena Jankowska+4 more
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Dithiocarbamates: Properties, Methodological Approaches and Challenges to Their Control
Dithiocarbamates (DTCs) are a group of chemicals used primarily as fungicides, although they are exploited for various other applications. DTCs represent one of the oldest classes of broad-spectrum fungicides employed worldwide to control fungal diseases
Claudia Campanale+4 more
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Poisoning with organophosphorus compounds (OPCs) is a major problem worldwide. Standard therapy with atropine and established oxime-type enzyme reactivators (pralidoxime, obidoxime) is unsatisfactory.
Dietrich E. Lorke+2 more
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Potential revival of cholinesterase inhibitors as drugs in veterinary medicine
The cholinergic system is involved in the regulation of all organ systems and has acetylcholine (ACh) as almost its only neurotransmitter. Any substance is called cholinergic if it can alter the action of acetylcholine. Cholinesterases (ChEs) are enzymes
Neža Žnidaršič+3 more
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