Results 51 to 60 of about 810 (205)
Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis
Angewandte Chemie, EarlyView.The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood +6 more
wiley +2 more sources
Angewandte Chemie, EarlyView.A heterogeneous photocatalytic system has been developed that enables the dehydrogenative decarbonylation of primary alcohols under visible light using highly dispersed oxidic iron sites supported on aryl‐modified graphitic carbon nitride (Fe@f–gC3N4).
Jun Hu +11 more
wiley +2 more sources
Molecules, 2019 Functionalized cyclic organic carbonates and carbamates are frequently used in a number of transition metal-catalyzed decarboxylative reactions for the construction of interesting molecules.
Linhong Zuo +3 more
doaj +1 more source
Frontiers in Neuroscience, 2019 Poisoning with organophosphorus compounds (OPCs) is a major problem worldwide. Standard therapy with atropine and established oxime-type enzyme reactivators (pralidoxime, obidoxime) is unsatisfactory.
Dietrich E. Lorke +2 more
doaj +1 more source
Nitro Reduction‐Based RNA Control and Ultrafast Release
Angewandte Chemie, EarlyView.A chemical RNA caging–uncaging strategy based on nitro reduction is described. Nitroaryl groups introduced via acylation temporarily block the functions of diverse RNAs in vitro and in living cells. Treatment with a diboronic acid–bipyridine mixture rapidly reduces the nitro groups, releasing RNAs and restoring their activity.
Yiran Zhao +6 more
wiley +2 more sources
Toxicity of Certain Chemical Compounds Against Aphids, Leafhoppers AND Related Predators on Faba Bean Fields [PDF]
Journal of Plant Protection and PathologyFaba bean, Vicia faba L., is a main nutritive source for human beings and their domestic animals. Many insect pests have been recorded on Vicia faba such as aphids, leafhoppers which are the most harmful insects, causing a considerable loss in yield ...
Hanaa Harby +3 more
doaj +1 more source
Arhiv za Higijenu Rada i ToksikologijuInsecticides are pervasive in modern world, with humans being exposed through multiple pathways including dietary intake, occupational exposure, farming activities, residential proximity to crops, and household use.
Tomac Patricia +3 more
doaj +1 more source
Sensors, 2008 The conventional analysis of pesticide residues in analytical commodities, such as tobacco and tobacco products is a labor intensive procedure, since it is necessary to cover a wide range of different chemicals, using a single procedure.
Spiridon Kintzios +5 more
doaj
Carbamates as Potential Prodrugs and a New Warhead for HDAC Inhibition
Molecules, 2018 We designed and synthesized carbamates of the clinically-approved HDAC (histone deacetylase) inhibitor vorinostat (suberoylanilide hydroxamic acid, SAHA) in order to validate our previously-proposed hypothesis that these carbamates might serve as ...
Kristina King +4 more
doaj +1 more source
Research Progress on the Reaction of Carbon Dioxide with Hydrazones and Their Derivatives
MoleculesCO2, an abundant and renewable C1 source, presents significant potential for applications in organic synthesis. Hydrazones, recognized for their distinctive properties, exhibit high versatility in synthetic chemistry, facilitating numerous chemical ...
Hong-Xia Sun +12 more
doaj +1 more source