Results 91 to 100 of about 61,637 (294)

Method of simultaneous determination of carbamazepine and carbamazepine-10,11-epoxide by HPLC-MS/MS

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
Carbamazepine is the drug of first choice in the treatment of trigeminal neuralgia, epilepsy and other neurological diseases. Carbamazepine is known to have a narrow therapeutic range, and hereby the auto-induction of its metabolism with prolonged use ...
T. A. Rodina   +7 more
doaj  

Co‐occurrence of childhood absence epilepsy and self‐limited focal epilepsy interictal discharges: Differences from childhood absence epilepsy alone

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Some children with Childhood Absence Epilepsy (CAE) exhibit focal abnormalities similar to those observed in Self‐Limited Focal Epilepsies of Childhood (SeLFEs). It remains unclear whether this subgroup of patients may present distinct clinical characteristics or prognoses compared to those with CAE and generalized discharges alone ...
Giulia Barbagallo   +6 more
wiley   +1 more source

Development of ternary solid dispersions with hydrophilic polymer and surface adsorbent for improving dissolution rate of carbamazepine

open access: yesSaudi Pharmaceutical Journal, 2018
In this study solid dispersions of carbamazepine in the hydrophilic Kollidon® VA64 polymer, adsorbed onto Neusilin® UFL2 adsorption carrier have been employed to improve carbamazepine dissolution rate.
Tanja Vojinović   +6 more
doaj  

Carbamazepine for chronic neuropathic pain and fibromyalgia in adults.

open access: yesCochrane Database of Systematic Reviews, 2014
BACKGROUND This is an update of a Cochrane review entitled 'Carbamazepine for acute and chronic pain in adults' published in Issue 1, 2011. Some antiepileptic medicines have a place in the treatment of neuropathic pain (pain due to nerve damage).
P. Wiffen   +3 more
semanticscholar   +1 more source

Antiseizure medication choice in diffuse glioma: A single‐center population‐based experience

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Several antiseizure medications (ASMs) can be considered as first‐line treatment for glioma‐associated epilepsy (GAE). We aimed to find out, if there are subgroups of glioma patients which may benefit from different first‐line ASMs. Methods All diffuse glioma (grade 2–4) patients, who were in contact with Helsinki University Hospital
Leena Ollila, Reina Roivainen
wiley   +1 more source

Protective Effect of Wheat Germ Oil on Sex Hormones Disorders and Uterine Tissue Disorders Morphology Following Treatment with Carbamazepine in Epileptic Female Mice with Pentylenetetrazol [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2015
Background & Objective: Epilepsy is one of the common neurological diseases and carbamazepine is an antiepileptic drug that causes oxidative stress, endocrine and the reproductive system long term disorders.
Elham Ahmadi   +3 more
doaj  

Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.

open access: yesNew England Journal of Medicine, 2011
BACKGROUND Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main cause of the Stevens-Johnson syndrome (SJS) and its related disease, toxic epidermal necrolysis (TEN), in Southeast Asian countries.
Pei Chen   +32 more
semanticscholar   +1 more source

Real‐world effectiveness and tolerability of cenobamate in drug‐resistant epilepsy: A retrospective analysis of the patients included into the Early Access Programs (EAP) in Germany, France, and United Kingdom

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Investigate real‐world outcomes in drug‐resistant epilepsy (DRE) patients treated with cenobamate as adjunctive treatment to other antiseizure medications (ASMs) within the Early Access Programs (EAP) in Germany, France, and the United Kingdom.
Sylvain Rheims   +13 more
wiley   +1 more source

Epilepsy control with carbamazepine monotherapy from a genetic perspective

open access: yesBMC Pharmacology and Toxicology, 2018
Background Ethnicity variation is one of the main factors that may affect drug response in clinical practice. As MTHFR gene affects different transcriptome and proteome which affect the clinical response of drugs.
Shakir Ullah   +5 more
doaj   +1 more source

Infrequent Monitoring of the Effects of Valproate and Carbamazepine Therapy in Patients With Epilepsy in Nigeria

open access: yesJournal of Central Nervous System Disease, 2020
Background: Carbamazepine and valproate are widely used in the treatment of epileptic seizures. However, these agents exhibit certain adverse effects including hematopoietic disorders (carbamazepine) and severe hepatotoxicity (valproate).
Unyime Israel Eshiet   +2 more
doaj   +1 more source

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