Results 101 to 110 of about 38,738 (216)

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Natural language processing‐based emotion and usage analysis of an AI‐powered chatbot for epilepsy support

Epilepsia Open, EarlyView.
Abstract Objective Artificial intelligence (AI)‐powered chatbots are increasingly used for patient education and mental health support, yet their effectiveness in epilepsy care remains underexplored. This study examines text‐based interactions between users and EpiloBot, an epilepsy‐focused chatbot, to understand conversational patterns and emotional ...
Keiichi Watanuki, Ryoya Oba, Naoki Nozawa, Tomoki Ishihara, Koko Oga, Takayuki Iwayama, Takafumi Shiganami, Sayaka Kobayashi, Hironori Kuga, Haruo Yoshimasu, Izumi Kuramochi   +10 more
wiley   +1 more source

NEW METHODS OF OPTIMIZATION OF EPILEPSY PHARMACOTHERAPY: USE OF BAYESIAN PHARMACOKINETIC MODELING

Эпилепсия и пароксизмальные состояния, 2016
There was carried out the therapeutic drug monitoring of antiepileptic drug carbamazepine by use of a bayesian mathematical modeling method in 47 patients with a focal epilepsy.
Z. А. Suslina, А. K. Sariev, D. А. Аbaimov, T. YU. Noskova, R. D. Sejfulla, V. V. Shvedkov, D. I. Prokhorov, M. V. Shiryaeva, L. А. Mota   +8 more
doaj  

Expanding the electroclinical spectrum of TANC2‐related disorders: Lennox–Gastaut syndrome and related developmental epileptic phenotypes

Epilepsia Open, EarlyView.
Abstract Objective Neurodevelopmental disorders (NDDs) and epilepsy are often associated. Increasing evidence highlights a pivotal role for pathogenic variants in genes encoding synaptic scaffolding proteins. Within this group, TANC2 has recently been implicated in intellectual developmental disorder with autistic features and language delay, with or ...
Lorenzo Perilli, Carlotta Stipa, Gianmichele Villano, Laura Licchetta, Leo Strothmann, Robin Tobias Jauss, Gerhard Josef Kluger, Raffaella Minardi, NETRE consortium, Giuseppe Gobbi, Salvatore Grosso, Francesca Bisulli, Pasquale Striano   +12 more
wiley   +1 more source

Response to anti‐seizure medications in children carrying novel or previously reported HCN1 gene variants

Epilepsia Open, EarlyView.
Abstract Objective Variants in the HCN1 gene cause a syndrome of childhood epilepsy and developmental disability with a broad phenotypic range. Many affected children manifest with early infantile epileptic encephalopathy (EIEE) and highly drug‐resistant epilepsy.
Marium N. Khan, Nicholas P. Poolos
wiley   +1 more source

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch, Jakob Johann Schmidt, Daniel Delev, Roland Coras, Ingmar Blümcke, Ruth Beckervordersandforth   +5 more
wiley   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Removal of pharmaceuticals from municipal wastewater using a powdered activated carbon‐supplemented moving bed membrane bioreactor

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The new European Union Wastewater Directive 2024/3019 requires upgrading sewage treatment plants to achieve 80% removal of micropollutants. This study aimed to compare different Powdered Activated Carbon dosing strategies within a hybrid Moving Bed‐Membrane Bioreactor (PAC‐MB‐MBR) system, to evaluate its performance and to study the
Athanasia Iliopoulou, Petros Mastoras, Georgia Gatidou, Kallisti Skarveli, Konstantina Adamaki, Olga S Arvaniti, Maria Aloupi, Michail S Fountoulakis, Athanasios S Stasinakis   +8 more
wiley   +1 more source

A real‐world analysis of AI chatbot performance for medicines information enquiries

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background The provision of medicines information (MI) services requires interpretation and clinical judgement of complex scenarios by pharmacists. To date, few studies have assessed the performance of artificial intelligence (AI) chatbots to assist pharmacists providing MI advice.
Duncan Yorkston, Tracey Borrie, Paul Chin   +2 more
wiley   +1 more source

MODERN VIEW ON CARBAMAZEPINE PROLONGED DOSAGE FORMS USAGE IN PATIENTS WITH EPILEPSY (LITERATURE REVIEW)

Эпилепсия и пароксизмальные состояния, 2016
Data on carbamazepine prolonged dosage forms use for treatment of epilepsy are presented in current review. Expediency of carbamazepine prolonged forms use in patients with different epilepsy forms and types of seizures is demonstrated.
G. N. Avakyan, S. G. Burd
doaj