Synthesis and application of hypercrosslinked polymers with weak cation-exchange character for the selective extraction of basic pharmaceuticals from complex environmental water samples [PDF]
, 2010 The synthesis of high specific surface area sorbents (HXLPP-WCX) in the form of hypercrosslinked polymer microspheres with narrow particle size distributions, average particle diameters around 6 µm, and weak cation exchange (WCX) character, is described.
Borrull, F. +5 more
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British Journal of Clinical Pharmacology, EarlyView.Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
Protective Effect of Wheat Germ Oil on Sex Hormones Disorders and Uterine Tissue Disorders Morphology Following Treatment with Carbamazepine in Epileptic Female Mice with Pentylenetetrazol [PDF]
Journal of Advanced Biomedical Sciences, 2015 Background & Objective: Epilepsy is one of the common neurological diseases and carbamazepine is an antiepileptic drug that causes oxidative stress, endocrine and the reproductive system long term disorders.
Elham Ahmadi +3 more
doaj
The influence of CYP2C8*3 on carbamazepine serum concentration in epileptic pediatric patients
Balkan Journal of Medical Genetics, 2016 The aim of the present study was to investigate the distribution of CYP2C8 variants *3 and *5, as well as their effect on carbamazepine pharmacokinetic properties, in 40 epileptic pediatric patients on carbamazepine treatment.
Milovanovic DD +7 more
doaj +1 more source
Outpatient alcohol detoxification: Implementation efficacy and outcome effectiveness of a model project [PDF]
, 2004 Background: The aim of the study was to examine the practicability and implementation efficacy of an alcohol outpatient detoxification model and the concomitant `motivational' psychotherapeutic approach.
Horak, M., Soyka, Michael
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British Journal of Clinical Pharmacology, EarlyView.Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway +24 more
wiley +1 more source
Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine
BMEMat, EarlyView.Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo +9 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Can hydrophobic, shape‐selective zeolites efficiently remove the persistent pharmaceutical CBZ from water? This work moves beyond the static picture of interaction energies by modeling diffusion with umbrella sampling and machine‐learned potentials. Even high intrinsic diffusion barriers can be overcome through exergonic adsorption from water, yielding
Jakob Brauer +4 more
wiley +1 more source
Method of simultaneous determination of carbamazepine and carbamazepine-10,11-epoxide by HPLC-MS/MS
Регуляторные исследования и экспертиза лекарственных средств, 2018 Carbamazepine is the drug of first choice in the treatment of trigeminal neuralgia, epilepsy and other neurological diseases. Carbamazepine is known to have a narrow therapeutic range, and hereby the auto-induction of its metabolism with prolonged use ...
T. A. Rodina +7 more
doaj
The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database. [PDF]
, 2013 AIMS: To investigate whether the use of carbamazepine is associated with reduced risk of Parkinson's disease. METHODS: We conducted a population-based, matched case-control study of patients randomly selected from the UK General Research Practice ...
Douglas, Ian, Skow, Aine, Smeeth, Liam
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