Results 101 to 110 of about 61,637 (294)
Noninvasive brain stimulation as focal epilepsy treatment in the hospital, clinic, and home
Epilepsia Open, EarlyView.Abstract Objective Noninvasive brain stimulation (NIBS) provides a treatment option for patients not eligible for surgical intervention or who seek low‐risk approaches and may be used in the hospital, clinic, and at home. Our objective is to summarize our single‐center experience with multiple NIBS approaches for the treatment of focal epilepsy ...
Karimul Islam +7 more
wiley +1 more source
A pro-convulsive carbamazepine metabolite: Quinolinic acid in drug resistant epileptic human brain
Neurobiology of Disease, 2012 Drugs and their metabolites often produce undesirable effects. These may be due to a number of mechanisms, including biotransformation by P450 enzymes which are not exclusively expressed by hepatocytes but also by endothelial cells in brain from ...
Chaitali Ghosh +7 more
doaj
Clinical toxicology, 2014 Context. The Extracorporeal Treatments in Poisoning (EXTRIP) workgroup was created to provide evidence and consensus-based recommendations on the use of extracorporeal treatments (ECTRs) in poisoning. Objectives.
M. Ghannoum +9 more
semanticscholar +1 more source
Effects of perampanel on bone health in adult patients with epilepsy
Epilepsia Open, EarlyView.Abstract Objective The objective was to assess the effects of perampanel (PER) on bone metabolism and bone mineral density (BMD) in adult patients with epilepsy. Methods This retrospective study included consecutive patients admitted to the Epilepsy Center of Sichuan Provincial People's Hospital from January 2023 to June 2024.
Mingxing Yu +8 more
wiley +1 more source
Journal of Interdisciplinary Medicine, 2017 An uncomplicated, sensitive liquid chromatography linked to mass spectrometry (LC/MS) for evaluation of carbamazepine and carbamazepine-10,11-epoxide (its metabolite) in human plasma, human saliva, rat plasma, and rabbit plasma was developed.
Andonie Dan +4 more
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2017 Objective: To investigate the protective effect of purslane with carbamazepine treatment. Methods: Male albino rats were modulated by pilocarpine to be epileptic.
Widad Makhdour Al-Bishri +2 more
doaj +1 more source
JAMA dermatology, 2013 IMPORTANCE The US Food and Drug Administration recommends screening for the HLA-B*1502 allele before initiation of carbamazepine therapy in patients of Asian ancestry, but there remains unclear evidence of a relationship between HLA-B*1502 and Stevens ...
Wimonchat Tangamornsuksan +4 more
semanticscholar +1 more source
Epilepsia Open, EarlyView.Abstract Objective The AMPA study (Study 501; NCT04257604) was a multicenter, prospective, 12‐month observational study in Italy that evaluated the effectiveness and safety of adjunctive perampanel in patients with focal‐onset seizures (FOS), with or without focal to bilateral tonic–clonic seizures (FBTCS).
Alfredo D'Aniello +24 more
wiley +1 more source
A quick review of carbamazepine pharmacokinetics in epilepsy from 1953 to 2012
Journal of Research in Medical Sciences, 2013 Background: Carbamazepine has been used as AEDs since 1965, and is most effective against partial seizures. Two basic mechanisms of action have been proposed: 1) enhancement of sodium channel inactivation by reducing high-frequency repetitive firing of ...
Zahra Tolou-Ghamari +3 more
doaj
Therapeutic drug monitoring and methods of quantitation for carbamazepine
Journal of Mind and Medical Sciences, 2017 Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Cristian Tuchila +6 more
doaj +1 more source