How Can We Move Clinical Genomics Beyond the Hype? [PDF]
, 2011 Examines the debate over increased use of genetic testing, due in part to lax regulation, and its consequences: wasteful spending, patient harm, and health system challenges.
Michael L. Millenson
core
Molecular imprinting for neurology: Materials, applications, and limitations
Ibrain, EarlyView.Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma +3 more
wiley +1 more source
Uptake, Partitioning, and Accumulation of High and Low Rates of Carbamazepine in Hydroponically Grown Lettuce (Lactuca sativa var. capitata) [PDF]
Emily R. Stamm +3 more
openalex +1 more source
Permeability of 16 Straight‐ and Branched‐Chain Parabens Using the Caco‐2 Assay
Journal of Applied Toxicology, EarlyView.ABSTRACT The in vitro intestinal permeability of straight‐ and branched‐chain parabens has not been extensively investigated. Sixteen parabens were tested in the Caco‐2 assay. Passive diffusion was measured using PAMPA. The transport of the MCT1 substrate, p‐coumaric acid, as well as propylparaben and isopropylparaben, was investigated.
Nicola J. Hewitt +3 more
wiley +1 more source
NEW METHODS OF OPTIMIZATION OF EPILEPSY PHARMACOTHERAPY: USE OF BAYESIAN PHARMACOKINETIC MODELING
Эпилепсия и пароксизмальные состояния, 2016 There was carried out the therapeutic drug monitoring of antiepileptic drug carbamazepine by use of a bayesian mathematical modeling method in 47 patients with a focal epilepsy.
Z. А. Suslina +8 more
doaj
Carbamazepine Adsorption onto Giant Macroporous Silica and Adaptive Neuro-Fuzzy Inference System Modeling [PDF]
Alper Alver +5 more
openalex +1 more source
Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial [PDF]
, 2007 Objective: To compare the behavioural side effects associated with two commonly used antiepilepsy drugs--phenobarbital and carbamazepine--in children in Bangladesh. Design: Prospective randomised controlled single centre trial.
Banu, S.H. +5 more
core
In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters
The Journal of Clinical Pharmacology, EarlyView.Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou +9 more
wiley +1 more source
Carbamazepine and GABA have distinct effects on seizure onset dynamics in mouse brain slices [PDF]
, 2020 Dakota Crisp +4 more
openalex +1 more source