Results 201 to 210 of about 82,006 (284)

Dental drugs with proarrhythmic risk in patients with Brugada syndrome: precaution instructions for practices in the field of orofacial pain. [PDF]

Front Cardiovasc Med
Han D, Cho NY, Cho ES, Roh SY.
europepmc   +1 more source

Spatial Variability in Trace Organic Compound Reactivity During Urban River Infiltration Into an Alluvial Aquifer

Water Resources Research, Volume 62, Issue 5, May 2026.
Abstract Trace organic compounds (TrOCs) in lotic systems pose risks for ecosystem and human health. TrOCs can enter groundwater along losing river sections, yet little is known about the spatial extent of infiltration zones and the biogeochemical factors controlling the spatial variability of TrOC reactivity and removal, particularly along river‐to ...
Jonas L. Schaper, Olaf A. Cirpka, Malte Posselt, Joerg Lewandowski, Karin Meinikmann, Anke Putschew, Christiane Zarfl   +6 more
wiley   +1 more source

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

British Journal of Pharmacology, Volume 183, Issue 10, Page 2324-2340, May 2026.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann, Mariana O. Popa, Karen T. Elvers, Misa Oyama, Daniel Ulrich, Marcus Hanley, Gui Jie Feng, Thomas Hathaway, William T. Ralvenius, Thomas Grampp, Dietmar Benke, John R. Atack, Hanns Ulrich Zeilhofer   +12 more
wiley   +1 more source

Evaluation of Cardiac Structural Changes Induced by Carbamazepine-Based Nanotherapeutics in an Experimental Epilepsy Model. [PDF]

Nanomaterials (Basel)
Tokpınar A, İlhan H, Tan S, Kazancı S, Harman Civek CZ, Tokpınar RK, Kaymak E, Değermenci M, Baş O.   +8 more
europepmc   +1 more source

The Effect of the Anticonvulsant Topiramate on Acetylcholine‐Induced Calcium Signals is Linked to Sirt‐1 Activity

European Journal of Neuroscience, Volume 63, Issue 9, May 2026.
This work provides a potential new link between the anticonvulsive Topiramate, the deacetylase Sirt‐1 and the cholinergic signalling, suggesting that Topiramate may modulate cholinergic pathways in a Sirt‐1 depended manner. ABSTRACT Although some forms of epilepsy directly result from mutations in nicotinic acetylcholine receptors, none of the ...
Marie‐Luise Kümmel
wiley   +1 more source

Effectiveness of laser photobiomodulation in the management of trigeminal neuralgia: a systematic review and meta-analysis. [PDF]

Lasers Med Sci
Taddeucci PDC, Louzeiro GC, Cherubini K, Spanemberg JC, Salum FG.   +4 more
europepmc   +1 more source

Interrelationships between serum 25-hydroxycalciferol and bone mass in adults on long term antiepileptic drug therapy [PDF]

, 1983
Berlit, Peter, Janz, D., Krause, Klaus-Henning, Meinardi, H., Oxley, J., Schmidt-Gayk, Heinrich   +5 more
core  

Evaluation of drug causality in SJS/TEN: The role of the lymphocyte transformation test and conventional/modified IFN-γ ELISpot assays. [PDF]

World Allergy Organ J
Soliman MH, Mohamed Saber NI, Ouda IM, Mohamed MF, Elkholy B, Haleem Shousha GA, Elbialy AA, El-Korashi LA.   +7 more
europepmc   +1 more source

Clinical Evaluation of Drug-Drug Interactions With Aficamten. [PDF]

Clin Transl Sci
Maharao N, Xu D, Divanji P, Simkins TJ, Li J, Dumitrescu C, Solanki P, Griffith A, Heitner SB, Kupfer S, German P, Lutz JD.   +11 more
europepmc   +1 more source