Results 211 to 220 of about 61,637 (294)

The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial

open access: yesThe Lancet, 2007
A. Marson   +28 more
semanticscholar   +1 more source

A Comprehensive CYP2D6 Drug–Drug–Gene Interaction Network for Application in Precision Dosing and Drug Development

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1718-1731, June 2025.
Conducting clinical studies on drug–drug‐gene interactions (DDGIs) and extrapolating the findings into clinical dose recommendations is challenging due to the high complexity of these interactions. Here, physiologically‐based pharmacokinetic (PBPK) modeling networks present a new avenue for exploring such complex scenarios, potentially informing ...
Simeon Rüdesheim   +14 more
wiley   +1 more source

Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1811-1819, June 2025.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund   +5 more
wiley   +1 more source

Sorption of Sulfonamide Antibiotics in Peat Soils With Different Properties

open access: yesJournal of Plant Nutrition and Soil Science, Volume 188, Issue 3, Page 482-494, June 2025.
Sulfonamide antibiotics contaminate peat soils where they are sorbed to functional groups in a pH‐dependent manner that can be successfully described by QSAR. ABSTRACT Background Sulfonamide antibiotics have been discovered as emerging pharmaceutical pollutants worldwide and are only poorly removed in wastewater treatment.
Eric Mirenga, Sören Thiele‐Bruhn
wiley   +1 more source

Non‐Thermal Plasma Oxidation Processes for the Removal of Pharmaceuticals in Water: Diclofenac and Diclofenac/Carbamazepine Mixture

open access: yesPlasma Processes and Polymers, Volume 22, Issue 6, June 2025.
The results of the biological tests of the treated solutions by NTP were systematically compared to the initial solutions without plasma treatment (w/o plasma) ones. The variations of viability of the cells for DCF + CBZ mix could be explained by the concentrations of the produced species during the plasma treatment.
Manoj P. Rayaroth   +7 more
wiley   +1 more source

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