Results 231 to 240 of about 47,769 (294)

Treatment of epilepsy using newer antiseizure medications: A retrospective cohort study of prescription patterns in Sweden 2013–2022

Epilepsia, EarlyView.
Abstract Objective This study aimed to analyze the choice of newly introduced antiseizure medications (ASMs; brivaracetam, cannabidiol, cenobamate, fenfluramine, and perampanel) by age and sex, and the use of these ASMs in relation to regulatory approval.
Kristian Bolin, Patric Berling, Torbjörn Tomson   +2 more
wiley   +1 more source

Left atrial remodeling in epilepsy: A comparative echocardiographic study of left atrial emptying fraction and left atrial volumetric index in patients with epilepsy

Epilepsia, EarlyView.
Abstract Objective Patients with epilepsy (PWE) are at increased risk for cardiac abnormalities, including arrhythmias, structural changes, and sudden unexpected death in epilepsy (SUDEP). Although previous studies have examined ventricular dysfunction, left atrial (LA) structural and mechanical changes remain underexplored.
Selcen Duran, Yalcin Boduroglu
wiley   +1 more source

Performance of Copper as a Catalyst for Fenton-like Processes in Highly Saline Solutions. [PDF]

Molecules
Orts X, Arévalo J, Arques A, Amat AM, Santos-Juanes L.   +4 more
europepmc   +1 more source

Drug discovery and preclinical testing of drug candidates for developmental and epileptic encephalopathies

Epilepsia, EarlyView.
Abstract Drug development for developmental and epileptic encephalopathies (DEEs) follows different strategies on one hand including disease‐targeting precision medicine approaches considering the genetic variants and pathomechanisms in DEEs and on the other hand including therapeutic approaches with novel targets or second‐generation drug candidates ...
Heidrun Potschka, Daniel Pérez‐Pérez
wiley   +1 more source

Kinetics of Phase Transitions in Amorphous Carbamazepine: From Sub-<i>T_g</i> Structural Relaxation to High-Temperature Decomposition. [PDF]

Int J Mol Sci
Svoboda R, Pospíšilová A.
europepmc   +1 more source

Climate change and hyponatremia‐related hospital admissions in people with focal epilepsy exposed to carbamazepine or its derivatives

Epilepsia, EarlyView.
Abstract Objective To estimate the proportion of individuals with focal epilepsy treated with at least one among carbamazepine (CBZ), oxcarbazepine (OXC), or eslicarbazepine (ESL), who were hospitalized due to hyponatremia‐related symptoms in 2024, and to test the hypothesis that there is an association with climatic variables.
Francesco Fortunato, Francesco D'Amico, Anny Votano, Ilaria Sammarra, Environmental Climate Observatory Group – CNR‐ISAC Lamezia Terme, Claudia R. Calidonna, Ivano Ammoscato, Teresa Lo Feudo, Daniel Gullì, Luana Malacaria, Giorgia De Benedetto, Salvatore Sinopoli, Michele Trimboli, Medine I. Gulcebi, James D. Mills, Simona Balestrini, Sanjay M. Sisodiya, Antonio Gambardella   +17 more
wiley   +1 more source

Fall-Related Adverse Events of Anti-Epileptic Drugs used for Neuropathic Pain in Older Adults: A systematic Review and Meta-Analysis

Vamadevan A, Vijayan V, Marwein F, Yoosuf N.   +3 more
europepmc   +1 more source

Uptake, Partitioning, and Accumulation of High and Low Rates of Carbamazepine in Hydroponically Grown Lettuce (<i>Lactuca sativa</i> var. <i>capitata</i>). [PDF]

Plants (Basel)
Stamm ER, Coldren C, Williams C, Simpson C.   +3 more
europepmc   +1 more source

PAC‐FOS: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures

Epilepsia, EarlyView.
Abstract Objective Central to the development of novel antiseizure medications (ASMs) is testing of antiseizure activity in preclinical models. Although various well‐established models exist, their predictive validity across the spectrum of clinical epilepsies has been less clear.
Lyndsey L. Anderson, Kristopher M. Kahlig, Melissa L. Barker‐Haliski, Lillian G. Matthews, Hamish D. Toop, Brian Hannigan, Jacqueline French, H. Steve White, Marcio Souza, Steven Petrou   +9 more
wiley   +1 more source

Distinct impacts of sodium channel blockers on the strength-duration properties of human motor cortex neurones

Rocchi L, Brown K, Santo AD, Smith H, Peterchev AV, Rothwell JC, Hannah R.   +6 more
europepmc   +1 more source