Results 241 to 250 of about 5,020 (299)

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Tooth-Whitening Agents and Polymer-Based Carriers: Efficacy, Safety, and Clinical Perspectives. [PDF]

Polymers (Basel)
Lin PY, Chen LN, Tseng CF, Chen YS, Lin HY, Vo TTT, Peng TY, Lee IT.   +7 more
europepmc   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Recurrent Discoloration After Internal Bleaching Postregenerative Endodontics. [PDF]

Case Rep Dent
Drouri S, Batty M, Baz SE, Merini HE.
europepmc   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

To Bleach or Not to Bleach?-The Role of Bleaching in the Clinical Workflow for the Treatment of Demarcated Opacities in Anterior Teeth. [PDF]

J Esthet Restor Dent
Greenwall L, Cebula M, Greenwall-Cohen J, Schwendicke F, Effenberger S.   +4 more
europepmc   +1 more source

In Vitro Comparison of Three Chairside Bleaching Protocols: Effects on Enamel Microhardness, Colour, and Qualitative Cytotoxicity Risk. [PDF]

Dent J (Basel)
Buzatu BLR, Balean O, Luca MM, Buzatu R, Galuscan A, Dumitrescu R, Alexa V, Bolchis V, Jumanca DE.   +8 more
europepmc   +1 more source

Enamel and Bleaching or Breaching: Vickers Hardness and Backscattered Electron Imaging. [PDF]

Calcif Tissue Int
Boyde A, Ashrafianbonab S, Mills D.
europepmc   +1 more source

Effect of low-concentration at-home bleaching gels on whitening and tooth sensitivity: a split mouth randomized clinical trial. [PDF]

BMC Oral Health
Chu S, Wang Y, Duan Z, Wu P, Wang Y.
europepmc   +1 more source