Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis [PDF]
Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging.
Abu Sin, Muna +79 more
core +6 more sources
ABSTRACT Background Multidrug‐resistant organism colonization and infections cause significant morbidity and mortality in solid organ transplantation, affecting the perioperative antibiotic management. Yet, international practices for screening and antibiotic prophylaxis in colonized donors and recipients remain poorly defined.
Julia Bini Viotti +8 more
wiley +1 more source
Carbapenemase-producing Enterobacteriaceae: A diagnostic, epidemiological and therapeutic challenge
The global spread of carbapenemase-producing Enterobacteriaceae (CPE) has become a public health problem. Not all CPE are resistant to carbapenems creating a diagnostic and therapeutic challenge.
María Virginia Villegas
doaj +1 more source
Background: Carbapenem-resistant Enterobacteriaceae (CRE) is of utmost clinical importance because they challenge the armamentarium of the treating clinicians, hampering current treatment strategies.
Puneet Bhatt +5 more
doaj +1 more source
A blaVIM-2 Plasmid Disseminating in Extensively Drug-Resistant Clinical Pseudomonas aeruginosa and Serratia marcescens Isolates [PDF]
Infections caused by carbapenem-resistant Enterobacteriaceae isolates are an issue of major global concern (1). Genes coding for metallo-β-lactamases (MβLs) identified in clinical isolates are associated with mobile elements and subject to horizontal ...
Centron, Daniela +9 more
core +2 more sources
The effect of negative, single and multi‐organism positive cultures on outcomes following PCNL
Abstract Objective This study aims to explore risk factors related to positive single and multi‐organism stone cultures and their association with postoperative complications in patients undergoing percutaneous nephrolithotomy (PCNL). Subjects/Patients and Methods A retrospective review was performed on 293 PCNL patients with stone cultures at a single
Katya Hanessian +8 more
wiley +1 more source
OXA-48-producing Enterobacteriaceae in North of Morocco: Data from regional hospital of Tangier
Introduction: This is a three-year retro-prospective study aimed at assessing the prevalence of carbapenem-resistant Enterobacteriaceae and to study three-year retrospective study aimed at determining the prevalence of carbapenem-resistant ...
Younes Mahrach +4 more
doaj +1 more source
Background: There is paucity of data describing the impact of COVID-19 pandemic on antimicrobial resistance. This review evaluated the changes in the rate of multidrug resistant gram negative and gram positive bacteria during the COVID-19 pandemic ...
Usman Abubakar +3 more
doaj +1 more source
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A +173 more
core +4 more sources
Novel nanoparticle‐mediated plasmid delivery in bacteria for difficult applications
Abstract BACKGROUND This study presents the development and application of magnetite/silver‐pDMAEMA‐PEG‐BUFII nanobioconjugates as an advanced plasmid delivery system in bacteria. These nanobioconjugates demonstrated superior efficiency compared to traditional methods in four challenging applications: (i) genomic editing in Gram‐positive bacteria; (ii)
Laura D. Páez‐Angarita +6 more
wiley +1 more source

