Results 61 to 70 of about 17,882 (226)

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis [PDF]

open access: yes, 2018
Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging.
Abu Sin, Muna   +79 more
core   +6 more sources

OXA-48-producing Enterobacteriaceae in North of Morocco: Data from regional hospital of Tangier

open access: yesJournal of Infection in Developing Countries
Introduction: This is a three-year retro-prospective study aimed at assessing the prevalence of carbapenem-resistant Enterobacteriaceae and to study three-year retrospective study aimed at determining the prevalence of carbapenem-resistant ...
Younes Mahrach   +4 more
doaj   +1 more source

Carbapenemase-producing Enterobacteriaceae: A diagnostic, epidemiological and therapeutic challenge

open access: yesInfectio, 2019
The global spread of carbapenemase-producing Enterobacteriaceae (CPE) has become a public health problem. Not all CPE are resistant to carbapenems creating a diagnostic and therapeutic challenge.
María Virginia Villegas
doaj   +1 more source

Detection of blaNDM‐1 and blaIMP‐1 Metallo‐β‐Lactamases in Meropenem‐Resistant Clinical Escherichia coli Isolates Using Modified Carbapenem Inactivation Method (mCIM) and PCR Techniques

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study examines the prevalence of blaNDM‐1 and blaIMP‐1 metallo‐β‐lactamase genes in meropenem‐resistant Escherichia coli isolates using mCIM and PCR. The results indicate a higher prevalence of blaNDM‐1 and suggest the presence of alternative resistance mechanisms in some strains, emphasizing the need for further research on antimicrobial ...
Mehdi Roshdi Maleki
wiley   +1 more source

A blaVIM-2 Plasmid Disseminating in Extensively Drug-Resistant Clinical Pseudomonas aeruginosa and Serratia marcescens Isolates [PDF]

open access: yes, 2014
Infections caused by carbapenem-resistant Enterobacteriaceae isolates are an issue of major global concern (1). Genes coding for metallo-β-lactamases (MβLs) identified in clinical isolates are associated with mobile elements and subject to horizontal ...
Centron, Daniela   +9 more
core   +2 more sources

Emergence of colistin resistance in the largest university hospital complex of São Paulo, Brazil, over five years

open access: yesBrazilian Journal of Infectious Diseases, 2017
Colistin resistance involving Gram-negative bacilli infections is a challenge for health institutions around of the world. Carbapenem-resistance among these isolates makes colistin the last therapeutic option for this treatment. Colistin resistance among
Flávia Rossi   +5 more
doaj   +1 more source

Phenotypic, Targeted Genotypic, and Antimicrobial Susceptibility Profiling of Extended‐Spectrum β‐Lactamase Production and Exclusive blaOXA−48 Gene Detection in Escherichia coli and Klebsiella pneumoniae Isolates From a South Lebanese Hospital

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study investigates the prevalence of multidrug‐resistant Escherichia coli and Klebsiella pneumoniae in South Lebanon's Saida region, focusing on ESBL and carbapenemase production. Results showed a high prevalence of ESBL producers (89.5%) and a lower rate of carbapenemase producers (10.5%), with blaCTX‐M being the most common ESBL gene.
Aya Kahil, Elie Salem Sokhn
wiley   +1 more source

Evaluation of the Blue-Carba test for rapid detection of carbapenemases in gram-negative Bacilli [PDF]

open access: yes, 2015
The Blue-Carba test (BCT) is a biochemical test for rapid (2 h)detection of carbapenemase production in Gram-negative bacillidirectly from bacterial culture .
Albornoz, Ezequiel Pablo   +7 more
core   +1 more source

Hospital sewage in Brazil: a reservoir of multidrug-resistant carbapenemase-producing Enterobacteriaceae [PDF]

open access: yesBrazilian Journal of Biology
The One Health concept recognizes that human health is clearly linked to the health of animals and the environment. Infections caused by bacteria resistant to carbapenem antibiotics have become a major challenge in hospitals due to limited therapeutic ...
D. L. D. R. Gonçalves   +5 more
doaj   +1 more source

Novel nanoparticle‐mediated plasmid delivery in bacteria for difficult applications

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND This study presents the development and application of magnetite/silver‐pDMAEMA‐PEG‐BUFII nanobioconjugates as an advanced plasmid delivery system in bacteria. These nanobioconjugates demonstrated superior efficiency compared to traditional methods in four challenging applications: (i) genomic editing in Gram‐positive bacteria; (ii)
Laura D. Páez‐Angarita   +6 more
wiley   +1 more source

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