Results 81 to 90 of about 75,611 (308)

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A, A, A, A, A, A, A, A, A, A, A, A, A, AA, AC, AH, AJ, AK, AK, AM, AW, B, B, B, B, BJ, C, C, C, C, CA, CA, CE, D, D, D, DG, DP, E, EA, EE, F, F, F, F, FA, FM, FM, G, G, G, G, G, G, G, GA, GP, H, H, H, H, HAS, HE, I, I, I, I, IJ, J, J, JA, JE, JF, JG, JJ, JJ, JL, JR, JR, JR, JV, K, K, K, K, KA, KC, KYY, L, LJ, M, M, M, M, M, M, M, M, M, M, M, M, M, MA, MA, MA, MA, MC, MG, MM, MN, MP, N, N, NT, O, OR, P, P, P, P, PF, PK, R, R, R, R, R, R, R, RB, RG, RM, RR, RR, RS, RV, S, S, S, S, S, S, S, S, S, Sartelli, SJ, SK, SK, SM, SR, SR, SY, T, T, TL, TM, V, V, VG, VN, W, W, W, WL, WR, Y, YF, YH, YR, YS, Z, ZJ   +173 more
core   +4 more sources

CRISPR-Cas9-Mediated Carbapenemase Gene and Plasmid Curing in Carbapenem-Resistant Enterobacteriaceae

Antimicrobial Agents and Chemotherapy, 2020
Combating plasmid-mediated carbapenem resistance is essential to control and prevent the dissemination of carbapenem-resistant Enterobacteriaceae (CRE). Here, we conducted a proof-of-concept study to demonstrate that CRISPR-Cas9-mediated resistance gene ...
M. Hao, Yu-Zhang He, Haifang Zhang, Xiao-ping Liao, Yahong Liu, Jian Sun, Hong Du, B. Kreiswirth, Liang Chen   +8 more
semanticscholar   +1 more source

NDM Production as a Dominant Feature in Carbapenem-Resistant Enterobacteriaceae Isolates from a Tertiary Care Hospital

Antibiotics, 2021
The worldwide spread and increasing prevalence of carbapenem-resistant Enterobacteriaceae (CRE) is of utmost concern and a problem for public health. This resistance is mainly conferred by carbapenemase production.
Fakhur Uddin, S. H. Imam, Saeed Khan, T. Khan, Zulfiqar Ahmed, M. Sohail, Ashraf Y. Elnaggar, Ahmed M. Fallatah, Z. M. El-Bahy   +8 more
semanticscholar   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

A blaVIM-2 Plasmid Disseminating in Extensively Drug-Resistant Clinical Pseudomonas aeruginosa and Serratia marcescens Isolates [PDF]

, 2014
Infections caused by carbapenem-resistant Enterobacteriaceae isolates are an issue of major global concern (1). Genes coding for metallo-β-lactamases (MβLs) identified in clinical isolates are associated with mobile elements and subject to horizontal ...
Centron, Daniela, Deraspe, Maxime, Famiglietti, Angela María Rosa, Kovensky, Jaime, Pistorio, Mariano, Quiroga, Cecilia, Raymond, Frédéric, Rodriguez, Hernan Bernardo, Roy, Paul H., Vilacoba, Elisabet   +9 more
core   +2 more sources

Global trends and hotspots in research of carbapenem-resistant Enterobacteriaceae (CRE): a bibliometric analysis from 2010 to 2020.

Annals of Palliative Medicine, 2021
BACKGROUND Infectious disease caused by carbapenem-resistant Enterobacteriaceae (CRE) has become one of the most serious challenges due to its high morbidity and mortality and research on it has aroused great concern worldwide in the last decade. Thus, a
Han Zhong, Fang Chen, Yujie Li, Xianyuan Zhao, Zai-Li Zhang, Zhi-Chun Gu, Yue-Tian Yu   +6 more
semanticscholar   +1 more source

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

OXA-48-producing Enterobacteriaceae in North of Morocco: Data from regional hospital of Tangier

Journal of Infection in Developing Countries
Introduction: This is a three-year retro-prospective study aimed at assessing the prevalence of carbapenem-resistant Enterobacteriaceae and to study three-year retrospective study aimed at determining the prevalence of carbapenem-resistant ...
Younes Mahrach, Nadira Mourabit, Mohamed Bakkali, Abdelhay Arakrak, Amine Laglaoui   +4 more
doaj   +1 more source

Emergence of colistin resistance in the largest university hospital complex of São Paulo, Brazil, over five years

Brazilian Journal of Infectious Diseases, 2017
Colistin resistance involving Gram-negative bacilli infections is a challenge for health institutions around of the world. Carbapenem-resistance among these isolates makes colistin the last therapeutic option for this treatment. Colistin resistance among
Flávia Rossi, Raquel Girardello, Ana Paula Cury, Thais Sabato Romano Di Gioia, João Nóbrega de Almeida, Jr, Alberto José da Silva Duarte   +5 more
doaj   +1 more source

Impact of COVID-19 pandemic on multidrug resistant gram positive and gram negative pathogens: A systematic review

Journal of Infection and Public Health, 2023
Background: There is paucity of data describing the impact of COVID-19 pandemic on antimicrobial resistance. This review evaluated the changes in the rate of multidrug resistant gram negative and gram positive bacteria during the COVID-19 pandemic ...
Usman Abubakar, Menier Al-Anazi, Zainab alanazi, Jesús Rodríguez-Baño   +3 more
doaj   +1 more source