Results 1 to 10 of about 371 (94)
The modified Hodge test is a useful tool for ruling out Klebsiella pneumoniae carbapenemase
Clinics, 2012 OBJECTIVE: Enterobacteriaceae bacteria harboring Klebsiella pneumoniae carbapenemase are a serious worldwide threat. The molecular identification of these pathogens is not routine in Brazilian hospitals, and a rapid phenotypic screening test is desirable.
Ana Paula Cury +4 more
doaj +7 more sources
Phenotypic Detection of Carbapenemase Production in Carbapenem-Resistant Enterobacteriaceae by Modified Hodge Test and Modified Strip Carba NP Test [PDF]
Journal of Laboratory Physicians, 2021 Abstract Objective Carbapenems are last resort antibiotics for multidrug-resistant Enterobacteriaceae. However, resistance to carbapenem is increasing at an alarming rate worldwide leading to major therapeutic failures and increased mortality rate. Early and effective detection of carbapenemase producing carbapenem-resistant Enterobacteriaceae (CRE) is
Babita Sharma
exaly +3 more sources
Triton Hodge Test: Improved Protocol for Modified Hodge Test for Enhanced Detection of NDM and Other Carbapenemase Producers [PDF]
Journal of Clinical Microbiology, 2016 ABSTRACT Accurate detection of carbapenemase-producing Gram-negative bacilli is of utmost importance for the control of nosocomial spread and the initiation of appropriate antimicrobial therapy. The modified Hodge test (MHT), a carbapenem inactivation assay, has shown poor sensitivity in detecting the worldwide spread of New Delhi metallo-β ...
Fernando Pasterán +2 more
exaly +4 more sources
Characterization of the modified Hodge test-positive isolates of Enterobacteriaceae in Taiwan
Journal of Microbiology, Immunology and Infection, 2013 The modified Hodge test is a phenotypic test to detect KPC-type carbapenemase producers among Enterobacteriaceae, as recommended by the Clinical Laboratory Standards Institute. However, false positive results were reported. In this study, we aimed to large-scale investigate the characterization of the modified Hodge test-positive isolates of ...
Jiunn-Jong Wu +2 more
exaly +3 more sources
Value of the Modified Hodge Test for Detection of Emerging Carbapenemases in Enterobacteriaceae [PDF]
Journal of Clinical Microbiology, 2012 ABSTRACT The modified Hodge test has an excellent sensitivity for detecting enterobacterial isolates producing Ambler class A (KPC) and class D (OXA-48) carbapenemases. Its sensitivity is low for NDM-1 producers (50%) but is increased to 85.7% by adding ZnSO 4 (100 μg/ml) in the culture medium.
Laurent Poirel +2 more
exaly +3 more sources
Clinics, 2013 Dear Editor, We read the article by Cury et al. titled ‘‘The modified Hodge test is a useful tool for ruling out Klebsiella pneumoniae carbapenemase” with interest (1). The authors aimed to evaluate the modified Hodge test (MHT) as a phenotypic screening test for Klebsiella pneumoniae carbapenemase (KPC).
Mustafa Hatipoglu +5 more
doaj +4 more sources
Comparison of Disc Diffusion, Broth Microdilution and Modified Hodge Test Susceptibility Testing Of Escherichia coli Isolates to Beta-Lactam Antibiotics [PDF]
Medical Laboratory Journal, 2016 Background and Objective: One of the main tasks of clinical microbiology laboratories is to determine antibiotic resistance profiles in common pathogens and ensure the selection of effective antibiotics for certain infections.
Hesam Alizade +5 more
doaj +2 more sources
Modified Hodge test: A simple and effective test for detection of carbapenemase production
Iranian Journal of Microbiology, 2011 Background and Objectives: Resistance among bacterial isolates is the leading cause of increased mortality and morbidity worldwide. Carbapenems once thought to be effective are becoming ineffective mostly due to the emergence of carbapenemase. This study
A Amjad +5 more
doaj +2 more sources
Functional categorization of carbapenemase-mediated resistance by a combined genotyping and two-tiered Modified Hodge Test approach [PDF]
Frontiers in Microbiology, 2015 The functional relationship between the detection of carbapenemase activity and phenotypic resistance in Gram-negative bacterial pathogens is often ill-defined. To address this issue, we developed a two-tiered Modified Hodge Test approach for carbapenemase detection and typing, in which the use of Pseudomonas aeruginosa strain PAO1 and Escherichia coli
Marcus H Wong, Sheng Chen
exaly +5 more sources
Journal of Microbiological Methods, 2010 The detection of carbapenemases in Gram-negative bacilli is important for optimal patient treatment and to control spread of the resistance. The modified Hodge test can detect carbapenemase-producing Gram-negative bacilli. In this study, we compared the performance of MacConkey agar and Mueller-Hinton agar for metallo-β-lactamase (MBL) and OXA ...
Yunsop Chong +2 more
exaly +4 more sources