Results 21 to 30 of about 8,380,744 (215)
Frequency of Carbapenemase Producing Klebsiella pneumoniae in Makkah, Saudi Arabia [PDF]
Journal of Microbiology and Infectious Diseases, 2017 Objective: Carbapenemase producing Klebsiella pneumoniae is emerging as an important pathogen worldwide which has alarming clinical threat with serious effects on patients’ outcome.
Mubashir Ahmad Khan, Aftab Faiz
doaj +1 more source
Adaptation of a Fluorogenic RNA to N1‐Methylpseudouridine Nucleoside Chemistry
Angewandte Chemie, EarlyView.Several green‐emitting fluorogenic RNA aptamers were evaluated following the replacement of every uridine by N1‐methylpseudouridine (mΨ). Because this modification impaired the function of most aptamers, a directed evolution strategy combining droplet microfluidics, bioinformatics, and rational design was used to identify an aptamer preserving its ...
Patrick P.A. Bertrand +4 more
wiley +2 more sources
Iranian Journal of Microbiology, 2022 Background and Objectives: Acinetobacter baumannii has emerged as a major organism accounting for hospital acquired infections particularly in intensive care units.
Morubagal Raghavendra Rao +6 more
doaj +1 more source
Comparative Evaluation of Four Phenotypic Tests for Detection of Metallo-β-Lactamase and Carbapenemase Production in Acinetobacter baumannii [PDF]
Journal of Clinical and Diagnostic Research, 2014 Introduction: Acinetobacter baumannii is an emerging multidrug resistant opportunistic pathogen that causes a variety of nosocomial infections. In recent years, carbapenem resistance in A.baumannii has increased due to Ambler class B Metallo β ...
Aparna Shivaprasad +2 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2018 Objective: To determine the prevalence of Amp C beta lactamases in urinary isolates of Escherichia coli (E. coli), and to evaluate and compare different phenotypic methods for its detection in a cost effective way.
Qanita Fahim +3 more
doaj +4 more sources
Detection of Carbapenemase Producing Gram-negative Bacteria at a Tertiary Care Hospital: A Cross-sectional Study [PDF]
National Journal of Laboratory MedicineIntroduction: Gram-negative bacteria have developed a broad spectrum of resistance due to antibiotic degradation enzymes, including Extended-spectrum Beta-lactamases (ESBL), AmpC β-lactamases, and carbapenemases.
Rajeswari Pilli +3 more
doaj +1 more source
Utility of phenotypic methods in detection of metallo-beta-lactamases in gram-negative bacteria
Journal of Marine Medical Society, 2020 Background: Metallo-beta-lactamases (MBLs)-producing Gram-negative bacilli (GNB) are one of the significant multidrug-resistant pathogens causing healthcare-associated infection (HAI) worldwide.
Dinesh Kumar Kalra +5 more
doaj +1 more source
blaKPC gene Detection in Clinical Isolates of Carbapenem Resistant Enterobacteriaceae in a Tertiary Care Hospital [PDF]
Journal of Clinical and Diagnostic Research, 2013 Introduction: Carbapenem resistance among Enterobacteriaceae, especially in Klebsiella pneumoniae and Escherichia coli, is an emerging problem worldwide.
Priyadarshini Shanmugam +2 more
doaj +1 more source
Advanced Science, EarlyView.The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo +20 more
wiley +1 more source
Advanced Science, EarlyView.Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li +21 more
wiley +1 more source