SOME STRANGE FINDINGS: NON-INTERPRETABLE PATTERNS IN MODIFIED HODGE TEST
Many clinically relevant species of Gram-negative bacilli are often resistant to β-lactam antibiotics even to carbapenems. According to CLSI guideline 2013, Carbapenemase producers are screened by zone size
Jayashree Konar, Indrani Bhattacharyya
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Objective: To determine the prevalence of Amp C beta lactamases in urinary isolates of Escherichia coli (E. coli), and to evaluate and compare different phenotypic methods for its detection in a cost effective way. Study Design: Descriptive study. Place
Qanita Fahim +3 more
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Detection of Carbapenemase Producing Gram-negative Bacteria at a Tertiary Care Hospital: A Cross-sectional Study [PDF]
Introduction: Gram-negative bacteria have developed a broad spectrum of resistance due to antibiotic degradation enzymes, including Extended-spectrum Beta-lactamases (ESBL), AmpC β-lactamases, and carbapenemases.
Rajeswari Pilli +3 more
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blaKPC gene Detection in Clinical Isolates of Carbapenem Resistant Enterobacteriaceae in a Tertiary Care Hospital [PDF]
Introduction: Carbapenem resistance among Enterobacteriaceae, especially in Klebsiella pneumoniae and Escherichia coli, is an emerging problem worldwide.
Priyadarshini Shanmugam +2 more
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Phenotypic detection of Carbapenamase among Klebsiella pneumoniae isolated from clinical samples using modified Hodged test [PDF]
Carbapenemases are microbial enzymes that confer resistance to virtually all available beta-lactam antibiotics and the most frequent carbapenemases are the Klebsiella pneumoniae Carbapenamase (KPC). Detection of carbapenemases is a significant infection control strategy as the enzymes are often associated with extensive antimicrobial resistance ...
HauwaYakubu +5 more
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Aim: the goal of this study is to understand the phenotype characteristic of beta-lactamase enzymes producing Enterobacteriaceae, such as ESBL, AmpC, and carbapenemase.
Yulia R Saharman, Delly C Lestari
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Utility of phenotypic methods in detection of metallo-beta-lactamases in gram-negative bacteria
Background: Metallo-beta-lactamases (MBLs)-producing Gram-negative bacilli (GNB) are one of the significant multidrug-resistant pathogens causing healthcare-associated infection (HAI) worldwide.
Dinesh Kumar Kalra +5 more
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Objective: To assess the effectiveness of Modified Hodge test (MHT) and Modified carbapenemase inactivation method (mCIM) for detection of carbapenemase enzyme produced by Pseudomonas aeruginosa strains that code for resistance towards carbapenem. Study
Shaista Bakhat +3 more
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Significance of Modified Hodge Test in Carbapenemase Detection: A Brief Insight
Neonatal sepsis is one of the leading causes of neonatal deaths. A. baumannii-calcoaceticus is the most notorious bacterial agent. Carbapenems are the most important antibiotics and modified Hodge Test is considered as important phenotypic method for observing Carbapenemase production.
Romah Ishfaq +5 more
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Comparison of Various Phenotypic Methods in Detection of Carbapenemases and Metallo-Beta-Lactamases (MBL) in Carbapenem Resistant Clinlical Isolates of Acinetobacter Species at A Tertiary Care Centre [PDF]
Background & Aims: carbapenem-resistant strains of Acinetobacter baumannii (A. baumannii) have been reported worldwide over the last decade. Detection of the carbapenemases is crucial to determine the severity of the problem. The aim of our study was to
Mariya Rouf +3 more
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