Results 11 to 20 of about 5,100 (223)

Modified Hodge Test versus Indirect Carbapenemase Test: Prospective Evaluation of a Phenotypic Assay for Detection of Klebsiella pneumoniae Carbapenemase (KPC) in Enterobacteriaceae [PDF]

Journal of Clinical Microbiology, 2013
ABSTRACT The currently recommended phenotypic test for the detection of carbapenemase-producing members of the family Enterobacteriaceae is the modified Hodge test (MHT). However, the MHT lacks specificity.
Costi Sifri, Amy Mathers, Kevin C Hazen   +2 more
exaly   +4 more sources

Performance of Quantification of Modified Hodge Test: An Evaluation withKlebsiella pneumoniaeCarbapenemase-Producing Enterobacteriaceae Isolates [PDF]

BioMed Research International, 2014
Modified Hodge Test (MHT) has been suggested as screening tests for carbapenemases, but concerns regarding its difficult interpretation and common false-positive results obtained in the presence of otherβ-lactamases have been noted. This study aimed to quantify the enhanced growth formed by the indicator strain and thus evaluate the performance of a ...
Ribeiro, Vanessa Bley, Linhares, Adriano Rostirolla, Zavascki, Alexandre P., Barth, Afonso Luis   +3 more
openaire   +3 more sources

Evaluation of Modified Hodge Test as a Non-molecular Assay for Accurate Detection of KPC-producing Klebsiella pneumoniae [PDF]

Polish Journal of Microbiology, 2018
Abstract Klebsiella pneumoniae carbapenemase (KPC) have become a major therapeutic challenge because of its increasingly fast dissemination throughout the world. Accurate detection of KPC is essential for optimal treatment.
ATOSSA GHASEMNEJAD, MONIR DOUDI, NOUR AMIRMOZAFARI   +2 more
openaire   +4 more sources

Screening for New Delhi metallo-?-lactamase-1 in Enterobacteriaceae: Is there a role for the modified Hodge test? [PDF]

Pakistan Journal of Medical Sciences, 2015
Objective: The New Delhi metallo-?-lactamase-1 (NDM-1) enzyme is a plasmid-encoded enzyme that inactivates carbapenem antibiotics. This study aims to ascertain if the modified Hodge test (MHT) has a role in screening for NDM-1 in Enterobacteriaceae with reduced carbapenem susceptibility.Methods: Over a period of one year, all Enterobacteriaceae ...
Abidin, Nor Zanariah Zainol, Sulong, Anita, Alfizah, Hanafiah, Ding, Chuan Hun, Muttaqillah, Najihan Abdul Samat, Rahman, Md Mostafizur   +5 more
openaire   +3 more sources

Further Modification of the Modified Hodge Test for Detecting Metallo-β-Lactamase-Producing Carbapenem-Resistant Enterobacteriaceae [PDF]

Annals of Laboratory Medicine, 2015
The modified Hodge test (MHT) was designed to detect carbapenemase-producing Enterobacteriaceae (CPE). This study evaluated variables to improve the performance of MHT.Carbapenem-resistant Enterobacteriaceae isolated from November 2010 to March 2013 at the Asan Medical Center, were evaluated, including 33 metallo-β-lactamase (MBL) producers and 103 non-
Kim, Hyun-Ki, Park, Jeong Su, Sung, Heungsup, Kim, Mi-Na   +3 more
openaire   +3 more sources

Comparison of a Novel, Rapid Chromogenic Biochemical Assay, the Carba NP Test, with the Modified Hodge Test for Detection of Carbapenemase-Producing Gram-Negative Bacilli [PDF]

Journal of Clinical Microbiology, 2013
ABSTRACT We compared carbapenemase detection among 271 Gram-negative bacilli (of which 131 were carbapenemase producers) using a novel chromogenic rapid test—the Carba NP test (CNP)—and the modified Hodge test (MHT). Sensitivities were comparable (CNP, 100%, versus MHT, 98%; P = 0.08), but CNP was more ...
Shawn, Vasoo, Scott A, Cunningham, Peggy C, Kohner, Patricia J, Simner, Jayawant N, Mandrekar, Karen, Lolans, Mary K, Hayden, Robin, Patel   +7 more
openaire   +3 more sources

The Modified Hodge Test: Is it an appropriate method for detection of KPC enzyme or not? [PDF]

Iranian journal of microbiology, 2015
LETTER TO THE ...
Davood Kalantar-Neyestanaki, Mehdi Fatahi Bafghi   +1 more
openaire   +3 more sources

Modified Hodge test: A useful and the low-cost phenotypic method for detection of carbapenemase producers in Enterobacteriaceae members

Journal of Natural Science, Biology and Medicine, 2013
The global spread of antimicrobial resistance has acquired greater significance in the public health perspective. Drug resistance has posed a threat for the management of various hospital-acquired infections (HAI). For bacteria producing extended spectrum ß lactamase, carbapenems are the drug of choice.
Ramana, K. V., Rao, Ratna, Sharada, CH. V, Kareem, MA, Reddy, L. Rajashekar, Ratna Mani, MS   +5 more
openaire   +4 more sources

Combined Use of the Modified Hodge Test and Carbapenemase Inhibition Test for Detection of Carbapenemase-ProducingEnterobacteriaceaeand Metallo-β-Lactamase-ProducingPseudomonasspp. [PDF]

Annals of Laboratory Medicine, 2015
We evaluated the combined use of the modified Hodge test (MHT) and carbapenemase inhibition test (CIT) using phenylboronic acid (PBA) and EDTA to detect carbapenemase-producing Enterobacteriaceae (CPE) and metallo-β-lactamase (MBL)-producing Pseudomonas spp.A total of 49 isolates of CPE (15 Klebsiella pneumoniae carbapenemase [KPC], 5 Guiana extended ...
Song, Wonkeun, Hong, Seong Geun, Yong, Dongeun, Jeong, Seok Hoon, Kim, Hyun Soo, Kim, Han-Sung, Kim, Jae-Seok, Bae, Il Kwon   +7 more
openaire   +4 more sources

A possible alternative to the error prone modified Hodge test to correctly identify the carbapenemase producing Gram-negative bacteria

Indian Journal of Medical Microbiology, 2014
The modified Hodge test (MHT) is widely used as a screening test for the detection of carbapenemases in Gram-negative bacteria. This test has several pitfalls in terms of validity and interpretation. Also the test has a very low sensitivity in detecting the New Delhi metallo-β-lactamase (NDM).
S Anandan
exaly   +3 more sources