Results 91 to 100 of about 19,811 (179)

Novel drug candidates against antibiotic-resistant microorganisms: A review [PDF]

Iranian Journal of Basic Medical Sciences
Antibiotic resistance is fast spreading globally, leading to treatment failures and adverse clinical outcomes. This review focuses on the resistance mechanisms of the top five threatening pathogens identified by the World Health Organization’s global ...
Jing-Sheng Lim, Yoke-Yen Chai, Wei-Xin Ser, Aniqah Van Haeren, Yan-Hong Lim, Tarshiiny Raja, Jhi-Biau Foo, Sharina Hamzah, Renukha Sellappans, Hui Yin Yow   +9 more
doaj   +1 more source

Evaluation of Resistance Mechanisms in Carbapenem-Resistant Enterobacteriaceae.

Infection and drug resistance, 2020
Carbapenem-resistant Enterobacteriaceae (CRE) is a major concern leading to morbidity and mortality in the world. CRE often is becoming a cause of therapeutic failure in both hospital and community-acquired infections.This study aimed to investigate the resistance mechanisms of CRE by phenotypic and molecular methods.Sixty CRE (50 Klebsiella pneumoniae,
Alizadeh,Naser, Ahangarzadeh Rezaee,Mohammad, Samadi Kafil,Hossein, Hasani,Alka, Soroush Barhaghi,Mohammad Hossein, Milani,Morteza, Yeganeh Sefidan,Fatemeh, Memar,Mohammad Yousef, Lalehzadeh,Aidin, Ghotaslou,Reza   +9 more
openaire   +4 more sources

Appropriate composites of cefoperazone–sulbactam against multidrug-resistant organisms

Infection and Drug Resistance, 2018
Chih-Cheng Lai,1 Chi-Chung Chen,2,3 Ying-Chen Lu,3 Tsuey-Pin Lin,4 Yin-Ching Chuang,2,5 Hung-Jen Tang4,6 1Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, 2Department of Medical Research, Chi Mei Medical Center, Tainan ...
Lai CC, Chen CC, Lu YC, Lin TP, Chuang YC, Tang HJ   +5 more
doaj  

Prevalence of multidrug-resistance and blaVIM and blaIMP genes among gram-negative clinical isolates in tertiary care hospital, Kathmandu, Nepal

Iranian Journal of Microbiology, 2021
Background and Objectives: Carbapenems have been the choice of antibiotics for the treatment of infections caused by multidrug-resistant bacteria. The main objective of this study was to determine the prevalence of carbapenemase (blaVIM and blaIMP ...
Mehraj Ansari, Subhas Chandra Aryal, Ganesh Rai, Kul Raj Rai, Susil Pyakurel, Bina Bhandari, Anil Kumar Sah, Shiba Kumar Rai   +7 more
doaj  

Colonization of the gut by Klebsiella pneumoniae and its multidrug-resistant strains is well marked in preterm neonates

Frontiers in Cellular and Infection Microbiology
BackgroundThe colonization of preterm neonates by multidrug-resistant Enterobacteriaceae, especially in neonatal intensive care units (NICUs), remains poorly understood despite its potential role in healthcare-associated transmission.
Eman Mohammed El-Shanqetti, Hibah M. Albasri, Moayad S. Waznah, Fatthy Mohamed Morsy, Fatthy Mohamed Morsy   +4 more
doaj   +1 more source

Antimicrobial-Resistant Bacteria in Infected Wounds, Ghana, 2014

Emerging Infectious Diseases, 2018
Wound infections are an emerging medical problem worldwide, frequently neglected in under-resourced countries. Bacterial culture and antimicrobial drug resistance testing of infected wounds in patients in a rural hospital in Ghana identified no ...
Hauke Janssen, Iryna Janssen, Paul Cooper, Clemens Kainyah, Theresia Pellio, Michael Quintel, Mathieu Monnheimer, Uwe Groß, Marco H. Schulze   +8 more
doaj   +1 more source

Development and Evaluation of Multiplex PCR for the Detection of Carbapenemase-Producing Enterobacteriaceae

Annals of Clinical Microbiology, 2019
Background: The isolation of carbapenemase-producing Enterobacteriaceae (CPE) has become increasingly common. Continuous surveillance for these organisms is essential because their infections are closely related to outbreaks of illness and are ...
Bareum Gwon, Il Kwon Bae, Na Young Kim, Sae Am Son, Sunjoo Kim, Joseph Jeong, Jeong Hwan Shin   +6 more
doaj   +1 more source

Susceptibility of Tigecycline against Carbapenem Resistant Enterobacteriaceae

Pakistan Journal of Medicine and Dentistry
Background: Enterobacteriaceae, a large family of Gram-negative bacteria, are one of the commonest etiological agents causing serious bacterial infections to humans. Carbapenems are the group of antibiotics with a broad spectrum of antimicrobial action.
Madeeha Fatima, Faisal lqbal Afridi, Hareem Gohar   +2 more
doaj   +1 more source

Phenotypic method for differentiation of carbapenemases in Enterobacteriaceae: Study from north India

Indian Journal of Pathology and Microbiology, 2012
Aims: Carbapenems are usually the choice of antimicrobials in infections caused by Enterobacteriaceae bacteria-producing ESBL (extended spectrum β-lactamases) and Amp C.
Priya Datta, Varsha Gupta, Shivani Garg, Jagdish Chander   +3 more
doaj   +1 more source

Deaths Attributable to Carbapenem-ResistantEnterobacteriaceaeInfections

Emerging Infectious Diseases, 2014
We evaluated the number of deaths attributable to carbapenem-resistant Enterobacteriaceae by using studies from around the world published before April 9, 2012. Attributable death was defined as the difference in all-cause deaths between patients with carbapenem-resistant infections and those with carbapenem-susceptible infections.
Matthew E. Falagas, Giannoula S. Tansarli, Drosos E. Karageorgopoulos, Konstantinos Z. Vardakas   +3 more
openaire   +3 more sources