Results 71 to 80 of about 114,909 (286)

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi   +4 more
wiley   +1 more source

The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]

open access: yes, 2018
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M.   +10 more
core   +1 more source

Carbapenems and febrile neutropenia [PDF]

open access: yesClinical Microbiology and Infection, 2017
International ...
Alfandari, S.   +2 more
openaire   +4 more sources

Glyco‐Nanogels for Modulating Pseudomonas aeruginosa Biofilm

open access: yesMacromolecular Rapid Communications, EarlyView.
Nanogels presenting α‐galactose and β‐fucose can significantly alter Pseudomonas aeruginosa biofilm dynamics through their interaction with lectins. Application timing is crucial: pre‐treatment reduces biofilm, while treatment after biofilm initiation increases biomass.
Sophia Rosencrantz   +4 more
wiley   +1 more source

Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]

open access: yes, 2018
Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung   +8 more
core   +2 more sources

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

open access: yesChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges   +15 more
wiley   +1 more source

Investigation of antimicrobial susceptibility patterns and frequency of bla OXA genes in carbapenem resistant Acinetobacter baumannii strains

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2018
Bachground and Aim: Acinetobacter baumannii is one of the important caues of nosocomial infection. Resistance to antibiotics specially carbapenem antibiotics is on the increase which can be an alarming sign for healthcare managers and personnel.
Mohsen Moghadasi   +5 more
doaj  

Antimicrobial Resistance: We Must Pursue a Collaborative, Global Approach and Use a "One Health" Approach. [PDF]

open access: yes, 2019
Treating infection is a key part of the work of most clinicians [...]
Lipman, J, Lonsdale, DO
core   +1 more source

‘Knowledge, attitudes and practices’ survey of Austrian veterinarians' antibiotic use in clinical practice

open access: yesVeterinary Record, EarlyView.
Abstract Background Antimicrobial resistance (AMR) is a critical global health issue, with antimicrobial use (AMU) in veterinary medicine playing a relevant role in its emergence. This study aimed to evaluate the knowledge, attitudes and practices of Austrian veterinarians regarding AMU and AMR.
Clair L. Firth   +4 more
wiley   +1 more source

Population-Based Pharmacokinetics and Dose Optimization of Imipenem in Vietnamese Critically-Ill Patients

open access: yesInfection and Drug Resistance, 2022
Thanh D Dinh,1,2 Hung N Nguyen,1 Ba Hai Le,1 Thuy TT Nguyen,1 Huong TL Nguyen1 1Department of Clinical Pharmacy, Hanoi University of Pharmacy, Hanoi, Vietnam; 2Phu Tho General Hospital, Việt Trì, Phu Tho Province, VietnamCorrespondence: Huong TL Nguyen ...
Dinh TD   +4 more
doaj  

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