Results 201 to 210 of about 28,203 (214)

The emerging NDM carbapenemases

Trends in Microbiology, 2011
Carbapenems were the last β-lactams retaining near-universal anti-Gram-negative activity, but carbapenemases are spreading, conferring resistance. New Delhi metallo-β-lactamase (NDM) enzymes are the latest carbapenemases to be recognized and since 2008 have been reported worldwide, mostly in bacteria from patients epidemiologically linked to the Indian
Nordmann, Patrice, Poirel, Laurent, Walsh, Timothy R, Livermore, David M   +3 more
openaire   +4 more sources

Carbapenemases: a problem in waiting?

Current Opinion in Microbiology, 2000
Carbapenems are stable to most prevalent beta-lactamases, and chromosomal carbapenemases are restricted to Stenotrophomonas maltophilia, to a few Bacteroides fragilis, and to rare pathogens. Nevertheless, an acquired metallo-beta-lactamase called IMP-1 is beginning to emerge in Pseudomonas aeruginosa and Enterobacteriaceae isolates in Japan, and has ...
Neil Woodford, David M. Livermore
openaire   +3 more sources

Carbapenemases: a worldwide threat

Expert Review of Anti-infective Therapy, 2013
β-lactam antibiotics remain one of our workhorse classes for serious infection due to their usually broad activity and attractive safety profile.
openaire   +3 more sources

Detection systems for carbapenemase gene identification should include the SME serine carbapenemase

International Journal of Antimicrobial Agents, 2013
Carbapenemase detection has become a major problem in hospitals that encounter outbreaks of infections caused by carbapenem-resistant Gram-negative bacteria. Rapid detection systems have been reported using multiplex PCR analyses and DNA microarray assays.
John L. Lock, James H. Jorgensen, Megan Pannell, Karen Bush, James S. Lewis, Anne Marie Queenan, Ryan M. Lee, Deidre Jarrett   +7 more
openaire   +3 more sources

Current methods for the identification of carbapenemases

Journal of Chemotherapy, 2016
Detection of carbapenemases in clinical microbiology labs is a challenging issue. Comparison of the results of susceptibility testing with the breakpoint values of carbapenems is the first step in the screening of carbapenemase producers. To date, screening of carbapenemase-producing (CP) bacteria has been mostly performed by a selective medium ...
Mohammad Asgharzadeh, Hossein Samadi Kafil, Abed Zahedi Bialvaei, Mohammad Yousef Memar, Mehdi Yousefi   +4 more
openaire   +2 more sources