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Carbohydrates [PDF]

Advances in Nutrition, 2014
Although carbohydrates represent one of the most important families of biomolecules, they remain under-studied in comparison to the other biomolecular families (peptides, nucleobases). Beyond their best-known function of energy source in living systems, they act as mediator of molecular recognition processes, carrying molecular information in the so ...
Joanne, Slavin, Justin, Carlson
openaire   +4 more sources

Protocols for isolating and characterizing polysaccharides from plant cell walls: a case study using rhamnogalacturonan-II

Biotechnology for Biofuels, 2021
Background In plants, a large diversity of polysaccharides comprise the cell wall. Each major type of plant cell wall polysaccharide, including cellulose, hemicellulose, and pectin, has distinct structures and functions that contribute to wall mechanics ...
William J. Barnes, Sabina Koj, Ian M. Black, Stephanie A. Archer-Hartmann, Parastoo Azadi, Breeanna R. Urbanowicz, Maria J. Peña, Malcolm A. O’Neill   +7 more
doaj   +1 more source

Regulation of Primary Cilium Length by O-GlcNAc during Neuronal Development in a Human Neuron Model

Cells, 2023
The primary cilium plays critical roles in the homeostasis and development of neurons. Recent studies demonstrate that cilium length is regulated by the metabolic state of cells, as dictated by processes such as glucose flux and O-GlcNAcylation (OGN ...
Jie L. Tian, Chia-Wei Huang, Farzad Eslami, Michael Philip Mannino, Rebecca Lee Mai, Gerald W. Hart   +5 more
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De novo biosynthesis of rubusoside and rebaudiosides in engineered yeasts

Nature Communications, 2022
Rubusoside and rebaudiosides are considered the next generation of sugar substitutes. In this article, the authors report the engineering of Saccharomyces cerevisiae, remodelling the complex metabolic networks by a modular engineering approach, obtaining
Yameng Xu, Xinglong Wang, Chenyang Zhang, Xuan Zhou, Xianhao Xu, Luyao Han, Xueqin Lv, Yanfeng Liu, Song Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu   +13 more
doaj   +1 more source

Site specific N- and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern

Scientific Reports, 2023
The glycosylation on the spike (S) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, modulates the viral infection by altering conformational dynamics, receptor interaction and host immune ...
Asif Shajahan, Lauren E. Pepi, Bhoj Kumar, Nathan B. Murray, Parastoo Azadi   +4 more
doaj   +1 more source

Loss of Arabidopsis GAUT12/IRX8 causes anther indehiscence and leads to reduced G lignin associated with altered matrix polysaccharide deposition

Frontiers in Plant Science, 2014
GAUT12 (GAlactUronosylTransferase12)/IRX8 (IRregular Xylem8) is a putative glycosyltransferase involved in Arabidopsis secondary cell wall biosynthesis.
Zhangying eHao, Zhangying eHao, Zhangying eHao, Utku eAvci, Utku eAvci, Li eTan, Li eTan, Xiang eZhu, Xiang eZhu, John eGlushka, Sivakumar ePattathil, Sivakumar ePattathil, Stefan eEberhard, Tipton eScholes, Grace E. Rothstein, Grace E. Rothstein, Wolfgang eLukowitz, Ron eOrlando, Ron eOrlando, Michael G. Hahn, Michael G. Hahn, Michael G. Hahn, Debra eMohnen, Debra eMohnen, Debra eMohnen   +24 more
doaj   +1 more source

Compartmentalization and transporter engineering strategies for terpenoid synthesis

Microbial Cell Factories, 2022
Microbial cell factories for terpenoid synthesis form a less expensive and more environment-friendly approach than chemical synthesis and extraction, and are thus being regarded as mainstream research recently.
Ke Jin, Hongzhi Xia, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu   +6 more
doaj   +1 more source

Designer biomass for next-generation biorefineries: leveraging recent insights into xylan structure and biosynthesis

Biotechnology for Biofuels, 2017
Xylans are the most abundant noncellulosic polysaccharides in lignified secondary cell walls of woody dicots and in both primary and secondary cell walls of grasses.
Peter J. Smith, Hsin-Tzu Wang, William S. York, Maria J. Peña, Breeanna R. Urbanowicz   +4 more
doaj   +1 more source

Xylan epitope profiling: an enhanced approach to study organ development-dependent changes in xylan structure, biosynthesis, and deposition in plant cell walls

Biotechnology for Biofuels, 2017
Background Xylan is a major hemicellulosic component in the cell walls of higher plants especially in the secondary walls of vascular cells which are playing important roles in physiological processes and overall mechanical strength.
Angelo G. Peralta, Sivasankari Venkatachalam, Sydney C. Stone, Sivakumar Pattathil   +3 more
doaj   +1 more source

NMR analysis suggests the terminal domains of Robo1 remain extended but are rigidified in the presence of heparan sulfate

Scientific Reports, 2022
Human roundabout 1 (hRobo1) is an extracellular receptor glycoprotein that plays important roles in angiogenesis, organ development, and tumor progression.
Robert V. Williams, Chin Huang, Kelley W. Moremen, I. Jonathan Amster, James H. Prestegard   +4 more
doaj   +1 more source