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Although carbohydrates represent one of the most important families of biomolecules, they remain under-studied in comparison to the other biomolecular families (peptides, nucleobases). Beyond their best-known function of energy source in living systems, they act as mediator of molecular recognition processes, carrying molecular information in the so ...
Robert J. Ouellette, J. David Rawn
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Background In plants, a large diversity of polysaccharides comprise the cell wall. Each major type of plant cell wall polysaccharide, including cellulose, hemicellulose, and pectin, has distinct structures and functions that contribute to wall mechanics ...
William J. Barnes +7 more
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Regulation of Primary Cilium Length by O-GlcNAc during Neuronal Development in a Human Neuron Model
The primary cilium plays critical roles in the homeostasis and development of neurons. Recent studies demonstrate that cilium length is regulated by the metabolic state of cells, as dictated by processes such as glucose flux and O-GlcNAcylation (OGN ...
Jie L. Tian +5 more
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De novo biosynthesis of rubusoside and rebaudiosides in engineered yeasts
Rubusoside and rebaudiosides are considered the next generation of sugar substitutes. In this article, the authors report the engineering of Saccharomyces cerevisiae, remodelling the complex metabolic networks by a modular engineering approach, obtaining
Yameng Xu +13 more
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Site specific N- and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern
The glycosylation on the spike (S) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, modulates the viral infection by altering conformational dynamics, receptor interaction and host immune ...
Asif Shajahan +4 more
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Carbohydrates in Cyberspace [PDF]
1 Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia, 2 Centre for Biomedical Research, Burnet Institute, Melbourne, VIC, Australia, 3 Department of Immunology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia, 4 Department of Surgery Austin Health, University of ...
Yuriev, E., Ramsland, Paul
openaire +6 more sources
A nutrigenetic approach to investigate the relationship between metabolic traits and vitamin D status in an Asian Indian population [PDF]
Studies in Asian Indians have examined the association of metabolic traits with vitamin D status. However, findings have been quite inconsistent. Hence, we aimed to explore the relationship between metabolic traits and 25-hydroxyvitamin D [25(OH)D ...
Alathari, Buthaina E. +11 more
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GAUT12 (GAlactUronosylTransferase12)/IRX8 (IRregular Xylem8) is a putative glycosyltransferase involved in Arabidopsis secondary cell wall biosynthesis.
Zhangying eHao +24 more
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Maximizing efficiency of rumen microbial protein production. [PDF]
Rumen microbes produce cellular protein inefficiently partly because they do not direct all ATP toward growth. They direct some ATP toward maintenance functions, as long-recognized, but they also direct ATP toward reserve carbohydrate synthesis and ...
Andries +158 more
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Compartmentalization and transporter engineering strategies for terpenoid synthesis
Microbial cell factories for terpenoid synthesis form a less expensive and more environment-friendly approach than chemical synthesis and extraction, and are thus being regarded as mainstream research recently.
Ke Jin +6 more
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