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Carbohydrates [PDF]

open access: yesAdvances in Nutrition, 2014
Although carbohydrates represent one of the most important families of biomolecules, they remain under-studied in comparison to the other biomolecular families (peptides, nucleobases). Beyond their best-known function of energy source in living systems, they act as mediator of molecular recognition processes, carrying molecular information in the so ...
Robert J. Ouellette, J. David Rawn
  +6 more sources

The carbohydrate-active enzyme database: functions and literature

open access: yesNucleic Acids Res., 2021
Thirty years have elapsed since the emergence of the classification of carbohydrate-active enzymes in sequence-based families that became the CAZy database over 20 years ago, freely available for browsing and download at www.cazy.org. In the era of large
E. Drula   +5 more
semanticscholar   +1 more source

Protocols for isolating and characterizing polysaccharides from plant cell walls: a case study using rhamnogalacturonan-II

open access: yesBiotechnology for Biofuels, 2021
Background In plants, a large diversity of polysaccharides comprise the cell wall. Each major type of plant cell wall polysaccharide, including cellulose, hemicellulose, and pectin, has distinct structures and functions that contribute to wall mechanics ...
William J. Barnes   +7 more
doaj   +1 more source

Regulation of Primary Cilium Length by O-GlcNAc during Neuronal Development in a Human Neuron Model

open access: yesCells, 2023
The primary cilium plays critical roles in the homeostasis and development of neurons. Recent studies demonstrate that cilium length is regulated by the metabolic state of cells, as dictated by processes such as glucose flux and O-GlcNAcylation (OGN ...
Jie L. Tian   +5 more
doaj   +1 more source

De novo biosynthesis of rubusoside and rebaudiosides in engineered yeasts

open access: yesNature Communications, 2022
Rubusoside and rebaudiosides are considered the next generation of sugar substitutes. In this article, the authors report the engineering of Saccharomyces cerevisiae, remodelling the complex metabolic networks by a modular engineering approach, obtaining
Yameng Xu   +13 more
doaj   +1 more source

Site specific N- and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern

open access: yesScientific Reports, 2023
The glycosylation on the spike (S) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, modulates the viral infection by altering conformational dynamics, receptor interaction and host immune ...
Asif Shajahan   +4 more
doaj   +1 more source

Weak carbohydrate-carbohydrate interactions in membrane adhesion are fuzzy and generic [PDF]

open access: yesNanoscale, 2020, DOI: 10.1039/D0NR03696J, 2020
Carbohydrates such as the trisaccharide motif LeX are key constituents of cell surfaces. Despite intense research, the interactions between carbohydrates of apposing cells or membranes are not well understood. In this article, we investigate carbohydrate-carbohydrate interactions in membrane adhesion as well as in solution with extensive atomistic ...
arxiv   +1 more source

Carbohydrates in Cyberspace [PDF]

open access: yesFrontiers in Immunology, 2015
1 Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia, 2 Centre for Biomedical Research, Burnet Institute, Melbourne, VIC, Australia, 3 Department of Immunology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia, 4 Department of Surgery Austin Health, University of ...
Yuriev, E., Ramsland, Paul
openaire   +6 more sources

Compartmentalization and transporter engineering strategies for terpenoid synthesis

open access: yesMicrobial Cell Factories, 2022
Microbial cell factories for terpenoid synthesis form a less expensive and more environment-friendly approach than chemical synthesis and extraction, and are thus being regarded as mainstream research recently.
Ke Jin   +6 more
doaj   +1 more source

Loss of Arabidopsis GAUT12/IRX8 causes anther indehiscence and leads to reduced G lignin associated with altered matrix polysaccharide deposition

open access: yesFrontiers in Plant Science, 2014
GAUT12 (GAlactUronosylTransferase12)/IRX8 (IRregular Xylem8) is a putative glycosyltransferase involved in Arabidopsis secondary cell wall biosynthesis.
Zhangying eHao   +24 more
doaj   +1 more source

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